Zobrazeno 1 - 10 of 269 pro vyhledávání: '"N. von Ahsen"'
1
Longitudinal analyses of anti-JCV antibody index for risk assessment of progressive multifocal leukoencephalopathy
Autor: Meena Subramanyam, Anke Salmen, N. von Ahsen, Tatiana Plavina, Robert Hoepner, Anne-Kathrin Trampe, Geoffrey Kuesters, R. Gold, Andrew T. Chan
Publikováno v: Salmen, Anke; von Ahsen, N.; Trampe, A. K.; Hoepner, R.; Plavina, T.; Subramanyam, M.; Kuesters, G.; Gold, R.; Chan, Andrew (2016). Longitudinal analyses of anti-JCV antibody index for risk assessment of progressive multifocal leukoencephalopathy. Multiple sclerosis journal-experimental, translational and clinical, 2, p. 205521731663000. Sage Publications 10.1177/2055217316630008
Multiple sclerosis journal-experimental, translational and clinical
Risk assessment for natalizumab-associated progressive multifocal leukoencephalopathy (Nat-PML) comprises the anti-JC virus (JCV) antibody index (AI). The anti-JCV AI was longitudinally determined in a natalizumab-treated MS cohort (Nat-MS, n = 468)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26dedeae282ff90384b93979c380c266
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2
Inosine monophosphate dehydrogenase activity in paediatrics: age-related regulation and response to mycophenolic acid
Autor: A. Rother, L. T. Weber, Petra Glander, David Czock, Reinhard Feneberg, N. von Ahsen, Klemens Budde, Victor W. Armstrong, Michael Oellerich, E. Vitt, Burkhard Tönshoff
Publikováno v: European Journal of Clinical Pharmacology. 68:913-922
Since many drug targets and metabolizing enzymes are developmentally regulated, we investigated a potential comparable regulation of inosine 5’-monophosphate dehydrogenase (IMPDH) activity that has recently been advocated as a pharmacodynamic bioma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c385bbbe6d027cf91c0f6038c71e2ac2
https://doi.org/10.1007/s00228-011-1203-4
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3
ATP-Binding Cassette Transporters in Inflammatory Brain Disease
Autor: N. von Ahsen, Andrew T. Chan, R. Gold
Publikováno v: Current Pharmaceutical Design. 17:2803-2807
Owing to therapeutic progress, the role of ABC-transporters in infectious and autoimmune inflammatory CNS-diseases has recently gained considerable attention. In HIV-encephalitis and HIV-associated neurocognitive disorders, ABC-transporters are discu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2eebda9ff5ef165fe60b0097cc295f
https://doi.org/10.2174/138161211797440131
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4
Thrombophilia in patients with chronic venous leg ulcers-a study on patients with or without post-thrombotic syndrome
Autor: N. von Ahsen, Markus Zutt, Michael P. Schön, Christine Neumann, Ullrich Krüger, Albert Rosenberger, Lutz Kretschmer
Publikováno v: Journal of the European Academy of Dermatology and Venereology. 25:1432-1439
Background Chronic venous leg ulcers (CVU) cause considerable burden of disease for the patients as well as enormous costs for health care systems. The pathophysiology of CVU is complex and not entirely understood. So far reliable pathogenic and/or p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20f64f043c92df115d1669ff1f5e8f5d
https://doi.org/10.1111/j.1468-3083.2011.04001.x
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5
ABC-transporter gene-polymorphisms are potential pharmacogenetic markers for mitoxantrone response in multiple sclerosis
Autor: N. König, Frauke Zipp, Alexander Winkelmann, Andrew T. Chan, H. Pannek, J. Dörr, Uwe K. Zettl, S. Cotte, N. von Ahsen, B. Huber, Ralf Gold, Friedemann Paul, Neus Téllez, Xavier Montalban, Niels Kruse, H. Koepsell, Fred Lühder, M Starck
Publikováno v: Brain. 132:2517-2530
Escalation therapy with mitoxantrone (MX) in highly active multiple sclerosis is limited by partially dose-dependent side-effects. Predictors of therapeutic response may result in individualized risk stratification and MX dosing. ATP-binding cassette
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ef52a5e48d3d9943ca0a73ff132599
https://doi.org/10.1093/brain/awp164
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6
Apolipoprotein E polymorphism, homocysteine serum levels and hippocampal volume in patients with alcoholism: an investigation of a gene–environment interaction
Autor: Julia Wilhelm, Thomas Hillemacher, Johannes Kornhuber, Stefan Bleich, N. von Ahsen, Helge Frieling
Publikováno v: The Pharmacogenomics Journal. 8:117-121
There is growing evidence that disadvantageous influences of the apolipoprotein E4 allele in the central nervous system are modified by environmental and dietary conditions. The present study investigated the gene-environment interaction of apolipopr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3093b2ee9214de58d59ab3e096c2da4
https://doi.org/10.1038/sj.tpj.6500453
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7
Homocysteine levels in aqueous humor and plasma of patients with primary open-angle glaucoma
Autor: Johannes B. Roedl, Gottfried O. H. Naumann, Anselm Jünemann, Friedrich E. Kruse, Udo Reulbach, Ursula Schlötzer-Schrehardt, Stefan Bleich, Robert Rejdak, N. von Ahsen, Johannes Kornhuber
Publikováno v: Journal of Neural Transmission. 114:445-450
We determined homocysteine (Hcy) levels in aqueous humor (AH) and plasma and their association with B-vitamin levels in patients with primary open-angle glaucoma (POAG) and controls. Both AH Hcy and plasma Hcy levels were significantly increased in P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c25da376e3d30d2d910a74ddfe19146
https://doi.org/10.1007/s00702-006-0556-9
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9
MDR1 Haplotypes Modify BEN Disease Risk: A Study in Bulgarian Patients with Balkan Endemic Nephropathy Compared to Healthy Controls
Autor: Tzvetan Dimitrov, Victor W. Armstrong, Michael Oellerich, Draga Toncheva, N. von Ahsen, S. Atanasova
Publikováno v: Nephron Experimental Nephrology. 96:e7-e13
Background: Balkan endemic nephropathy (BEN) is a slow progressive nephropathy with frequent occurrence of uroepithelial tumors in the upper urinary tract. Genetic factors involved in xenobiotic detoxification mechanisms may cause genetic predisposit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c188d9f938f716d202761392b131725a
https://doi.org/10.1159/000075571
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10
CPAP-therapy effectively lowers serum homocysteine in obstructive sleep apnea syndrome
Autor: Stefan Bleich, C. Berger, Paul Dieter Niedmann, Johannes Kornhuber, Geert Mayer, Wolfgang Jordan, E. Rüther, N. von Ahsen, Stefan Cohrs, Andrea Rodenbeck
Publikováno v: Journal of Neural Transmission. 111:683-689
Assessment of serum total homocysteine (tHcy) in patients with obstructive sleep apnea (OSA) syndrome is highly relevant since both are strongly associated with stroke and cognitive dysfunction. Seven of 16 untreated OSA patients showed tHcy levels e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffe118db7c4bcb87b4fb60ef4755924
https://doi.org/10.1007/s00702-004-0130-2
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