Zobrazeno 1 - 10
of 39
pro vyhledávání: '"NATALIA PETERSEN"'
Autor:
Julie M. Jacobsen, Natalia Petersen, Lola Torz, Marina K. Gerstenberg, Kent Pedersen, Søren Østergaard, Birgitte S. Wulff, Birgitte Andersen, Kirsten Raun, Berit Ø. Christoffersen, Linu M. John, Marc L. Reitman, Rune E. Kuhre
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114501- (2024)
Summary: Evaluation of weight loss drugs is usually performed in diet-induced obese mice housed at ∼22°C. This is a cold stress that increases energy expenditure by ∼35% compared to thermoneutrality (∼30°C), which may overestimate drug-induce
Externí odkaz:
https://doaj.org/article/497a3258f3ea4cada07960619cde81b6
Autor:
Linu Mary John, Natalia Petersen, Marina Kjærgaard Gerstenberg, Lola Torz, Kent Pedersen, Berit Østergaard Christoffersen, Rune Ehrenreich Kuhre
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
The impact of ambient housing temperature on the interaction of energy intake, energy expenditure and glycemic control in normal and diet-induced obese mice is examined.
Externí odkaz:
https://doaj.org/article/60aa092aef12437a98ab71722b56afe5
Autor:
Kaare V. Grunddal, Sarah Tonack, Kristoffer L. Egerod, Jonathan James Thompson, Natalia Petersen, Maja S. Engelstoft, Constance Vagne, Céline Keime, Gérard Gradwohl, Stefan Offermanns, Thue W. Schwartz
Publikováno v:
Molecular Metabolism, Vol 51, Iss , Pp 101231- (2021)
Objective: GPR64/ADGRG2 is an orphan Adhesion G protein-coupled receptor (ADGR) known to be mainly expressed in the parathyroid gland and epididymis. This investigation aimed to delineate the cellular expression of GPR64 throughout the body with focu
Externí odkaz:
https://doaj.org/article/7ee8630e8aa2483798aecb86304f3a04
Autor:
Kaare V. Grunddal, Thi A. Diep, Natalia Petersen, Iain R. Tough, Louise J. Skov, Lingzhi Liu, Jesse A. Buijink, Franziska Mende, Chunyu Jin, Sara L. Jepsen, Louis M.E. Sørensen, Michael P. Achiam, Rune B. Strandby, Anders Bach, Bolette Hartmann, Thomas M. Frimurer, Siv A. Hjorth, Michel Bouvier, Helen Cox, Birgitte Holst
Publikováno v:
Molecular Metabolism, Vol 49, Iss , Pp 101207- (2021)
Objectives: Obesity is a complex disease associated with a high risk of comorbidities. Gastric bypass surgery, an invasive procedure with low patient eligibility, is currently the most effective intervention that achieves sustained weight loss. This
Externí odkaz:
https://doaj.org/article/27cbde2769ce433890e3451e70d7b140
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Synthetic glucagon-like peptide-1 (GLP-1) analogues are effective anti-obesity and anti-diabetes drugs. The beneficial actions of GLP-1 go far beyond insulin secretion and appetite, and include cardiovascular benefits and possibly also beneficial eff
Externí odkaz:
https://doaj.org/article/799c69be84d04816aff86ec2416682b3
Autor:
Julie Piccand, Constance Vagne, Florence Blot, Aline Meunier, Anthony Beucher, Perrine Strasser, Mari L. Lund, Sabitri Ghimire, Laure Nivlet, Céline Lapp, Natalia Petersen, Maja S. Engelstoft, Christelle Thibault-Carpentier, Céline Keime, Sara Jimenez Correa, Valérie Schreiber, Nacho Molina, Thue W. Schwartz, Adèle De Arcangelis, Gérard Gradwohl
Publikováno v:
Molecular Metabolism, Vol 29, Iss , Pp 24-39 (2019)
Objective: Enteroendocrine cells (EECs) of the gastro-intestinal tract sense gut luminal factors and release peptide hormones or serotonin (5-HT) to coordinate energy uptake and storage. Our goal is to decipher the gene regulatory networks controllin
Externí odkaz:
https://doaj.org/article/ae5bc94129d345d5a7f7ab5313070cd2
Autor:
Lola J. Torz, Sherri Osborne-Lawrence, Juan Rodriguez, Zhenyan He, María Paula Cornejo, Emilio Román Mustafá, Chunyu Jin, Natalia Petersen, Morten A. Hedegaard, Maja Nybo, Valentina Martínez Damonte, Nathan P. Metzger, Bharath K. Mani, Kevin W. Williams, Jesica Raingo, Mario Perello, Birgitte Holst, Jeffrey M. Zigman
Publikováno v:
Molecular Metabolism, Vol 39, Iss , Pp - (2020)
Objective: Binding of ghrelin to its receptor, growth hormone secretagogue receptor (GHSR), stimulates GH release, induces eating, and increases blood glucose. These processes may also be influenced by constitutive (ghrelin-independent) GHSR activity
Externí odkaz:
https://doaj.org/article/e377e98902394a029b1a044bc11f686a
Autor:
Natalia Petersen, Lola Torz, Kristian H. Reveles Jensen, Gertrud Malene Hjortø, Katja Spiess, Mette Marie Rosenkilde
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
The choroid plexus (CP) plays a major role in controlling the entry of substances and immune cells into the brain as it forms the blood-cerebrospinal fluid barrier (BCSFB) in the brain ventricles. Dysregulated immune cell trafficking through the epit
Externí odkaz:
https://doaj.org/article/dd16803e49bb4ad0b12399dfcd5e77a7
Autor:
Natalia Petersen, Thomas U. Greiner, Lola Torz, Angie Bookout, Marina Kjærgaard Gerstenberg, Carlos M. Castorena, Rune Ehrenreich Kuhre
Publikováno v:
Metabolites, Vol 12, Iss 1, p 39 (2022)
Obesity is caused by prolonged energy surplus. Current anti-obesity medications are mostly centralized around the energy input part of the energy balance equation by increasing satiety and reducing appetite. Our gastrointestinal tract is a key organ
Externí odkaz:
https://doaj.org/article/99ffd87cd8244a898ed0ba5f3c707ec3
Autor:
Kristoffer L. Egerod, Natalia Petersen, Pascal N. Timshel, Jens C. Rekling, Yibing Wang, Qinghua Liu, Thue W. Schwartz, Laurent Gautron
Publikováno v:
Molecular Metabolism, Vol 12, Iss , Pp 62-75 (2018)
Objectives: G protein-coupled receptors (GPCRs) act as transmembrane molecular sensors of neurotransmitters, hormones, nutrients, and metabolites. Because unmyelinated vagal afferents richly innervate the gastrointestinal mucosa, gut-derived molecule
Externí odkaz:
https://doaj.org/article/481cf6923ace4e2c87c2b80e1d6901c5