Zobrazeno 1 - 10
of 94
pro vyhledávání: '"N6-methyladenosine (m6A) modification"'
Autor:
Bin Peng, Yinglin Lin, Gao Yi, Mingzhen Lin, Yao Xiao, Yezhenghong Qiu, Wenxia Yao, Xinke Zhou, Zhaoyu Liu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract The epigenetic regulation of N6-methyladenosine (m6A) has attracted considerable interest in tumor research, but the potential roles of m6A regulator-related genes, remain largely unknown within the context of gastric cancer (GC) and tumor m
Externí odkaz:
https://doaj.org/article/3965a63e12bc4e6eb94a127f2baceff7
Autor:
Qiao‐Ru Guo, Guo‐Bin Zhang, Wen‐Min Zhou, Yu Lu, Xin‐Zhu Chen, Zhuo‐Fen Deng, Jin‐Shuo Li, Hong Bi, Ming‐Sheng Wu, Ming‐Ran Xie, Yan‐Yan Yan, Jian‐Ye Zhang
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Cancer is a disease with molecular heterogeneity that is closely related to gene mutations and epigenetic changes. The principal histological subtype of lung cancer is non‐small cell lung cancer (NSCLC). Long noncoding RNA (lncRNA) is a ki
Externí odkaz:
https://doaj.org/article/338197b238784460b8f2ba42ec1bd2f8
Autor:
Yue Yang, Xinwei Guo, Chenyan Huang, Chen Chen, Yingying Zhou, Zhengrong Gao, Chuanliang Feng, Shengjie Jiang, Xuliang Deng, Yan Wei
Publikováno v:
Small Structures, Vol 5, Iss 5, Pp n/a-n/a (2024)
Chirality, a fundamental design feature at all levels of life organization, has shown great capability in guiding cell‐fate determination and tissue regeneration. Chirality‐directed differentiation programs involve remarkable changes in transcrip
Externí odkaz:
https://doaj.org/article/6ba955971245427c91b353d550c0fdfd
Autor:
Chao Wu, Xin Yu, Xiaoling Li, Ran An, Shengnan Li, Xinyue Liu, Xiangting Hu, Shufei Li, Qinghong Zhou, Limei Li, Hai Yu, Miao Zhao, Antao Chang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 276, Iss , Pp 116302- (2024)
Benzene is a known contributor to human leukaemia through its toxic effects on bone marrow cells, and epigenetic modification is believed to be a potential mechanism underlying benzene pathogenesis. However, the specific roles of N6-methyladenosine (
Externí odkaz:
https://doaj.org/article/6293e93e4ec04f69904a66ff984319ec
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Liver cancer remains as the third leading cause of cancer-related death globally as of 2020. Despite the significant progress made in the field of liver cancer treatment, there is still a lack of effective therapies in patients with advanced cancer a
Externí odkaz:
https://doaj.org/article/1a8a4003e2894d9f8035de6427b72e8f
Publikováno v:
Biomolecules & Biomedicine (2023)
Mitochondrial dysfunction is an important pathogenic factor in non-alcoholic fatty liver disease (NAFLD). Methyltransferase-like 14 (METTL14) has been implicated in mitochondrial fission processes. This research aimed to investigate the mechanism of
Externí odkaz:
https://doaj.org/article/d25c2ae9579a47cfa7d88a05ba005d7d
Publikováno v:
Cells, Vol 13, Iss 1, p 66 (2023)
Reversible N6-adenosine methylation of mRNA, referred to as m6A modification, has emerged as an important regulator of post-transcriptional RNA processing. Numerous studies have highlighted its crucial role in the pathogenesis of diverse diseases, pa
Externí odkaz:
https://doaj.org/article/02395f952beb4b79baaf82cf938a0e59
Akademický článek
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Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 4, Pp 385-397 (2022)
Growing evidence supports that cancer progression is closely associated with the tumor microenvironment and immune evasion. Importantly, recent studies have revealed the crucial roles of epigenetic regulators in shaping the tumor microenvironment and
Externí odkaz:
https://doaj.org/article/f754e06c35f44d79b1bffa6440b75937
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Background N6-methyladenosine (m6A) has emerged as a significant regulator of the progress of various cancers. However, its role in lung adenocarcinoma (LUAD) remains unclear. Here, we explored the biological function and underlying mechanis
Externí odkaz:
https://doaj.org/article/efb235ba546041178e50b8e0feb382f7