Zobrazeno 1 - 10
of 42
pro vyhledávání: '"N.V. Owen"'
Publikováno v:
Neurotoxicology and Teratology. 13:283-295
Pergolide was given by oral gavage to mated CD-1 female mice at doses of 0, 1, 20, or 60 mg/kg/day on gestation days (GD) 6-15. Animals assigned to the teratology segment were killed on GD 18 for evaluation of maternal organ weights, and fetal viabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f70818a42a4217e3e73aa5a0ccc5fb3
https://doi.org/10.1016/0892-0362(91)90074-7
https://doi.org/10.1016/0892-0362(91)90074-7
Publikováno v:
Neurotoxicology and Teratology. 13:297-306
Pergolide mesylate is a dopamine agonist and, therefore, reduces prolactin secretion. In Experiment I, pregnant mice were given oral doses of 0, 0.1, 0.3, 1.0 or 3.0 mg/kg/day pergolide on GD 15 through PD 10 or 20 to identify a tolerated dose which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e39aed0618e20ded1b173dafa2189be4
https://doi.org/10.1016/0892-0362(91)90075-8
https://doi.org/10.1016/0892-0362(91)90075-8
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 29(8)
B6C3F1 mice were maintained for 24 months on diets containing 0, 563, 2250 or 4500 ppm trifluralin. These dietary concentrations corresponded to daily doses of approximately 70, 285 or 570 mg/kg body weight, respectively. The control group contained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2f83f13f2ca9cbbad8550806d61228
https://pubmed.ncbi.nlm.nih.gov/1894221
https://pubmed.ncbi.nlm.nih.gov/1894221
Publikováno v:
Journal of Infectious Diseases. 137:S51-S59
The safety of cefamandole nafate in laboratory animals was evaluated in six species. The acute toxicity of cefamandole after intravenous or subcutaneous administration was similar to that of cephalothin sodium. The subacute and chronic toxicity of ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cff2f6cd17d930eb7da03e4015f3bc
https://doi.org/10.1093/infdis/137.supplement.s51
https://doi.org/10.1093/infdis/137.supplement.s51
Publikováno v:
Toxicology and Applied Pharmacology. 86:391-399
Fenarimol (alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-5- pyrimidinemethanol a pyrimidine carbinol fungicide, caused a dose-related decrease in male fertility in Wistar rats. The effect was particularly evident in the anatomically normal progeny of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6d7471f025ee958ad2fb7f0b6e76ac
https://doi.org/10.1016/0041-008x(86)90366-2
https://doi.org/10.1016/0041-008x(86)90366-2
Publikováno v:
Toxicology and Applied Pharmacology. 25:398-409
Tobramycin, an aminoglycoside antibiotic, has been administered to mice, rats, cats and dogs for toxicologic evaluation. The sc LD50 values in mice and rats were 441 and 969 mg/kg, respectively. Deaths were preceded by CNS depression and occurred wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156d20574e320fae822e3f181cb2bca9
https://doi.org/10.1016/0041-008x(73)90313-x
https://doi.org/10.1016/0041-008x(73)90313-x
Publikováno v:
Toxicology and Applied Pharmacology. 18:720-733
Dietary administration of 5-(3,4-dichlorophenyl)-5-ethylbarbituric acid (0.002–0.054% drug diets) to rats for 30 days resulted in centrilobular hypertrophy of hepatocytes and dose-related increases in liver weight, hepatic microsomal protein, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751c2db41b39ad6b21465e74aa7ab17c
https://doi.org/10.1016/s0041-008x(71)80027-3
https://doi.org/10.1016/s0041-008x(71)80027-3
Publikováno v:
Toxicology and Applied Pharmacology. 21:582-585
Daily po administration of the synthetic estrogen trans -4,4′-dimethyl-α,α′-diethylstilbene to bitches for 30 days resulted in papillomatous growths on the serosal surfaces of ovaries and uteri. The morphology resembled that of the naturally oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db0cedf787e25dabc7aec6ce6f7e555
https://doi.org/10.1016/0041-008x(72)90014-2
https://doi.org/10.1016/0041-008x(72)90014-2
Publikováno v:
Toxicology and applied pharmacology. 19(3)
Propoxyphene napsylate was studied in reproduction and teratology experiments in rats and in a teratology experiment in rabbits. Rats were given daily oral doses of 0, 100, 200, or 400 mg/kg, while rabbits were treated with oral doses of 0, 32, or 80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0d9b94623ddab12998c4d74c69e500
https://pubmed.ncbi.nlm.nih.gov/5571351
https://pubmed.ncbi.nlm.nih.gov/5571351
Publikováno v:
Nature. 233:342-343
METHADONE maintenance was reported as a treatment for heroin addiction in 19651, and more than 10,000 patients are now maintained on the drug at more than 100 centres throughout the United States (unpublished Lilly Survey, 1970). Wallach et al.2 obse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498bac5ecfd1c541b3e20a7759bd8e52
https://doi.org/10.1038/233342a0
https://doi.org/10.1038/233342a0