Zobrazeno 1 - 10
of 632
pro vyhledávání: '"NAM JIN YOO"'
Publikováno v:
Polish Journal of Pathology, Vol 68, Iss 3, Pp 258-260 (2017)
Both CUX1 and SIRT1 are considered tumor suppressor genes (TSGs), but it is not known whether CUX1 and SIRT1 alterations are different between high microsatellite instability (MSI-H) and microsatellite stable MSI (MSS) cancers. We identified frameshi
Externí odkaz:
https://doaj.org/article/3372ba94d0dc412fa43c2f53caebbb22
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 30:e16-e20
Deregulations of DNA-methylation-related genes are common in cancers, but frameshift mutation status in colon cancer (CC) is unknown. Our study aims to assess whether CTCF, ZFP57, and ATF7IP genes in this category are mutated in CC. CTCF, ZFP57, and
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 29:570-575
ZMYM4 is a zinc finger protein, whose cancer-related functions are partially known (cell shape maintenance and cell death). In this study, we analyzed 4 sites of mononucleotide repeats in the coding sequence of ZMYM4 in gastric (GC) and colonic cance
Publikováno v:
Pathology & Oncology Research. 26:1983-1987
Tight junction and gap junction are major cell junctions that play important roles in cellular communication and structural integrity. Alterations of these junctions are known to be involved in cancer pathogenesis. Claudins and connexins are major ti
Autor:
Jae Woong, Kim, Seong Won, Moon, Ha Yoon, Mo, Hyun Ji, Son, Eun Ji, Choi, Nam Jin, Yoo, Chang Hyeok, Ann, Sug Hyung, Lee
Publikováno v:
Pathology - Research and Practice. 241:154288
Microsatellite instability-high (MSI-H) colorectal cancer (CRC) is different from microsatellite stable (MSS) CRC concerning biological, and clinical features. In MSI-H CRCs, defects of mismatch repair genes produce increased mutation accumulation in
Publikováno v:
Cancer Biomarkers. 24:1-6
Background Both QKI and TMEFF2 genes are considered putative tumor suppressor genes (TSGs). In gastric (GC) and colorectal (CRC) cancers, downregulation of their expressions is known to be frequent. However, QKI and TMEFF2 mutations that could potent
Publikováno v:
Pathology and Oncology Research. 27
Nucleotide-binding and leucine-rich repeat protein (NLRP) genes are involved in inflammasome formation that plays a role in inflammation/host defense and cell death. Both cell death and inflammation are crucial for cancer development, but the roles o
Publikováno v:
Pathology and Oncology Research
TRAF2 and TRAF3 genes of tumor necrosis factor receptor (TNF-R)-associated factor (TRAF) family are involved in diverse cell signaling, and function as both tumor suppressor gene and oncogene. Alterations of TRAF2 and TRAF3 in colon cancer (CC) along
Publikováno v:
Pathology, research and practice. 219
Epigenetic dysregulation is a hallmark of cancers, and examples of its cancer-associated expression and mutation alterations are rapidly growing. Histone methylation, a process by which methyl groups are transferred to amino acids of histone proteins
Publikováno v:
Pathology and Oncology Research
Nucleotide-binding and leucine-rich repeat protein (NLRP) genes are involved in inflammasome formation that plays a role in inflammation/host defense and cell death. Both cell death and inflammation are crucial for cancer development, but the roles o