Zobrazeno 1 - 10
of 103
pro vyhledávání: '"N. van Vlies"'
Autor:
H. Hassani Lahsinoui, F. Amraoui, L. J. A. Spijkers, G. J. M. Veenboer, S. L. M. Peters, N. van Vlies, L. Vogt, C. Ris-Stalpers, B. J. H. van den Born, G. B. Afink
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Preeclampsia, an important cause of maternal and fetal morbidity and mortality, is associated with increased sFLT1 levels and with structural and functional damage to the glycocalyx contributing to endothelial dysfunction. We investigated gl
Externí odkaz:
https://doaj.org/article/d29d07250c854ff189694cdfc477c593
Autor:
J. Gloerich, D.M. van den Brink, J. P.N. Ruiter, N. van Vlies, F.M. Vaz, R. J.A. Wanders, S. Ferdinandusse
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 1, Pp 77-85 (2007)
Phytol, a branched-chain fatty alcohol, is the naturally occurring precursor of phytanic and pristanic acid, branched-chain fatty acids that are both ligands for the nuclear hormone receptor peroxisome proliferator-activated receptor α (PPARα). To
Externí odkaz:
https://doaj.org/article/b815119721f64338b249701cc076ea95
Autor:
J. Gloerich, N. van Vlies, G.A. Jansen, S. Denis, J.P.N. Ruiter, M.A. van Werkhoven, M. Duran, F.M. Vaz, R.J.A. Wanders, S. Ferdinandusse
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 4, Pp 716-726 (2005)
Branched-chain fatty acids (such as phytanic and pristanic acid) are ligands for the nuclear hormone receptor peroxisome proliferator-activated receptor α (PPARα) in vitro. To investigate the effects of these physiological compounds in vivo, wild-t
Externí odkaz:
https://doaj.org/article/c2125a5374d441dea955f933fc3461f0
Autor:
Liffert Vogt, Carrie Ris-Stalpers, G. J. M. Veenboer, Stephan L. M. Peters, Fouad Amraoui, Gijs B. Afink, B.J.H. van den Born, H. Hassani Lahsinoui, N. van Vlies, Léon J. A. Spijkers
Publikováno v:
Scientific reports, 11(1):4387. Nature Publishing Group
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Preeclampsia, an important cause of maternal and fetal morbidity and mortality, is associated with increased sFLT1 levels and with structural and functional damage to the glycocalyx contributing to endothelial dysfunction. We investigated glycocalyx
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dee20188384cd8588c720b47334fcd2
https://pure.amc.nl/en/publications/soluble-syndecan1-and-glycosaminoglycans-in-preeclamptic-and-normotensive-pregnancies(d0591adb-ef6f-4a97-9d6e-35b9bdd94078).html
https://pure.amc.nl/en/publications/soluble-syndecan1-and-glycosaminoglycans-in-preeclamptic-and-normotensive-pregnancies(d0591adb-ef6f-4a97-9d6e-35b9bdd94078).html
Akademický článek
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Autor:
Tom Wagemans, Lies H. Hoefsloot, Lindsey Welling, Frits A. Wijburg, A. T. van der Ploeg, Olga L. Meijer, N. van Vlies, George J G Ruijter, Hennie T. Brüggenwirth, Marlies J. Valstar
Publikováno v:
Journal of inherited metabolic disease, 39(3), 437-445. Springer Netherlands
Journal of Inherited Metabolic Disease
Journal of Inherited Metabolic Disease, 39(3), 437-445. Springer Netherlands
Journal of Inherited Metabolic Disease
Journal of Inherited Metabolic Disease, 39(3), 437-445. Springer Netherlands
Background Mucopolysaccharidosis type IIIB (MPS IIIB) is a rare genetic disorder in which the deficiency of the lysosomal enzyme N-acetyl-α-glucosaminidase (NAGLU) results in the accumulation of heparan sulfate (HS), leading to progressive neurocogn
Publikováno v:
JIMD Reports ISBN: 9783662575765
JIMD reports, 39, 97-106. Springer Berlin
JIMD reports, 39, 97-106. Springer Berlin
In the severe neurodegenerative disorder mucopolysaccharidosis type IIIB (MPSIIIB or Sanfilippo disease type B), deficiency of the lysosomal enzyme N-acetyl-α-glucosaminidase (NAGLU) results in accumulation of heparan sulfate. Patients present with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb3a1b0b2a1f926751f53808822fff9
https://europepmc.org/articles/PMC5953891/
https://europepmc.org/articles/PMC5953891/
Publikováno v:
Molecular genetics and metabolism, 122(1-2), 100-106. Academic Press Inc.
Background: The autosomal recessive, neurodegenerative disorder mucopolysaccharidosis type IIIB (MPSIIIB) is caused by a deficiency of the lysosomal enzyme N-acetyl-alpha-glucosaminidase (NAGLU), resulting in accumulation of heparan sulfate. The dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5140b4cb4005aa513dcb84b8478f7f6
https://pure.amc.nl/en/publications/processing-of-mutant-nacetylalphaglucosaminidase-in-mucopolysaccharidosis-type-iiib-fibroblasts-cultured-at-low-temperature(8a071ea5-0856-433a-bc90-590dbb0e385e).html
https://pure.amc.nl/en/publications/processing-of-mutant-nacetylalphaglucosaminidase-in-mucopolysaccharidosis-type-iiib-fibroblasts-cultured-at-low-temperature(8a071ea5-0856-433a-bc90-590dbb0e385e).html
Autor:
Wim Kulik, H. van Lenthe, Lodewijk IJlst, Tom Wagemans, J. de Ruijter, N. van Vlies, F. A. Wijburg
Publikováno v:
Journal of inherited metabolic disease, 36(2), 271-279. Springer Netherlands
Sanfilippo disease (Mucopolysaccharidosis III) is a neurodegenerative lysosomal disorder characterized by accumulation of the glycosaminoglycan heparan sulfate (HS). MPS III has a large phenotypic variability and early assessment of disease severity
Autor:
E.M. van der Beek, Astrid Hogenkamp, N. van Vlies, Annemarie Oosting, Johan Garssen, Alison L. Fear, Philip C. Calder, B.J.M. van de Heijning, B.C.A.M. van Esch
Publikováno v:
Journal of Developmental Origins of Health and Disease. 2:112-123
Linoleic acid and α-linolenic acid are essential fatty acids (eFAs) and have to be acquired from the diet. eFAs are the precursors for long-chain polyunsaturated fatty acids (lcPUFAs), which are important immune-modulating compounds. lcPUFAs can be