Validation of the accuracy of the FAST™ score for detecting patients with at-risk nonalcoholic steatohepatitis (NASH) in a North American cohort and comparison to other non-invasive algorithms.

Autor: Tinsay A Woreta, Mark L Van Natta, Mariana Lazo, Arunkumar Krishnan, Brent A Neuschwander-Tetri, Rohit Loomba, Anna Mae Diehl, Manal F Abdelmalek, Naga Chalasani, Samer Gawrieh, Srinivasan Dasarathy, Raj Vuppalanchi, Mohammad S Siddiqui, Kris V Kowdley, Arthur McCullough, Norah A Terrault, Cynthia Behling, David E Kleiner, Mark Fishbein, Paula Hertel, Laura A Wilson, Emily P Mitchell, Laura A Miriel, Jeanne M Clark, James Tonascia, Arun J Sanyal, NASH Clinical Research Network

Publikováno v: PLoS ONE, Vol 17, Iss 4, p e0266859 (2022)

Background and aimsManagement of patients with NASH who are at elevated risk of progressing to complications of cirrhosis (at-risk NASH) would be enhanced by an accurate, noninvasive diagnostic test. The new FAST™ score, a combination of FibroScan�

Externí odkaz: https://doaj.org/article/1833c874d5f54e2e95c2ca91c5a16de6

Validation of the accuracy of the FAST™ score for detecting patients with at-risk nonalcoholic steatohepatitis (NASH) in a North American cohort and comparison to other non-invasive algorithms

Autor: Woreta, Tinsay A, Van Natta, Mark L, Lazo, Mariana, Krishnan, Arunkumar, Neuschwander-Tetri, Brent A, Loomba, Rohit, Mae Diehl, Anna, Abdelmalek, Manal F, Chalasani, Naga, Gawrieh, Samer, Dasarathy, Srinivasan, Vuppalanchi, Raj, Siddiqui, Mohammad S, Kowdley, Kris V, McCullough, Arthur, Terrault, Norah A, Behling, Cynthia, Kleiner, David E, Fishbein, Mark, Hertel, Paula, Wilson, Laura A, Mitchell, Emily P, Miriel, Laura A, Clark, Jeanne M, Tonascia, James, Sanyal, Arun J, NASH Clinical Research Network

Publikováno v: PloS one, vol 17, iss 4

Background and aimsManagement of patients with NASH who are at elevated risk of progressing to complications of cirrhosis (at-risk NASH) would be enhanced by an accurate, noninvasive diagnostic test. The new FAST™ score, a combination of FibroScan�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::86514e6d723182d98a7a0948bb3c7ffa
https://escholarship.org/uc/item/30p411qn

Testosterone is Associated With Nonalcoholic Steatohepatitis and Fibrosis in Premenopausal Women With NAFLD

Autor: Sarkar, Monika A, Suzuki, Ayako, Abdelmalek, Manal F, Yates, Katherine P, Wilson, Laura A, Bass, Nathan M, Gill, Ryan, Cedars, Marcelle, Terrault, Norah, NASH Clinical Research Network

Publikováno v: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol 19, iss 6

Background & aimsHigher testosterone contributes to imaging-confirmed nonalcoholic fatty liver disease (NAFLD) in women, but whether testosterone influences their disease severity is unknown.MethodsThe association of free testosterone (free T) with n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::a4245f426f642d48466b8196500ba2ec
https://escholarship.org/uc/item/56w8n4d8

Multicenter Validation of Association Between Decline in MRI-PDFF and Histologic Response in NASH

Autor: Loomba, Rohit, Neuschwander-Tetri, Brent A, Sanyal, Arun, Chalasani, Naga, Diehl, Anna Mae, Terrault, Norah, Kowdley, Kris, Dasarathy, Srinivasan, Kleiner, David, Behling, Cynthia, Lavine, Joel, Van Natta, Mark, Middleton, Michael, Tonascia, James, Sirlin, Claude, NASH Clinical Research Network

Publikováno v: Hepatology (Baltimore, Md.), vol 72, iss 4

Background and aimsEmerging data from a single-center study suggests that a 30% relative reduction in liver fat content as assessed by magnetic resonance imaging-proton density fat fraction (MRI-PDFF) from baseline may be associated with histologic i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::e5fdda5f2606f7f7838f362bc9d3c207
https://escholarship.org/uc/item/57t3875s

Diagnostic Accuracy of Noninvasive Fibrosis Models to Detect Change in Fibrosis Stage

Autor: Siddiqui, Mohammad Shadab, Yamada, Goro, Vuppalanchi, Raj, Van Natta, Mark, Loomba, Rohit, Guy, Cynthia, Brandman, Danielle, Tonascia, James, Chalasani, Naga, Neuschwander-Tetri, Brent, Sanyal, Arun J, NASH Clinical Research Network

Publikováno v: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol 17, iss 9

Background & aimsNoninvasive methods are needed to determine disease stage in patients with nonalcoholic fatty liver disease (NAFLD). We evaluated the diagnostic performance of several widely available fibrosis models for the assessment of hepatic fi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::40b313a380dccd5a3ed579033a395589
https://escholarship.org/uc/item/81g8h62b