Zobrazeno 1 - 10
of 188
pro vyhledávání: '"N.H. Seemayer"'
Publikováno v:
Toxicology in Vitro. 11:711-715
In our highly industrialized world air pollution has become an important topic. Beside gaseous pollutants airborne particulates are of great medical concern, containing several hundred mostly organic substances. They are incriminated to cause an exce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c4d868661447be680296a3af203377
https://doi.org/10.1016/s0887-2333(97)00065-9
https://doi.org/10.1016/s0887-2333(97)00065-9
Autor:
Kari Hemminki, N.H. Seemayer, Mieczystaw Chorazy, Regina M. Santella, Frederica P. Perera, Grazyna Motykiewicz
Publikováno v:
Toxicology Letters. 88:169-173
New concepts of cancer risk estimation have been developed during the past decade. Short-term bioassays dealing with mutagenicity and carcinogenicity of environmental samples are being replaced by more relevant molecular epidemiology studies. The gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1554a1413ef7ffa3018c62bdeba39620
https://doi.org/10.1016/0378-4274(96)03734-4
https://doi.org/10.1016/0378-4274(96)03734-4
Publikováno v:
Toxicology Letters. 88:55-64
Tracheal epithelial cells of the golden Syrian hamster can be successfully cultivated in vitro and applied as a model system of respiratory tract epithelium. By morphology and growth characteristics of tracheal epithelial cells, "normal cells", "enha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece81c3ab3208249cf7265b184f4bbca
https://doi.org/10.1016/0378-4274(96)03718-6
https://doi.org/10.1016/0378-4274(96)03718-6
Autor:
U. Griwatz, N.H. Seemayer
Publikováno v:
Toxicology in Vitro. 9:403-409
Recent results indicate that tumour necrosis factor alpha (TNFalpha) may have an important role in the pathogenesis of silicosis. Supernatants of macrophages exposed to quartz and coal mine dust were tested for the presence of TNFalpha. Monocytes wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c77c1ef0b273058bf403890410b326f1
https://doi.org/10.1016/0887-2333(95)00026-5
https://doi.org/10.1016/0887-2333(95)00026-5
Autor:
N.H. Seemayer, C. Hornberg
Publikováno v:
Toxicology in Vitro. 9:397-402
The major target site of airborne particulates is the tracheobronchial epithelium of the respiratory tract. It is also the origin of the most common cancer in man, bronchogenic carcinoma. Rodent tracheal epithelial cells in culture can be used to stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7d0f0accbe6852446f53f26acac927
https://doi.org/10.1016/0887-2333(95)00025-4
https://doi.org/10.1016/0887-2333(95)00025-4
Autor:
N.H. Seemayer, Wolfgang Hadnagy
Publikováno v:
Toxicology Letters. 72:23-31
Human monocyte-derived macrophages isolated from peripheral blood were treated with different extracts of airborne particulates collected in the highly industrialized Rhine-Ruhr area. All tested extracts showed a substantial impairment of phagocytosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80aa767dc8f8b8e96b5311448482e28a
https://doi.org/10.1016/0378-4274(94)90006-x
https://doi.org/10.1016/0378-4274(94)90006-x
Publikováno v:
Toxicology in Vitro. 7:365-371
Alveolar macrophages are major target cells for toxicity from inhaled particulates. To investigate pulmonary toxicity induced by airborne particulates a phagocytosis assay using human monocyte-derived macrophage cultures was used. Monocytes were isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd10aff005cabbea77e5afcd4aa0015d
https://doi.org/10.1016/0887-2333(93)90029-5
https://doi.org/10.1016/0887-2333(93)90029-5
Autor:
W. Hadnagy, N.H. Seemayer
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 5(5-6)
The ability of particulate pollutants to act on the mitotic cell division process and to induce aneuploidy in V79 cell cultures has been investigated. Extracts of airborne particulates and particulate car exhaust caused mitotic arrest connected with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bceedddbc91047fecb023237b1e72422
https://pubmed.ncbi.nlm.nih.gov/20732066
https://pubmed.ncbi.nlm.nih.gov/20732066
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 11(5)
A complex chemical mixture of heavy oil (Z1003), composed of polycyclic aromatic hydrocarbons (PAHs) and aza-heterocyclic compounds (AHCs), has been analysed for its ability to induce cell division disturbances on Chinese hamster lung cell line V79.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15536b6cf8c0f0451dafd59097d2e909
https://pubmed.ncbi.nlm.nih.gov/20654374
https://pubmed.ncbi.nlm.nih.gov/20654374
Publikováno v:
Journal of Aerosol Science. 21:387-391
In this study we report the effect of extract of airborne particulates collected in the Rhine-Ruhr region on alveolar macrophages of the rat and on human macrophages in culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52048973ba813a2add7eeeebdaebec38
https://doi.org/10.1016/0021-8502(90)90066-7
https://doi.org/10.1016/0021-8502(90)90066-7