Zobrazeno 1 - 10
of 89
pro vyhledávání: '"N.H. Kulkarni"'
Autor:
N.H. Kulkarni, Ling Yeong Chia, Matthew T. Gillespie, T. J. Martin, Jonathan H. Gooi, Jude E. Onyia, P.W.M. Ho, Nicole C. Walsh, Ivo Kalajzic, J.M.W. Quinn, B. Han, Natalie A. Sims, S. H M McAhren, Morten A. Karsdal, S. Pompolo
Publikováno v:
Bone. 46:1486-1497
The therapeutic goal of increasing bone mass by co-treatment of parathyroid hormone (PTH) and an osteoclast inhibitor has been complicated by the undefined contribution of osteoclasts to the anabolic activity of PTH. To determine whether active osteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0923585224ad02adfa4c4ef1e025950a
https://doi.org/10.1016/j.bone.2010.02.018
https://doi.org/10.1016/j.bone.2010.02.018
Autor:
Pinto, Rochele1 (AUTHOR) rochele.pinto@ktu.edu, Glaskova-Kuzmina, Tatjana1 (AUTHOR) gediminas.monastyreckis@ktu.lt, Zukiene, Kristina2 (AUTHOR) kristina.zukiene@ktu.lt, Monastyreckis, Gediminas1 (AUTHOR) daiva.zeleniakiene@ktu.lt, Novakova, Marie3 (AUTHOR) marie.novakova@synpo.cz, Spacek, Vladimir3 (AUTHOR) vladimir.spacek@synpo.cz, Kovalovs, Andrejs4 (AUTHOR) andrejs.kovalovs@rtu.lv, Aniskevich, Andrey5 (AUTHOR) andrey.aniskevich@pmi.lu.lv, Zeleniakiene, Daiva1 (AUTHOR)
Publikováno v:
Polymers (20734360). Oct2024, Vol. 16 Issue 20, p2909. 15p.
Autor:
Melissa A. Schreiweis, Jude E. Onyia, N.H. Kulkarni, Jon P. Butler, David L. Halladay, Richard E. Higgs, Michael D. Knierman, John E. Hale
Publikováno v:
Journal of Cellular Biochemistry. 101:466-476
The non-mineral component of bone matrix consists of 90% collagenous, 10% non-collagenous proteins. These proteins regulate mineralization, growth, cell signaling and differentiation, and provide bone with its tensile strength. Expression of bone mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9dafc0a271e8d9dae1ece928e2a649b
https://doi.org/10.1002/jcb.21196
https://doi.org/10.1002/jcb.21196
Autor:
Richard E. Higgs, Thomas A. Engler, Henry Uhlman Bryant, Ernst R. Dow, Mathias N'Cho, Bruce D. Gitter, Jude E. Onyia, Jianyong Shou, Trent R. Stewart, David L. Halladay, Tao Wei, T. John Martin, Yanfei L. Ma, Diane L. Sterchi, Amar Kumar, N.H. Kulkarni
Publikováno v:
Journal of Cellular Biochemistry. 102:1504-1518
Parathyroid hormone (PTH) and glycogen synthase kinase-3 (GSK-3) inhibitor 603281-31-8, administered once daily increased bone formation in vivo. We investigated the molecular mechanisms of the anabolic responses of PTH and 603281-31-8 in rat osteope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6dfee062afef2e3f0ef7661e0c47e9
https://doi.org/10.1002/jcb.21374
https://doi.org/10.1002/jcb.21374
Autor:
Keith M. Goldstein, James L. Stevens, Jean-Marie Colet, Shawn T. Estrem, B. L. Ackermann, J. A. Eckstein, Craig E. Thomas, Timothy P. Ryan, N.H. Kulkarni, Leah M. Helvering, B. Liao, Jude E. Onyia, J. Shou, Robert A. Jolly, Tao Wei
Publikováno v:
Biomarkers. 10:153-172
High-throughput molecular-profiling technologies provide rapid, efficient and systematic approaches to search for biomarkers. Supervised learning algorithms are naturally suited to analyse a large amount of data generated using these technologies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd020c11dba99a40a743c981c7e6372
https://doi.org/10.1080/13547500500107430
https://doi.org/10.1080/13547500500107430
Autor:
Henry Uhlman Bryant, M. Zhang, Leah M. Helvering, N.H. Kulkarni, Sutada Lotinun, Charles A. Frolik, Jude E. Onyia, Yanfei L. Ma, Avudaiappan Maran, Rebecca R. Miles, Emily M. Ambrose, Peining Chen, Lawrence M. Gelbert, Tao Wei, Masahiko Sato, Ernst R. Dow, Xi Lin, David L. Halladay, Russell T. Turner, Shuguang Huang
Publikováno v:
Journal of Cellular Biochemistry. 95:403-418
Teriparatide, human PTH (1-34), a new therapy for osteoporosis, elicits markedly different skeletal responses depending on the treatment regimen. In order to understand potential mechanisms for this dichotomy, the present investigation utilized micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c743b61513b4574818eb566546df622b
https://doi.org/10.1002/jcb.20438
https://doi.org/10.1002/jcb.20438
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Autor:
N.H. Kulkarni, P.G. Mitchell, T. Hu, Xi Lin, Leah M. Helvering, Yanfei L. Ma, Anita K. Harvey, R.L. Cain, Tao Wei, Rebecca R. Miles, D.D. Edmondson, J.L. Oskins, Laura V. Hale, T.P. Ryan, Jude E. Onyia, Qingqiang Zeng, Mark Chambers, M.A. Carozza, C. Lin, Frank Lawrence
Publikováno v:
Osteoarthritis and cartilage. 18(7)
Objective The purpose of this study was to use microarray technology to: (1) understand the early molecular events underlying the damage of articular cartilage initiated by this surgical procedure, and (2) determine whether these changes mimic those
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b603d871f1b8bf50d21582c94e50779f
https://pubmed.ncbi.nlm.nih.gov/20434574
https://pubmed.ncbi.nlm.nih.gov/20434574
Autor:
N.H. Kulkarni, Aidas Kriauciunas, Henry Uhlman Bryant, Tao Wei, Min Liu, David L. Halladay, Masahiko Sato, Yanfei L. Ma, Xioayan Tian, T. John Martin, Charles A. Frolik, Thomas A. Engler, Jude E. Onyia, Qingqiang Zeng
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 21(6)
UNLABELLED: GSK-3, a component of the canonical Wnt signaling pathway, is implicated in regulation of bone mass. The effect of a small molecule GSK-3 inhibitor was evaluated in pre-osteoblasts and in osteopenic rats. GSK-3 inhibitor induced osteoblas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a69e73eef9e2ec8a7fe15b5a2ad64a
https://pubmed.ncbi.nlm.nih.gov/16753022
https://pubmed.ncbi.nlm.nih.gov/16753022
Autor:
J. Shou, H.-R. Qian, C. Dotson, W. Tao, L. M. Gelbert, Frank Lawrence, N.H. Kulkarni, Jude E. Onyia, M. N'Cho, C. Lin, C. M. Bull
Publikováno v:
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 10(4)
High-quality biomarkers for disease progression, drug efficacy and toxicity liability are essential for improving the efficiency of drug discovery and development. The identification of drug-activity biomarkers is often limited by access to and the q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5085a0223715685e5e066aa700364a
https://pubmed.ncbi.nlm.nih.gov/16191486
https://pubmed.ncbi.nlm.nih.gov/16191486