Zobrazeno 1 - 10
of 71
pro vyhledávání: '"N. van den Brink"'
Autor:
Patrick J. Engelberts, Ida H. Hiemstra, Bart de Jong, Danita H. Schuurhuis, Joyce Meesters, Irati Beltran Hernandez, Simone C. Oostindie, Joost Neijssen, Edward N. van den Brink, G. Jean Horbach, Sandra Verploegen, Aran F. Labrijn, Theodora Salcedo, Janine Schuurman, Paul W.H.I Parren, Esther C.W. Breij
Publikováno v:
EBioMedicine, Vol 52, Iss , Pp - (2020)
Background: DuoBody®-CD3xCD20 (GEN3013) is a full-length human IgG1 bispecific antibody (bsAb) recognizing CD3 and CD20, generated by controlled Fab-arm exchange. Its Fc domain was silenced by introduction of mutations L234F L235E D265A. Methods: T-
Externí odkaz:
https://doaj.org/article/8eed60dbcc62461eb9d7224a1bb469dc
Autor:
Ignacio Melero, Maria Jure-Kunkel, Uğur Şahin, Tahamtan Ahmadi, Ulf Forssmann, Özlem Türeci, Kate Sasser, Eleni Lagkadinou, Gaurav Bajaj, Esther C.W. Breij, Sebastian Kreiter, David Satijn, Mustafa Diken, Mark Fereshteh, Edward N. van den Brink, Aras Toker, Theo S. Plantinga, Juliane Quinkhardt, Angelica Sette, Fulvia Vascotto, Dennis Verzijl, Eliana Stanganello, Saskia M. Burm, Theodora W. Salcedo, Bianca Sänger, Jordan M. Blum, Kristina B. Schoedel, Maria E. Rodriguez-Ruiz, Guzman Alonso, Patricia M. LoRusso, Emiliano Calvo, Corinne Maurice-Dror, Eytan Ben-Ami, Ravit Geva, Friederike Gieseke, Isil Altintas, Elena Garralda, Alexander Muik
Checkpoint inhibitors (CPI) have revolutionized the treatment paradigm for advanced solid tumors; however, there remains an opportunity to improve response rates and outcomes. In preclinical models, 4-1BB costimulation synergizes with CPIs targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77571654a67b8230111048825587e8ec
https://doi.org/10.1158/2159-8290.c.6549569
https://doi.org/10.1158/2159-8290.c.6549569
Autor:
Ignacio Melero, Maria Jure-Kunkel, Uğur Şahin, Tahamtan Ahmadi, Ulf Forssmann, Özlem Türeci, Kate Sasser, Eleni Lagkadinou, Gaurav Bajaj, Esther C.W. Breij, Sebastian Kreiter, David Satijn, Mustafa Diken, Mark Fereshteh, Edward N. van den Brink, Aras Toker, Theo S. Plantinga, Juliane Quinkhardt, Angelica Sette, Fulvia Vascotto, Dennis Verzijl, Eliana Stanganello, Saskia M. Burm, Theodora W. Salcedo, Bianca Sänger, Jordan M. Blum, Kristina B. Schoedel, Maria E. Rodriguez-Ruiz, Guzman Alonso, Patricia M. LoRusso, Emiliano Calvo, Corinne Maurice-Dror, Eytan Ben-Ami, Ravit Geva, Friederike Gieseke, Isil Altintas, Elena Garralda, Alexander Muik
Supplementary Figure from Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e568b16421048c1e79b8dfceca7e687
https://doi.org/10.1158/2159-8290.22541198.v1
https://doi.org/10.1158/2159-8290.22541198.v1
Autor:
P. Movalli, K. Biesmeijer, G. Gkotsis, N. Alygizakis, M.C. Nika, K. Vasilatos, M. Kostakis, N.S. Thomaidis, P. Oswald, M. Oswaldova, J. Slobodnik, N. Glowacka, J.C.E.W. Hooijmeijer, R.A. Howison, R.W.R.J. Dekker, N. van den Brink, T. Piersma
Publikováno v:
Chemosphere, 321
Chemosphere, 321:138145. PERGAMON-ELSEVIER SCIENCE LTD
Chemosphere 321 (2023)
Chemosphere, 321:138145. PERGAMON-ELSEVIER SCIENCE LTD
Chemosphere 321 (2023)
The Dutch breeding population of the black-tailed godwit Limosa limosa limosa has declined substantially over recent decades; the role of contaminants is unknown. We analysed liver samples from 11 adult birds found dead on their breeding grounds in S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc45c5612dfcab6e3aec8b606cfc394
https://www.vliz.be/imisdocs/publications/90/387290.pdf
https://www.vliz.be/imisdocs/publications/90/387290.pdf
Autor:
N. van den Brink, L. Meesters, F. Pardow, M.G. Brewer, S. Roelofs, B. Homey, E. van den Bogaard, J.P. Smits
Publikováno v:
Journal of Investigative Dermatology. 143:S122
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5406cde719a0de3103def32fca70f753
https://doi.org/10.1016/j.jid.2023.03.719
https://doi.org/10.1016/j.jid.2023.03.719
Publikováno v:
Journal of Investigative Dermatology. 142:S213
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eff5bf48c2f36ed5e241fd4e4496cbf0
https://doi.org/10.1016/j.jid.2022.09.205
https://doi.org/10.1016/j.jid.2022.09.205
Autor:
H. Niehues, G. Rikken, F. Kersten, J. Eeftens, M. Oortveld, null D van der krieken, P. Jansen, I.M. van Vlijmen-Willems, J.P. Smits, N. van den Brink, W. Hendriks, T. Ederveen, J. Schalkwijk, P.L. Zeeuwen, E.H. van den Bogaard
Publikováno v:
Journal of Investigative Dermatology. 142:S210
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be1c37454b42680b2b69e2beb642beae
https://doi.org/10.1016/j.jid.2022.09.183
https://doi.org/10.1016/j.jid.2022.09.183
Autor:
Alexander Muik, Elena Garralda, Isil Altintas, Friederike Gieseke, Ravit Geva, Eytan Ben-Ami, Corinne Maurice-Dror, Emiliano Calvo, Patricia M. LoRusso, Guzman Alonso, Maria E. Rodriguez-Ruiz, Kristina B. Schoedel, Jordan M. Blum, Bianca Sänger, Theodora W. Salcedo, Saskia M. Burm, Eliana Stanganello, Dennis Verzijl, Fulvia Vascotto, Angelica Sette, Juliane Quinkhardt, Theo S. Plantinga, Aras Toker, Edward N. van den Brink, Mark Fereshteh, Mustafa Diken, David Satijn, Sebastian Kreiter, Esther C.W. Breij, Gaurav Bajaj, Eleni Lagkadinou, Kate Sasser, Özlem Türeci, Ulf Forssmann, Tahamtan Ahmadi, Uğur Şahin, Maria Jure-Kunkel, Ignacio Melero
Publikováno v:
Scientia
Checkpoint inhibitors (CPI) have revolutionized the treatment paradigm for advanced solid tumors; however, there remains an opportunity to improve response rates and outcomes. In preclinical models, 4-1BB costimulation synergizes with CPIs targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f076437eb0766ba05d68e27c29cadd1
https://pubmed.ncbi.nlm.nih.gov/35491648
https://pubmed.ncbi.nlm.nih.gov/35491648
Publikováno v:
Journal of Investigative Dermatology. 141:S172
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ac7de4a7a3b5ed5e5e2961eb3e788da
https://doi.org/10.1016/j.jid.2021.08.142
https://doi.org/10.1016/j.jid.2021.08.142