Zobrazeno 1 - 10
of 503
pro vyhledávání: '"NAMASIVAYAM AMBALAVANAN"'
Autor:
Teodora Nicola, Nancy Wenger, Xin Xu, Michael Evans, Luhua Qiao, Gabriel Rezonzew, Youfeng Yang, Tamas Jilling, Camilla Margaroli, Kristopher Genschmer, Kent Willis, Namasivayam Ambalavanan, J. Edwin Blalock, Amit Gaggar, Charitharth Vivek Lal
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Bronchopulmonary dysplasia (BPD) is a chronic lung disease of prematurity. Exposure to noxious stimuli such as hyperoxia, volutrauma, and infection in infancy can have long-reaching impacts on lung health and predispose towards the developme
Externí odkaz:
https://doaj.org/article/194ba58ce72542aaab48a844418a8020
Autor:
William E. King, Urvi Jhaveri Sanghvi, Namasivayam Ambalavanan, Vivek V. Shukla, Colm P. Travers, Robert L. Schelonka, Clyde Wright, Waldemar A. Carlo
Publikováno v:
ERJ Open Research, Vol 10, Iss 4 (2024)
Background The Neonatal Oxygenation Prospective Meta-analysis found that in infants
Externí odkaz:
https://doaj.org/article/aa925842f9ab41c2ace3892108e5519a
Autor:
Ahmed Abdelgawad, Teodora Nicola, Isaac Martin, Brian A. Halloran, Kosuke Tanaka, Comfort Y. Adegboye, Pankaj Jain, Changchun Ren, Charitharth V. Lal, Namasivayam Ambalavanan, Amy E. O’Connell, Tamás Jilling, Kent A. Willis
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Background Mammalian mucosal barriers secrete antimicrobial peptides (AMPs) as critical, host-derived regulators of the microbiota. However, mechanisms that support microbiota homeostasis in response to inflammatory stimuli, such as supraphy
Externí odkaz:
https://doaj.org/article/f4008e535d694a91ab608755c7261389
Autor:
Snehashis Hazra, Rui Li, Bianca M. Vamesu, Tamas Jilling, Scott W. Ballinger, Namasivayam Ambalavanan, Jegen Kandasamy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Oxidant stress contributes significantly to the pathogenesis of bronchopulmonary dysplasia (BPD) in extremely low birth weight (ELBW) infants. Mitochondrial function regulates oxidant stress responses as well as pluripotency and regenerative
Externí odkaz:
https://doaj.org/article/1e7771b5edd04ed59328663ace9ab697
Autor:
Nancy M. Wenger, Luhua Qiao, Teodora Nicola, Zoha Nizami, Isaac Martin, Brian A. Halloran, Kosuke Tanaka, Michael Evans, Xin Xu, Timothy G. Dinan, Charles Kakilla, Gillian DunnGalvin, Namasivayam Ambalavanan, Kent A. Willis, Amit Gaggar, Charitharth Vivek Lal
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
IntroductionDysbiosis of the gut microbiome may augment lung disease via the gut-lung axis. Proteobacteria may contribute to tissue proteolysis followed by neutrophil recruitment, lung tissue injury, and perpetuation of chronic inflammation. To study
Externí odkaz:
https://doaj.org/article/d74b1c86a43c49bba760c2f43a762a1b
Autor:
Bianca M. Vamesu, Teodora Nicola, Rui Li, Snehashis Hazra, Sadis Matalon, Naftali Kaminski, Namasivayam Ambalavanan, Jegen Kandasamy
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
Mitochondrial dysfunction at birth predicts bronchopulmonary dysplasia (BPD) in extremely low–birth weight (ELBW) infants. Recently, nebulized thyroid hormone (TH), given as triiodothyronine (T3), was noted to decrease pulmonary fibrosis in adult a
Externí odkaz:
https://doaj.org/article/b65d672df1644734b806a25b8476725b
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
BackgroundOxygen supplementation is commonly used to maintain oxygen saturation (SpO2) levels in preterm infants within target ranges to reduce intermittent hypoxemic (IH) events, which are associated with short- and long-term morbidities. There is n
Externí odkaz:
https://doaj.org/article/bce23122d2d048039ac9b73aa89f1236
Autor:
Amelia Freeman, Luhua Qiao, Nelida Olave, Gabriel Rezonzew, Samuel Gentle, Brian Halloran, Gloria S. Pryhuber, Amit Gaggar, Trent E. Tipple, Namasivayam Ambalavanan, Charitharth Vivek Lal
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Background MicroRNA (miR) are small conserved RNA that regulate gene expression post-transcription. Previous genome-wide analysis studies in preterm infants indicate that pathways of miR 219-5p are important in infants with Bronchopulmonary
Externí odkaz:
https://doaj.org/article/a77a493e93a84952b8f9d5217a92c176
Autor:
Robert P. Richter, Gregory A. Payne, Namasivayam Ambalavanan, Amit Gaggar, Jillian R. Richter
Publikováno v:
Matrix Biology Plus, Vol 14, Iss , Pp 100106- (2022)
The vascular endothelium is the interface between circulating blood and end organs and thus has a critical role in preserving organ function. The endothelium is lined by a glycan-rich glycocalyx that uniquely contributes to endothelial function throu
Externí odkaz:
https://doaj.org/article/1aeae2cd1a314c989f7309dc5a7429f6
Autor:
Samuel J. Gentle, Amelia Freeman, Rakesh P. Patel, Namasivayam Ambalavanan, Charitharth V. Lal
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-4 (2020)
Abstract Rationale Bronchopulmonary dysplasia (BPD) is the most common complication of prematurity and significantly contributes to mortality and morbidity with few predictive biomarkers. Given that nitrites have been implicated in pathways associate
Externí odkaz:
https://doaj.org/article/bd972193beef48c89231c78f24cf01f4