Zobrazeno 1 - 10
of 87
pro vyhledávání: '"N.W.F Kossen"'
Publikováno v:
AIChE Journal. 52:2736-2741
The formation of granules in the spray zone of a top-spray ∞uid-bed granulation process using a known and uniform drop size is studied experimentally and theoretically. Experimental results indicate a multimodal size distribution of spherically-sha
Publikováno v:
Powder Technology, 119(1), 33-44
In this contribution both the development of a multi-particulate delayed release system and a mathematical model to describe its release properties are presented. The formulation consists of a water-soluble core coated with a water-insoluble ethylcel
Publikováno v:
Scopus-Elsevier
AIChE Journal, 45(6), 1202-1210. Wiley
AIChE Journal, 45(6), 1202-1210. Wiley
The novel technique of spraying binder liquid in pulses of short duration on a bubbling fluidized bed was used to study the effect liquid distribution, mixing, and relative humidity has on granule growth. Two important mixing zones in the fluid-bed g
Publikováno v:
Powder Technology, 97(3), 183-190
Wet agglomeration processes have predominantly been investigated by changing operation variables of process-scale experiments. So far, most fundamental work concentrated on the strength of the liquid bonds in the agglomerate and its relation to the p
Publikováno v:
International Journal of Pharmaceutics. 166:89-97
For the predictive modelling of the high-shear pelletisation process it is necessary to have a better understanding of the underlying mechanisms. Therefore, pelletisation experiments were carried out with microcrystalline cellulose and lactose in a c
Publikováno v:
International Journal of Pharmaceutics, 93-102. Elsevier Bedrijfsinformatie b.v.
STARTPAGE=93;ENDPAGE=102;ISSN=0378-5173;TITLE=International Journal of Pharmaceutics
STARTPAGE=93;ENDPAGE=102;ISSN=0378-5173;TITLE=International Journal of Pharmaceutics
Two high-shear mixers, Gral 10 and Gral 25, were used to prepare pellets of microcrystalline cellulose and lactose, using water as binder liquid. Growth of pellets was investigated by measuring the pellet size distribution during the process. On the
Publikováno v:
Journal of Controlled Release, 66(2-3), 293-306. Elsevier Bedrijfsinformatie b.v.
In this contribution both the development of a multi-particulate delayed release system with release properties dependent on the swelling of an UV crosslinked coating and a mathematical model to describe its release properties are presented. The form
Publikováno v:
International Journal of Pharmaceutics, 193(2), 175-187. Elsevier Bedrijfsinformatie b.v.
In the fluid bed agglomeration processes liquid distribution influences the agglomerate growth. We developed a new nozzle that produces uniform droplets, which allows droplets to be easily controlled in size independently of liquid- and airflow of th
Publikováno v:
Chemical Engineering Science. 29:2071-2082
Bubble coalescence phenomena have been examined at Reynolds numbers of 0·5–80 for five different classes of bubbles. The approach velocity of the following bubble ( u 2 ) is experimentally obtained and its behaviour with respect to the leading bub
Publikováno v:
Journal of Agricultural Engineering Research. 16:254-268
By using simple mass and energy balances, the cooling and drying characteristics of a ventilated or barn dried hay stack have been analysed. The results of this approach could be verified with measurements in cylindrical hay stacks (air entrance alon