Use of an anti-pan T-lymphocyte ricin a chain immunotoxin in steroid- resistant acute graft-versus-host disease

Autor: VS Byers, PJ Henslee, NA Kernan, BR Blazar, R Gingrich, GL Phillips, CF LeMaistre, G Gilliland, JH Antin, P Martin

Publikováno v: Blood. 75:1426-1432

Acute steroid-resistant graft-versus-host disease (AGVHD) after allogeneic bone marrow transplantation is frequently fatal. A new treatment for this T-lymphocyte-mediated condition uses an immunotoxin, H65-RTA, comprised of a monoclonal antibody that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6c37708a5aa36f5ef7f12432ce0225c
https://doi.org/10.1182/blood.v75.7.1426.bloodjournal7571426

Clonable T lymphocytes in T cell-depleted bone marrow transplants correlate with development of graft-v-host disease

Autor: NA Kernan, NH Collins, L Juliano, T Cartagena, B Dupont, RJ O'Reilly

Publikováno v: Blood. 68:770-773

Early clinical trials using T lymphocyte-depleted human marrow for transplantation have reported that such grafts reduce, to varying degrees, both the incidence and the severity of graft-v-host disease (GVHD). However, to date, no clear estimates hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5dca18cf68509fdbf6d034af1f563135
https://doi.org/10.1182/blood.v68.3.770.bloodjournal683770

Craniospinal irradiation and/or intraventricular radioimmunotherapy after high-dose chemotherapy and autologous stem cell rescue in patients with CNS retinoblastoma-Safety and outcomes.

Autor: Sait SF; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA.; Pediatric Neuro-Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Kernan NA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Pediatric Stem Cell Transplantation and Cell Therapy Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Klein E; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Spitzer B; Division of Hematology/Oncology, Department of Pediatrics, Hackensack University Medical Center, Hackensack, New Jersey, USA., Levy CF; Division of Hematology/Oncology and Cellular Therapy, Department of Pediatrics, Cohen Children's Medical Center, New Hyde Park, New York, USA.; Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA., Fish J; Division of Hematology/Oncology and Cellular Therapy, Department of Pediatrics, Cohen Children's Medical Center, New Hyde Park, New York, USA.; Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA., Yildirim O; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Haque S; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Donzelli M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Bernot MR; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Abramson DH; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Francis JH; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Khakoo Y; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA.; Pediatric Neuro-Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Division of Child Neurology, Department of Pediatrics, and Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Karajannis M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA.; Pediatric Neuro-Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Sands S; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Pandit-Taskar N; Department of Nuclear Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Wolden S; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Kramer K; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA., Dunkel IJ; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA.; Pediatric Neuro-Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

Publikováno v: Pediatric blood & cancer [Pediatr Blood Cancer] 2024 Nov; Vol. 71 (11), pp. e31297. Date of Electronic Publication: 2024 Aug 31.

Impact of rabbit anti-thymocyte globulin (ATG) exposure on outcomes after ex vivo T-cell-depleted hematopoietic cell transplantation in pediatric and young adult patients.

Autor: Lakkaraja M; Fred Hutchinson Cancer Center, Seattle, Washington, USA; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA., Mauguen A; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Boulad F; Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Cancio MI; Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA., Curran KJ; Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA., Harris AC; Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA., Kernan NA; Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Klein E; Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Kung AL; Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Oved J; Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA., Prockop S; Dana Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Scaradavou A; Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA., Spitzer B; Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA., O'Reilly RJ; Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA., Boelens JJ; Department of Pediatrics, BMT Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA; Department of Pediatrics, Weill Cornell Medicine, New York, New York, USA. Electronic address: boelensj@mskcc.org.

Publikováno v: Cytotherapy [Cytotherapy] 2024 Apr; Vol. 26 (4), pp. 351-359. Date of Electronic Publication: 2024 Feb 12.

Association between busulfan exposure and survival in patients undergoing a CD34+ selected stem cell transplantation.

Autor: Tamari R; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Scordo M; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Kunvarjee BM; Department of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, NY., Proli A; Flatiron Health, New York, NY., Lin A; Department of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, NY., Flynn J; Department of Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY., Cho C; Stem Cell Transplantion and Cellular Therapy Program, John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ., Devlin S; Department of Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY., Klein E; Department of Pediatrics, Stem Cell Transplantation and Cellular Therapies Service, Memorial Sloan Kettering Cancer Center, New York, NY., Boulad F; Department of Pediatrics, Stem Cell Transplantation and Cellular Therapies Service, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Pediatrics, Weill Cornell Medicine, New York, NY., Cancio MI; Department of Pediatrics, Stem Cell Transplantation and Cellular Therapies Service, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Pediatrics, Weill Cornell Medicine, New York, NY., Curran KJ; Department of Pediatrics, Stem Cell Transplantation and Cellular Therapies Service, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Pediatrics, Weill Cornell Medicine, New York, NY., Jakubowski AA; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Kernan NA; Department of Pediatrics, Stem Cell Transplantation and Cellular Therapies Service, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Pediatrics, Weill Cornell Medicine, New York, NY., Kung AL; Department of Pediatrics, Stem Cell Transplantation and Cellular Therapies Service, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Pediatrics, Weill Cornell Medicine, New York, NY., O'Reilly RJ; Department of Pediatrics, Stem Cell Transplantation and Cellular Therapies Service, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Pediatrics, Weill Cornell Medicine, New York, NY., Papadopoulos EB; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Prockop S; Department of Pediatrics, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA., Scaradavou A; Department of Pediatrics, Stem Cell Transplantation and Cellular Therapies Service, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Pediatrics, Weill Cornell Medicine, New York, NY., Shaffer BC; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Shah G; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Spitzer B; Department of Pediatrics, Stem Cell Transplantation and Cellular Therapies Service, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Pediatrics, Weill Cornell Medicine, New York, NY., Gyurkocza B; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Giralt SA; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Perales MA; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Medicine, Weill Cornell Medical College, New York, NY., Boelens JJ; Department of Pediatrics, Stem Cell Transplantation and Cellular Therapies Service, Memorial Sloan Kettering Cancer Center, New York, NY.; Department of Pediatrics, Weill Cornell Medicine, New York, NY.

Publikováno v: Blood advances [Blood Adv] 2023 Sep 26; Vol. 7 (18), pp. 5225-5233.