Zobrazeno 1 - 10
of 10
pro vyhledávání: '"N. Yu. Golik"'
Publikováno v:
Chemistry of Heterocyclic Compounds. 49:1323-1330
The ethyl ester of 7-hydroxy-5-oxo-2,3-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-6-carboxylic acid reaction with bromine in anhydrous acetic acid producing a mixture of the 9-bromo-substituted product and 6-ethoxycarbonyl-5,7-dihydroxy-2,3-dihydro-1H-p
Publikováno v:
Journal of Organic and Pharmaceutical Chemistry. 11:32-35
Publikováno v:
Chemistry of Heterocyclic Compounds. 48:1665-1669
Treatment of ethyl 7-hydroxy-5-oxo-2,3-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-6-carboxylate with bromine in aqueous acetic acid solution gave not only the expected ethyl 2-bromo-1,3-dioxo-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxyl
Publikováno v:
Chemistry of Heterocyclic Compounds. 47:1122-1127
Hydroxy- and alkoxyanilides of 6-hydroxy-2-methyl-4-oxo-2,4-dihydro-1H-pyrrolo[3,2,1-ij]quinoline-5-carboxylic acids have been synthesized as potential diuretic agents. Features of their purification, their steric structure, and biological activity a
Publikováno v:
Chemistry of Heterocyclic Compounds. 47:826-832
A targeted synthesis of a series of halo-substituted 6-hydroxy-2-methyl-4-oxo-1,2-dihydro-4H-pyrrolo-[3,2,1-ij]quinoline-5-carboxylic acid anilides have been carried out. Peculiarites of the 1H NMR spectra and the results of investigating the diureti
Publikováno v:
Chemistry of Heterocyclic Compounds. 47:833-837
A novel method has been developed for the synthesis of 4-hydroxy-2-oxo-1,2-dihydroquinoline3-carboxylic acids esters based on the use of monoethyl malonate as an acylating agent in the presence of N,N'-dicyclohexylcarbodiimide and characterized by hi
Publikováno v:
Chemistry of Heterocyclic Compounds. 46:1459-1466
Modified methods are proposed for the preparation of the ethyl ester and alkylamides of 1-hydroxy-3-oxo-6,7-dihydro-3H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid. A comparative analysis has been carried out of the steric structure and diuretic ac
Publikováno v:
ChemInform. 43
Publikováno v:
ChemInform. 43
A novel access to quinoline-3-carboxylic esters using DCC is studied and possible side reactions between the acylating agent (II) and DCC are discussed.
Publikováno v:
ChemInform. 42
Title compounds (V) (17 examples) are prepared starting from tetrahydroquinoline (I) by modified methods.