High-clearance anti-amyloid immunotherapies in Alzheimer's disease. Part 2: putative scenarios and timeline in case of approval, recommendations for use, implementation, and ethical considerations in France

Autor: N. Villain, V. Planche, R. Levy

Publikováno v: Revue Neurologique. 178:999-1010

In 2021, aducanumab, an immunotherapy targeting amyloid-β, was approved for Alzheimer's disease (AD) by the US Food and Drug Administration thanks to positive results on a putative biological surrogate marker. This approval has raised an unprecedent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee9ed1fe9a3de0a8f0be04126dd2856
https://doi.org/10.1016/j.neurol.2022.08.002

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High-clearance anti-amyloid immunotherapies in Alzheimer's disease. Part 1: Meta-analysis and review of efficacy and safety data, and medico-economical aspects

Autor: N. Villain, V. Planche, R. Levy

Publikováno v: Revue neurologique. 178(10)

In 2021, aducanumab, an immunotherapy targeting amyloid-β, was approved for Alzheimer's disease (AD) by the US Food and Drug Administration thanks to positive results on a putative biological surrogate marker. This approval has raised an unprecedent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03615905f552db6d2be41341f5c8226a
https://pubmed.ncbi.nlm.nih.gov/36184326

Pour une prise en charge préventive de la maladie d’Alzheimer

Autor: B, Dubois, S, Bombois, N, Villain, M, Teichmann, S, Epelbaum, R, Migliaccio, R, Genthon, B, Verrat, C, Lesoil, M, Levy, I, Le Ber, R, Levy

Publikováno v: Bulletin de l'Académie Nationale de Médecine
Bulletin de l'Académie Nationale de Médecine, Elsevier Masson, 2020, 204 (6), pp.583-588. ⟨10.1016/j.banm.2020.04.012⟩

International audience; Dementias, and Alzheimer's disease (AD) in particular, will increasingly become a public health issue. However, three major data may change the severity of these pathologies: in young adults, simple measures of healthy lifesty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4361d7319e021311a04d10a7b8286897
https://hal.sorbonne-universite.fr/hal-03017146/document

Carotid contrast-enhanced ultrasonography and multimodal imaging in a case of TIPIC syndrome

Autor: N. Villain, J.-M. Baud, Fernando Pico, R El Nawar, M. de Malherbe

Publikováno v: Revue Neurologique. 174:304-307

Transient perivascular inflammation of the carotid artery (TIPIC) syndrome, previously referred to as 'carotidynia', is an unclassified clinicoradiological entity associating atypical acute neck pain, eccentric perivascular infiltration on imaging an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55cb88b384c29b88106dbe47205e0d61
https://doi.org/10.1016/j.neurol.2018.01.367