Zobrazeno 1 - 10
of 28
pro vyhledávání: '"NASAL EMBRYONIC LHRH FACTOR"'
Publikováno v:
Journal of Endocrinology. 187:361-368
We report the results of molecular analysis in a series of twelve Kallmann syndrome (KS) and five normosmic hypogonadotropic hypogonadism (nHH) Brazilian patients. Kallman syndrome 1 (KAL-1) gene analysis was performed in all patients and the gonadot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013b17cbed48d1eebb30ca1cf58773fa
https://doi.org/10.1677/joe.1.06103
https://doi.org/10.1677/joe.1.06103
Publikováno v:
Journal of Human Genetics. 49:265-268
As the mouse nasal embryonic LHRH factor gene (Nelf) encodes a guidance molecule for the migration of the olfactory axon and gonadotropin-releasing hormone neurons, its human homolog, NELF, is a candidate gene for Kallmann syndrome, a disease of idio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a5e1c6eeb5d9393b562b4b9a9ee737
https://doi.org/10.1007/s10038-004-0137-4
https://doi.org/10.1007/s10038-004-0137-4
Autor:
Eunkyung Ko, Durkadin Demir, Lawrence C. Layman, Megan E. Sullivan, Samuel D. Quaynor, Richard S. Cameron, Jennifer L. Waller, Hyung Goo Kim, Lynn P. Chorich
Publikováno v:
Molecular and cellular endocrinology. 407
Puberty and reproduction require proper signaling of the hypothalamic-pituitary-gonadal axis controlled by gonadotropin-releasing hormone (GnRH) neurons, which arise in the olfactory placode region and migrate along olfactory axons to the hypothalamu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b0ca4b993b3095b1849cc438028c75
https://pubmed.ncbi.nlm.nih.gov/25731822
https://pubmed.ncbi.nlm.nih.gov/25731822
Akademický článek
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Autor:
Phillip R. Kramer, Susan Wray
Publikováno v:
Gene Expression Patterns. 1:23-26
A novel protein (NELF) was identified screening embryonic luteinizing hormone releasing hormone (LHRH) neurons at different migrational states. Experiments in vitro revealed that NELF functions in olfactory axon outgrowth and subsequently alters LHRH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4bf16f85552c7b8736e69ba3fa71dd
https://doi.org/10.1016/s1567-133x(01)00004-7
https://doi.org/10.1016/s1567-133x(01)00004-7
Autor:
Phillip R. Kramer, Susan Wray
Publikováno v:
Genes & Development. 14:1824-1834
Although a variety of cues have been implicated in axonal targeting during embryogenesis and regeneration, the precise mechanisms guiding olfactory axons remain unclear. Appropriate olfactory axon pathfinding is essential for functional chemoreceptiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be63026baeea77964e66959342f718f3
https://doi.org/10.1101/gad.14.14.1824
https://doi.org/10.1101/gad.14.14.1824
Autor:
Durkadin Demir, Richard S. Cameron, Lynn P. Chorich, Eunkyung Ko, Lindsey Y. Goldberg, Lawrence C. Layman, Samuel D. Quaynor, Hyung Goo Kim, Robert K. Stanley
NELF, a protein identified in migratory GnRH neurons, is predominantly nuclear and alternatively spliced. However, specific NELF splice variants expressed in immortalized GnRH neuronal cell lines from mouse and human are not known. RNA from migratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2683082373894deff0a0ba5e00bf4390
https://europepmc.org/articles/PMC3930684/
https://europepmc.org/articles/PMC3930684/
Autor:
Lawrence C. Layman, Robert S. Podolsky, Wencheng Xiong, Lynn P. Chorich, Lisa M. Halvorson, Hyung Goo Kim, Richard S. Cameron, Balasubramanian Bhagavath, Puttur D. Prasad, Ning Xu
Nasal embryonic LHRH factor (NELF) has been hypothesized to participate in the migration of GnRH and olfactory neurons into the forebrain, a prerequisite for normal hypothalamic-pituitary-gonadal function in puberty and reproduction. However, the bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d1a6e45ba379e18674596042086127
https://europepmc.org/articles/PMC3437992/
https://europepmc.org/articles/PMC3437992/
Publikováno v:
Protein Science.
A cysteine protease domain (CPD) has been recently discovered in a group of multifunctional, autoprocessing RTX toxins (MARTX) and Clostridium difficile toxins A and B. These CPDs (referred to as CPDmartx) autocleave the toxins to release domains wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f23ee838351210aeda66d760ccbe34
https://doi.org/10.1002/pro.78
https://doi.org/10.1002/pro.78
Autor:
Ori Palevitch, Natalya Borodovsky, Yoav Gothilf, Yonathan Zohar, Eytan Abraham, Gil Levkowitz
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 238(1)
The initiation of puberty and the functioning of the reproductive system depend on proper development of the hypophysiotropic gonadotropin-releasing hormone (GnRH) system. One critical step in this process is the embryonic migration of GnRH neurons f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc981182a109b4115a82640bee86fcb
https://pubmed.ncbi.nlm.nih.gov/19097186
https://pubmed.ncbi.nlm.nih.gov/19097186