Zobrazeno 1 - 10
of 257
pro vyhledávání: '"N. Wein"'
Autor:
Sara Moradi Tuchayi, Yeva Khachatryan, Ying Wang, R. Rox Anderson, Jialiang S. Wang, Marc N. Wein, Lilit Garibyan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Reduction in visceral adipose tissue (VAT) mass reduces body weight and metabolic disease risk in obese patients. However surgical removal of VAT is highly invasive and thus not clinically feasible. We developed an injectable ice slurry for
Externí odkaz:
https://doaj.org/article/b84a7cd2d8714ff4bbcf30f2d2f2379d
Autor:
Sung-Hee Yoon, Mark B. Meyer, Carlos Arevalo, Murat Tekguc, Chengcheng Zhang, Jialiang S. Wang, Christian D. Castro Andrade, Katelyn Strauss, Tadatoshi Sato, Nancy A. Benkusky, Seong Min Lee, Rebecca Berdeaux, Marc Foretz, Thomas B. Sundberg, Ramnik J. Xavier, Charles H. Adelmann, Daniel J. Brooks, Anthony Anselmo, Ruslan I. Sadreyev, Ivy A. Rosales, David E. Fisher, Navin Gupta, Ryuji Morizane, Anna Greka, J. Wesley Pike, Michael Mannstadt, Marc N. Wein
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
The renal actions of parathyroid hormone (PTH) promote 1,25-vitamin D generation; however, the signaling mechanisms that control PTH-dependent vitamin D activation remain unknown. Here, we demonstrated that salt-inducible kinases (SIKs) orchestrated
Externí odkaz:
https://doaj.org/article/807eb29db7bc4680b7215fddd31857a3
Autor:
Wen Zhou, Petra Simic, Iris Y. Zhou, Peter Caravan, Xavier Vela Parada, Donghai Wen, Onica L. Washington, Maria Shvedova, Kerry A. Pierce, Clary B. Clish, Michael Mannstadt, Tatsuya Kobayashi, Marc N. Wein, Harald Jüppner, Eugene P. Rhee
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 8 (2023)
How phosphate levels are detected in mammals is unknown. The bone-derived hormone fibroblast growth factor 23 (FGF23) lowers blood phosphate levels by reducing kidney phosphate reabsorption and 1,25(OH)2D production, but phosphate does not directly s
Externí odkaz:
https://doaj.org/article/e89541dfb86a4e3cba30439d498ee8eb
Autor:
Josephine H. Li, Lauren E. Hanley, Camille E. Powe, Jacqueline A. Seiglie, Melanie S. Haines, Marc N. Wein, Amy Bregar, Karen K. Miller, Laura E. Dichtel
Publikováno v:
Journal of Clinical and Translational Science, Vol 7 (2023)
Physician parents encounter unique challenges in balancing new parenthood with work responsibilities, especially upon their return from parental leave. We designed a pilot program that incorporated 1:1 parental coaching to expectant and new physician
Externí odkaz:
https://doaj.org/article/96b8f425dca34855b77b9d21d2c365e0
Publikováno v:
Current Osteoporosis Reports. 21:241-252
Autor:
Jialiang S. Wang, Marc N. Wein
Publikováno v:
Current Osteoporosis Reports. 20:493-504
Purpose of Review The purpose of this review is to discuss the molecular mechanisms involved in osteocyte dendrite formation, summarize the similarities between osteocytic and neuronal projections, and highlight the importance of osteocyte dendrite m
Akademický článek
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Autor:
Cliona O'Farrelly, Brian W. Wong, Min Xu, Ola Ahmed, Yiing Lin, Alexander N Wein, Fangyu Zhou, William C. Chapman, Gundumi A. Upadhya, Li Ye
Publikováno v:
American Journal of Transplantation. 22:58-70
Antioxidant defence mechanisms, such as the nuclear factor-erythroid 2-related-factor-2 (NRF2) axis, are integral to oxidative stress responses and ischemic injury. Hepatic antioxidant capacity is contingent on parenchymal quality, and there is a nee
Autor:
Tadatoshi Sato, Christian D. Castro Andrade, Sung-Hee Yoon, Yingshe Zhao, William J. Greenlee, Patricia C. Weber, Usha Viswanathan, John Kulp, Daniel J. Brooks, Marie B. Demay, Mary L. Bouxsein, Bruce Mitlak, Beate Lanske, Marc N. Wein
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(50)
Osteoporosis is a major public health problem. Currently, there are no orally available therapies that increase bone formation. Intermittent parathyroid hormone (PTH) stimulates bone formation through a signal transduction pathway that involves inhib