Zobrazeno 1 - 10
of 32
pro vyhledávání: '"N.E. Pratt"'
Publikováno v:
Journal of Oral Pathology and Medicine. 10:192-202
Cytoplasmic crystalloids were found in parotid acinar cells of rats given a large (6400 R) single exposure of X-rays to the head and neck. The crystalloids were first observed 1 day after irradiation and became numerous at 3-4 days. They were associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f01c57dae97138545bc5f29627e0ab9
https://doi.org/10.1111/j.1600-0714.1981.tb01265.x
https://doi.org/10.1111/j.1600-0714.1981.tb01265.x
Publikováno v:
Archives of Oral Biology. 22:261-267
X-irradiation exposures of 400, 800, 1600 and 6400 R resulted in dose-related alterations in amylase concentrations and parotid gland weights during the 8 days following irradiation. These effects were not due to irradiation alone but were caused by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836afdec5edf7924ac1d4e181e645a65
https://doi.org/10.1016/0003-9969(77)90111-x
https://doi.org/10.1016/0003-9969(77)90111-x
Publikováno v:
Archives of Oral Biology. 25:781-783
The β-sympathomimetic drug terbutaline was shown to be a powerful secretogogue for the rat parotid gland. It was also found to be capable of causing a transient enlargement of the parotid which was similar to that produced by isoproterenol.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11034941e5e07637efbfbe89ab1a394d
https://doi.org/10.1016/0003-9969(80)90134-x
https://doi.org/10.1016/0003-9969(80)90134-x
Publikováno v:
International journal of radiation oncology, biology, physics. 6(4)
The ultrastructure of rat parotid glands protected by S-2 (3-aminopropylamino) ethyl phosphorothioate (WR-2721) was evaluated 60 days following a single dose of 3.2 kR of X-irradiation and compared with that of similarly irradiated but non-protected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671921a3a31b4be36770305db129a85d
https://pubmed.ncbi.nlm.nih.gov/6248498
https://pubmed.ncbi.nlm.nih.gov/6248498
Publikováno v:
Investigative radiology. 14(2)
A comparison was made of the radioprotective abilities of the chemoradioprotector WR-2721, an amino-thiol, and the beta-sympathomimetic secretogogue isoproterenol on the rat parotid gland. Using the dose-response curve of WR-2721 for gland weights as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd0e84470e17f3d0d3147f75f977c620
https://pubmed.ncbi.nlm.nih.gov/225291
https://pubmed.ncbi.nlm.nih.gov/225291
Publikováno v:
Radiation Research. 58:196
Radiation damage to rat parotid acinar cells was evaluated by electron microscopy using exposures of 400, 800, 1600, and 6400 R. Evidence of intracellular damage was observed at all exposures by the presence of focal cytoplasmic lesions involving all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b04bcc660c44608bf867ce91cd33b379
https://doi.org/10.2307/3573932
https://doi.org/10.2307/3573932
Publikováno v:
Radiation Research. 76:172
WR-2721 protected against the acute phase of radiation damage which is manifest during the first week after irradiation, though recovery occurred both in the presence and absence of such protection. The drug also protected against the chronic phase d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c84d078eb2b31515252ae944f6d94f9
https://doi.org/10.2307/3574936
https://doi.org/10.2307/3574936
Publikováno v:
Radiation Research. 75:317
The radioprotective capacity of the chemoprotector WR-2721 was assessed in the rat parotid gland using gland weight and amylase content as the indicators of effect over the 9-day period following x irradiation with 1.6, 3.2, and 6.4 kR of acute x ray
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::115dafe78a9f12ca14fbd38bced3d6aa
https://doi.org/10.2307/3574907
https://doi.org/10.2307/3574907
Publikováno v:
Radiation Research. 80:348
The radioprotection of the rat parotid gland by WR-2721 alone (DMF, 2.4) was compared to the protection afforded when WR-2721 was given in combination with the hypoxic cell radiosensitizer Ro-07-0582 (DMF, 2.6). It was concluded that the radiosensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c28e3e5ae404001811ccc46ce0d0a9cb
https://doi.org/10.2307/3575063
https://doi.org/10.2307/3575063
Autor:
N.E. Pratt, M. Sodicoff
Publikováno v:
Archives of Oral Biology. 17:1177-IN5
Following X-irradiation with 1600 rad to the head and neck area of rats, parotid glands were examined at 1, 3 and 5 hr, 1, 2, 3, 4, 7 and 8 days for evidence of ultrastructural damage of acinar cells. Damage was evident as early as 3 hours with maxim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6f2bdd25d64b090ca5bf694eae1900
https://doi.org/10.1016/0003-9969(72)90088-x
https://doi.org/10.1016/0003-9969(72)90088-x