Zobrazeno 1 - 10
of 24
pro vyhledávání: '"NADPH, nicotinamide adenine dinucleotide phosphate reduced"'
Autor:
Oluwafunke A. Ajayi, Moses C. Antiya, Dorcas Ibukun Akinloye, Adio Jamiu Akamo, Samuel O. Faseun, Gogonte Hezekiah Amah, O E Eteng, O. O. Adeleye, Regina Ngozi Ugbaja, Oluwatosin A. Dosumu
Publikováno v:
Toxicology Reports, Vol 8, Iss, Pp 1803-1813 (2021)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • Naringin inhibits and/or scavenge in vitro free radicals. • Exposure to cyclophosphamide (CYCP) invoked erythrocytotoxicity. • Erythrocytotoxicity was characterized by oxidative stress and dyslipidaemia. •
Highlights • Naringin inhibits and/or scavenge in vitro free radicals. • Exposure to cyclophosphamide (CYCP) invoked erythrocytotoxicity. • Erythrocytotoxicity was characterized by oxidative stress and dyslipidaemia. •
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638b70b3cd7e017a33c222630706c3f1
http://www.sciencedirect.com/science/article/pii/S2214750021001839
http://www.sciencedirect.com/science/article/pii/S2214750021001839
Autor:
Cristiano Rumio, Fabrizio Marcucci
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 2, Pp 234-245 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 2, Pp 234-245 (2021)
Tumor cells often switch from mitochondrial oxidative metabolism to glycolytic metabolism even under aerobic conditions. Tumor cell glycolysis is accompanied by several nonenzymatic activities among which induction of drug resistance has important th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa5b30ce2ee01dd517b432844e879a6
http://europepmc.org/articles/PMC7804361
http://europepmc.org/articles/PMC7804361
Publikováno v:
Biochemical Pharmacology
Graphical abstract
COVID-19 is an ongoing viral pandemic disease that is caused by SARS-CoV2, inducing severe pneumonia in humans. However, several classes of repurposed drugs have been recommended, no specific vaccines or effective therapeutic
COVID-19 is an ongoing viral pandemic disease that is caused by SARS-CoV2, inducing severe pneumonia in humans. However, several classes of repurposed drugs have been recommended, no specific vaccines or effective therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3288262888c0c58d8afaae1b90afb12
http://europepmc.org/articles/PMC7250789
http://europepmc.org/articles/PMC7250789
Autor:
Monica Raicu, Maya Simionescu, Mihaela-Loredana Antonescu, Ioana Madalina Fenyo, Simona-Adriana Manea, Adrian Manea
Publikováno v:
Redox Biology
Redox Biology, Vol 16, Iss, Pp 332-343 (2018)
Redox Biology, Vol 16, Iss, Pp 332-343 (2018)
Reactive oxygen species (ROS) generated by up-regulated NADPH oxidase (Nox) contribute to structural-functional alterations of the vascular wall in diabetes. Epigenetic mechanisms, such as histone acetylation, emerged as important regulators of gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78bd5bc3b6c199e70a5e710bd225dcc
https://doi.org/10.1016/j.redox.2018.03.011
https://doi.org/10.1016/j.redox.2018.03.011
Publikováno v:
Toxicology Reports, Vol 3, Iss, Pp 328-335 (2016)
Toxicology Reports
Scipedia Open Access
Scipedia SL
Toxicology Reports
Scipedia Open Access
Scipedia SL
Highlights • NSO improves the endogenous antioxidant status and metabolic activity of liver. • NSO protects the liver against CP generated free radical attack. • Oral administration of NSO ameliorates the hepatotoxicity induced by CP treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea624bcaebe73c01ca7d96f5af8012e
http://www.sciencedirect.com/science/article/pii/S2214750016300178
http://www.sciencedirect.com/science/article/pii/S2214750016300178
Autor:
Horia Muresian, Adrian Manea, A.G. Lazar, Mihaela-Loredana Vlad, Maya Simionescu, Ioana Madalina Fenyo, Simona-Adriana Manea, Monica Raicu
Publikováno v:
Redox Biology, Vol 28, Iss, Pp-(2020)
Redox Biology
Redox Biology
NADPH oxidase (Nox)-derived reactive oxygen species (ROS) are instrumental in all inflammatory phases of atherosclerosis. Dysregulated histone deacetylase (HDAC)-related epigenetic pathways have been mechanistically linked to alterations in gene expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61e6e5181ae1d85fd82cbad6ec18bd5
https://doi.org/10.1016/j.redox.2019.101338
https://doi.org/10.1016/j.redox.2019.101338
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 6, Iss, Pp 389-394 (2019)
Toxicology Reports, Vol 6, Iss, Pp 389-394 (2019)
Highlights • Indomethacin (IndoM) administration causes renal, hepatic and intestinal toxicity. • The renal proximal tubule, intestinal mucosa particularly their BBM and liver seem to be the major IndoM targets. • IndoM produces multiple advers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81fbc24c449fc3d94181ca322213788
https://pubmed.ncbi.nlm.nih.gov/31080746
https://pubmed.ncbi.nlm.nih.gov/31080746
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 2, Iss C, Pp 806-816 (2015)
Toxicology Reports, Vol 2, Iss C, Pp 806-816 (2015)
Terminalia arjuna is a tree having an extensive medicinal potential in cardiovascular disorders. Triterpenoids are mainly responsible for cardiovascular properties. Alcoholic and aqueous bark extracts of T. arjuna, arjunic acid, arjunetin and arjunge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d60f51eb13950547b45ea2d09cf1735
https://doi.org/10.1016/j.toxrep.2015.02.008
https://doi.org/10.1016/j.toxrep.2015.02.008
Autor:
Christin Peters, Uwe T. Bornscheuer, Florian Rudroff, Marko D. Mihovilovic, Nikolin Oberleitner
Publikováno v:
Journal of Biotechnology
Highlights • We compared an enzyme cascade in vivo as well as in vitro. • Mechanistic insights were gained for the presented cascade. • Monomer production for biorenewable polyesters was investigated. • Pathway construction with non-related e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055d3b51d5da6e0c33a266e30edc8509
https://doi.org/10.1016/j.jbiotec.2014.04.008
https://doi.org/10.1016/j.jbiotec.2014.04.008
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 795-802 (2014)
Redox Biology
Redox Biology
Regular consumption of moderate doses of wine is an integral part of the Mediterranean diet, which has long been considered to provide remarkable health benefits. Wine׳s beneficial effect has been attributed principally to its non-alcoholic portion,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6312be27d09caa31aabbf9dbf747ced6
http://www.sciencedirect.com/science/article/pii/S2213231714000809
http://www.sciencedirect.com/science/article/pii/S2213231714000809