Zobrazeno 1 - 10
of 203
pro vyhledávání: '"NAOKO KUMAGAI"'
Autor:
Yurika Shimizu, Srinivas Bandaru, Mari Hara, Sonny Young, Toshikazu Sano, Kaya Usami, Yuta Kurano, Suni Lee, Naoko Kumagai-Takei, Shogo Takashiba, Shunji Sano, Tatsuo Ito
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract We herein elucidate the function of SARS-CoV-2derived 5'UTR in the human cells. 5'UTR bound host cellular RNAs were immunoprecipitated by gRNA-dCas13 (targeting luciferase RNA fused to SARS-CoV-2 5'UTR) in HEK293T and A549 cells. The 5'UTR b
Externí odkaz:
https://doaj.org/article/74a39e0b38cd409fbd809668c1fe9304
Autor:
Naoko Kumagai-Takei, Yasumitsu Nishimura, Hidenori Matsuzaki, Suni Lee, Kei Yoshitome, Tatsuo Ito, Takemi Otsuki
Publikováno v:
Environmental Health and Preventive Medicine, Vol 26, Iss 1, Pp 1-11 (2021)
Abstract Background Asbestos fibers possess tumorigenicity and are thought to cause mesothelioma. We have previously reported that exposure to asbestos fibers causes a reduction in antitumor immunity. Asbestos exposure in the mixed lymphocyte reactio
Externí odkaz:
https://doaj.org/article/49365d1514d34c35bf94f66d165f8a3e
Autor:
Naoko Kumagai-Takei, Yasumitsu Nishimura, Megumi Maeda, Hiroaki Hayashi, Hidenori Matsuzaki, Suni Lee, Kei Yoshitome, Tatsuo Ito, Takemi Otsuki
Publikováno v:
Environmental Health and Preventive Medicine, Vol 25, Iss 1, Pp 1-6 (2020)
Abstract Asbestos exposure is known to cause malignant mesothelioma, which is associated with poor prognosis. We focused on and examined the effect of asbestos exposure on the differentiation and function of cytotoxic T lymphocytes (CTLs). CTLs have
Externí odkaz:
https://doaj.org/article/d6f0a282eb264d0192fb1728d323db61
Autor:
Shoko Yamamoto, Suni Lee, Hidenori Matsuzaki, Naoko Kumagai-Takei, Kei Yoshitome, Nagisa Sada, Yurika Shimizu, Tastsuo Ito, Yasumitsu Nishimura, Takemi Otsuki
Publikováno v:
Environment International, Vol 138, Iss , Pp - (2020)
The effects of asbestos fibers on human immune cells have not been well documented. We have developed a continuously exposed cell line model using the human T-lymphotropic virus 1 (HTLV-1)-immortalized human T cell line MT-2. Sublines continuously ex
Externí odkaz:
https://doaj.org/article/f14e27cb8bb54d3aa4f6b0ea82ef93f3
Autor:
Hidenori Matsuzaki, Naoko Kumagai-Takei, Suni Lee, Megumi Maeda, Nagisa Sada, Tamayo Hatayama, Shoko Yamamoto, Miho Ikeda, Kei Yoshitome, Yu Min, Yasumitsu Nishimura, Takemi Otsuki
Publikováno v:
Environmental Health and Preventive Medicine, Vol 22, Iss 1, Pp 1-7 (2017)
Abstract The immunological effects of asbestos exposure on various lymphocytes such as the regulatory T cell (Treg), responder CD4+ T helper cell (Tresp), CD8+ cytotoxic T lymphocytes (CTL), and natural killer (NK) cells were investigated. Results sh
Externí odkaz:
https://doaj.org/article/f1c2aa9eabdd4cfb99c4f6a36e38b06f
Autor:
Naoko Kumagai-Takei, Suni Lee, Bandaru Srinivas, Yurika Shimizu, Nagisa Sada, Kei Yoshitome, Tatsuo Ito, Yasumitsu Nishimura, Takemi Otsuki
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 6987 (2020)
Asbestos exposure causes malignant tumors such as lung cancer and malignant mesothelioma. The effects of asbestos fibers on immunocompetent cells, however, have not been well studied. Asbestos physically comprises a fibrous substance, which differs f
Externí odkaz:
https://doaj.org/article/69f4e942bd374b74af6b398014751589
Autor:
Naoko Kumagai-Takei, Yasumitsu Nishimura, Hidenori Matsuzaki, Suni Lee, Kei Yoshitome, Takemi Otsuki
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Although the tumorigenicity of asbestos, which is thought to cause mesothelioma, has been clarified, its effect on antitumor immunity requires further investigation. We previously reported a decrease in the percentage of perforin+ cells of stimulated
Externí odkaz:
https://doaj.org/article/ff033445c8ad4574979b37d5d5f3b632
Autor:
Suni Lee, Machiko Honda, Shoko Yamamoto, Naoko Kumagai-Takei, Kei Yoshitome, Yasumitsu Nishimura, Nagisa Sada, Shigeyuki Kon, Takemi Otsuki
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2581 (2019)
Silicosis is a typical form of pneumoconiosis and is characterized as a type of lung fibrosis. Silica particles are captured and recognized upon by alveolar macrophages via the macrophage receptor with collagenous structure (MARCO) scavenger receptor
Externí odkaz:
https://doaj.org/article/f725cdc1645548b9bc2869bbc6961790
Autor:
Masamitsu Kurakazu, Taeko Ueda, Kunihiro Matsuo, Hiroyasu Ishikura, Naoko Kumagai, Toshiyuki Yoshizato, Shingo Miyamoto
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 51, Iss 4, Pp 639-642 (2012)
Objective: Acute pulmonary thromboembolism (PTE) is a common illness that causes death and disability. Deep vein thrombosis (DVT) is often found in patients with a large myomatous uterus, and can occasionally result in acute PTE. Here, we describe th
Externí odkaz:
https://doaj.org/article/18d9377893134df6ae0dce3c3a0cfc91
Autor:
Naoko Kumagai-Takei, Yasumitsu Nishimura, Hidenori Matsuzaki, Suni Lee, Kei Yoshitome, Hiroaki Hayashi, Takemi Otsuki
Publikováno v:
Journal of Immunology Research, Vol 2016 (2016)
We previously reported that exposure to chrysotile B (CB) asbestos suppressed the induction of mature cytotoxic T lymphocytes (CTLs) during mixed lymphocyte reaction assays (MLRs) with a decrease in the proliferation of immature CTLs. However, the me
Externí odkaz:
https://doaj.org/article/5c50b7f62de34d959b969e05c536d1f4