Zobrazeno 1 - 10
of 192
pro vyhledávání: '"N. Winston"'
Autor:
Stephanie S. Sloley, Bevan S. Main, Charisse N. Winston, Alex C. Harvey, Alice Kaganovich, Holly T. Korthas, Adam P. Caccavano, David N. Zapple, Jian-young Wu, John G. Partridge, Mark R. Cookson, Stefano Vicini, Mark P. Burns
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Repeated head impact exposure can cause memory and behavioural impairments but the physiological changes in the brain are not well understood. Here, the authors reveal synaptic adaptations as a potential mechanism for early abnormal behavioural event
Externí odkaz:
https://doaj.org/article/8e3cddd729eb493188315a1ff611d883
Autor:
Melonie N. Vaughn, Charisse N. Winston, Natalie Levin, Robert A. Rissman, Victoria B. Risbrough
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
Mild traumatic brain injuries (mTBI) are common injuries across civilian and military populations. Although most individuals recover after mTBI, some individuals continue to show long-term symptoms as well as increased risk for neurodegenerative and
Externí odkaz:
https://doaj.org/article/3027bc66fe5b4c1188bcfdf36c7075c5
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 61-66 (2019)
Abstract Introduction Levels of complement proteins (CPs) in plasma astrocyte‐derived exosomes (ADEs) that are abnormal in Alzheimer's disease (AD) have not been assessed in mild cognitive impairment (MCI). Methods Participants (n = 20 per group) h
Externí odkaz:
https://doaj.org/article/f4487646af6b4c2e880ba353df3a3c57
Publikováno v:
Neural Comput
Individual neurons in the brain have complex intrinsic dynamics that are highly diverse. We hypothesize that the complex dynamics produced by networks of complex and heterogeneous neurons may contribute to the brain’s ability to process and respond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b661fbc7176a0aa97dde52108c36cb
https://doi.org/10.1162/neco_a_01571
https://doi.org/10.1162/neco_a_01571
Autor:
Charisse N. Winston, Oliver Langford, Natalie Levin, Rema Raman, Kevin Yarasheski, Tim West, Sara Abdel-Latif, Michael Donohue, Akinori Nakamura, Kenji Toba, Colin L. Masters, James Doecke, Reisa A. Sperling, Paul S. Aisen, Robert A. Rissman
Publikováno v:
Journal of Alzheimer's Disease. 92:95-107
Background: Participant eligibility for the A4 Study was determined by amyloid PET imaging. Given the disadvantages of amyloid PET imaging in accessibility and cost, blood-based biomarkers may serve as a sufficient biomarker and more cost-effective s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fd59f85aa61ed23fc962a76be568c9b
https://doi.org/10.3233/jad-221118
https://doi.org/10.3233/jad-221118
Autor:
X Anton, Alvarez, Charisse N, Winston, James W, Barlow, Floyd M, Sarsoza, Irene, Alvarez, Manuel, Aleixandre, Carlos, Linares, Manuel, García-Fantini, Birgit, Kastberger, Stefan, Winter, Robert A, Rissman
Publikováno v:
Journal of Alzheimer's Disease. 90:705-717
Background: Plasma neuronal-derived extracellular vesicles (NDEV) contain proteins of pathological, diagnostic, and therapeutic relevance. Objective: We investigated the associations of six plasma NDEV markers with Alzheimer's disease (AD) severity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07af4caadd5e8b1f1cdd9824187dc3b9
https://doi.org/10.3233/jad-220575
https://doi.org/10.3233/jad-220575
Autor:
Patrick Reilly, Charisse N. Winston, Kelsey R. Baron, Margarita Trejo, Edward M. Rockenstein, Johnny C. Akers, Najla Kfoury, Marc Diamond, Eliezer Masliah, Robert A. Rissman, Shauna H. Yuan
Publikováno v:
Neurobiology of Disease, Vol 106, Iss , Pp 222-234 (2017)
Tauopathies are a class of neurodegenerative diseases, including Alzheimer's disease, frontotemporal dementia and progressive supranuclear palsy, which are associated with the pathological aggregation of tau protein into neurofibrillary tangles (NFT)
Externí odkaz:
https://doaj.org/article/6a8083b02931438ba22fb5252d2c5236
Autor:
Charisse N. Winston, Haylie K. Romero, Maya Ellisman, Sophie Nauss, David A. Julovich, Tori Conger, James R. Hall, Wendy Campana, Sid E. O’Bryant, Caroline M. Nievergelt, Dewleen G. Baker, Victoria B. Risbrough, Robert A. Rissman
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Mild traumatic brain injury (mTBI) disproportionately affects military service members and is very difficult to diagnose. To-date, there is currently no blood-based, diagnostic biomarker for mTBI cases with persistent post concussive symptoms. To exa
Externí odkaz:
https://doaj.org/article/b7d761da37a541618003c1eff7ef0ea5
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Autor:
Charisse N. Winston, Edward J. Goetzl, Johnny C. Akers, Bob S. Carter, Edward M. Rockenstein, Douglas Galasko, Eliezer Masliah, Robert A. Rissman
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 3, Iss 1, Pp 63-72 (2016)
Abstract Introduction Levels of Alzheimer's disease (AD)‐related proteins in plasma neuronal derived exosomes (NDEs) were quantified to identify biomarkers for prediction and staging of mild cognitive impairment (MCI) and AD. Methods Plasma exosome
Externí odkaz:
https://doaj.org/article/afe832bdcf33436f9dc64d3e0d96516c