Zobrazeno 1 - 10
of 81
pro vyhledávání: '"NAD+ biosynthesis"'
Publikováno v:
Pathology and Oncology Research, Vol 29 (2023)
The growing evidence implies that tumor cells need to increase NAD+ levels by upregulating NAD+ biosynthesis to satisfy their growth demand. NAD+ biosynthesis metabolism is implicated in tumor progression. Breast cancer (BC) is the most common malign
Externí odkaz:
https://doaj.org/article/1f24ee6cc17948a7bf4735a0cba25416
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
IntroductionQuinolinic acid is an intermediate compound derived from the metabolism of dietary tryptophan. Its accumulation has been reported in patients suffering a broad spectrum of diseases and conditions. In this manuscript, we present the result
Externí odkaz:
https://doaj.org/article/70372c9bb5884761b8fd847a4b07cfba
Akademický článek
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Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-10 (2020)
Abstract Background Noncanonical redox cofactors are emerging as important tools in cell-free biosynthesis to increase the economic viability, to enable exquisite control, and to expand the range of chemistries accessible. However, these noncanonical
Externí odkaz:
https://doaj.org/article/059e1432ed6a4f7d8aa8d11087e351e2
Autor:
Gabriele Minazzato, Elisa Marangoni, Carlo Fortunato, Riccardo Petrelli, Loredana Cappellacci, Fabio Del Bello, Leonardo Sorci, Massimiliano Gasparrini, Francesco Piacente, Santina Bruzzone, Nadia Raffaelli
Publikováno v:
Molecules, Vol 28, Iss 3, p 961 (2023)
The maintenance of a proper NAD+ pool is essential for cell survival, and tumor cells are particularly sensitive to changes in coenzyme levels. In this view, the inhibition of NAD+ biosynthesis is considered a promising therapeutic approach. Current
Externí odkaz:
https://doaj.org/article/f234e71ecbca48c09d5f4681ae107005
Publikováno v:
Metabolites, Vol 13, Iss 1, p 103 (2023)
Feeding thermally oxidized lipids to pigs has been shown to compromise growth and health, reduce energy digestibility, and disrupt lipid metabolism. However, the effects of feeding oxidized lipids on amino acid metabolism in pigs have not been well d
Externí odkaz:
https://doaj.org/article/4d63449ddc414ffcbf8fe47373b95ade
Autor:
Yong Ding, Xinli Li, Geoff P. Horsman, Pengwei Li, Min Wang, Jine Li, Zhilong Zhang, Weifeng Liu, Bian Wu, Yong Tao, Yihua Chen
Publikováno v:
Advanced Science, Vol 8, Iss 9, Pp n/a-n/a (2021)
Abstract Nicotinamide adenine dinucleotide (NAD+) is a life essential molecule involved in versatile biological processes. To date, only two de novo biosynthetic routes to NAD+ are described, both of which start from a proteinogenic amino acid and ar
Externí odkaz:
https://doaj.org/article/7c65560618944b09848626d4f5994e7e
Publikováno v:
Antioxidants, Vol 11, Iss 3, p 541 (2022)
High-fat diet (HFD)-induced vascular impairment in mice is associated with a dysfunction of the perivascular adipose tissue (PVAT). The present study was conducted to investigate the involvement of sirtuin 1 (SIRT1). Male C57BL/6J mice were fed an HF
Externí odkaz:
https://doaj.org/article/6598ffc95c484149b1acff1ac68bafde
Akademický článek
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Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Plant pathogenic fungi are a major threat to food security and impose a severe economic burden, thus there is a continuous need to develop new strategies to manage them. NAD+ is a co-factor in numerous enzymatic activities and determines the metaboli
Externí odkaz:
https://doaj.org/article/6d68fdaccdf94addae9516383fe60762