Výsledky vyhledávání

Peroxynitrite mediates VEGF's angiogenic signal and functionviaa nitration‐independent mechanism in endothelial cells

Autor: N.-T. Tsai, Manuela Bartoli, M.A. Behzadian, D.H. Platt, Mohamed Al-Shabrawey, Ruth B. Caldwell, N. Ghaly, Kouros Motamed, Azza B. El-Remessy

Publikováno v: The FASEB Journal. 21:2528-2539

The modulation of angiogenic signaling by reactive oxygen species (ROS) is an emerging area of interest in cellular and vascular biology research. We provide evidence here that peroxynitrite, the powerful oxidizing and nitrating free radical, is crit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9d0aa8b4c996531b8ea162cae7efe22
https://doi.org/10.1096/fj.06-7854com

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Neuroprotective and Intraocular Pressure-Lowering Effects of (–)Δ9-Tetrahydrocannabinol in a Rat Model of Glaucoma

Autor: Ruth B. Caldwell, Gregory I. Liou, James Crandall, N.-T. Tsai, Caesar Borlongan, Y. Khalifa, Suraporn Matragoon

Publikováno v: Ophthalmic Research. 39:69-75

In glaucoma, retinal ganglion cell (RGC) death is induced by many risk factors, including ocular hypertension. It has been proposed that glutamate-mediated oxidative stress may also contribute to this RGC death. Cannabinoids are known to possess ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c216557f8fd9109e015498152bf7ed57
https://doi.org/10.1159/000099240

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Neuroprotective and Blood-Retinal Barrier-Preserving Effects of Cannabidiol in Experimental Diabetes

Autor: N.-T. Tsai, Y. Khalifa, Ruth B. Caldwell, Mohamed Al-Shabrawey, Gregory I. Liou, Azza B. El-Remessy

Publikováno v: The American Journal of Pathology. 168:235-244

Diabetic retinopathy is characterized by blood-retinal barrier (BRB) breakdown and neurotoxicity. These pathologies have been associated with oxidative stress and proinflammatory cytokines, which may operate by activating their downstream target p38

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665b0b05de17110c70fd245e43abc7cb
https://doi.org/10.2353/ajpath.2006.050500

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VEGF‐induced paracellular permeability in cultured endothelial cells involves urokinase and its receptor

Autor: N.-T. Tsai, Ruth B. Caldwell, Gregory I. Liou, Nagla Ghaly, M. Ali Behzadian, L. Jack Windsor

Publikováno v: The FASEB Journal. 17:752-754

Vascular endothelial growth factor/vascular permeability factor (VEGF) has been implicated in blood/tissue barrier dysfunctions associated with pathological angiogenesis, but the mechanisms of VEGF-induced permeability increase are poorly understood.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d925b8d0da5e28d186fa266288b35238
https://doi.org/10.1096/fj.02-0484fje

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DiI labeling and homeobox gene islet-1 expression reveal the contribution of ventral neural tube cells to the formation of the avian trigeminal ganglion

Autor: G S, Sohal, D E, Bockman, M M, Ali, N T, Tsai

Publikováno v: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 14(4)

Cells of the neural tube are thought to be committed to form only the central nervous system, whereas the peripheral nervous system is believed to be derived from neural crest cells and from placodes, which are specialized regions of the surface ecto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::12c84a38cb287930bbc92c2113c8f3f1
https://pubmed.ncbi.nlm.nih.gov/8884375

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Akademický článek

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Role of IL-6 in Angiotensin II–Induced Retinal Vascular Inflammation

Autor: Maritza J. Romero, Wenbo Zhang, Doan T. Nguyen, Robert W. Caldwell, Ruth B. Caldwell, Michael W. Brands, Modesto Rojas, Mohamed Al-Shabrawey, Dexter L. Lee, N.-T. Tsai, Gregory I. Liou

Publikováno v: Investigative Opthalmology & Visual Science. 51:1709

Retinal vascular inflammation is a common feature of blinding diseases such as diabetic retinopathy, retinopathy of prematurity (ROP), and choroidal neovascularization.1 Interleukin (IL)-6 is a potent proinflammatory cytokine involved in many patholo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf08514a86ebdeb0cd513838647d083
https://doi.org/10.1167/iovs.09-3375

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NAD(P)H Oxidase-Dependent Regulation of CCL2 Production during Retinal Inflammation

Autor: Gregory I. Liou, Modesto Rojas, Ruth B. Caldwell, Robert W. Caldwell, Brenda Lilly, N.-T. Tsai, Wenbo Zhang, Tahira Lemtalsi

Publikováno v: Investigative Opthalmology & Visual Science. 50:3033

Vascular inflammation is believed to play a critical role in the pathogenesis of a variety of retinal diseases, such as diabetic retinopathy, uveitis, and ischemic retinopathy. A common feature associated with these diseases is increased leukocyte ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061b9020e85aac151b48a854181ec5ea
https://doi.org/10.1167/iovs.08-2676

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Akademický článek

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Delay-Bond Graph Models for Geared Torsional Systems

Autor: S. M. Wang, N. T. Tsai

Publikováno v: Journal of Applied Mechanics. 41:366-370

The dynamic responses of geared torsional systems are analyzed with the delay-bond graph technique. By transforming the power variables into torsional wave variables, the torsional elements are modeled as transmission line elements. The nonlinear ele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a19b1d4b379a50717f4adc5e3bd495c
https://doi.org/10.1115/1.3423295

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