Zobrazeno 1 - 10
of 298
pro vyhledávání: '"N. Vande Casteele"'
Akademický článek
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Autor:
V Solitano, D F Schaeffer, M Hogan, R K Pai, G Zou, N Vande Casteele, C E Parker, J Remillard, B Christensen, R Panaccione, B E Sands, G D’Haens, B G Feagan, C Ma, V Jairath
Publikováno v:
Journal of Crohn's and Colitis. 17:i608-i609
Background The operating properties of histologic indices are poorly characterized in Crohn’s disease (CD) and no validated index exists. We assessed the reliability and responsiveness of histologic indices/items, developed an exploratory index, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56e4c7290bcb1bfe3517020df9522313
https://doi.org/10.1093/ecco-jcc/jjac190.0609
https://doi.org/10.1093/ecco-jcc/jjac190.0609
Autor:
T P Stern, P W Krzeski, D Cui, N. Vande Casteele, P G Traber, Jennifer Jones, P G Linde, C L Soo, H Nguyen, G Bain, M M Mangada, A S Ray, B N Rogers, M M Reardon, D Lee, L H Vrishabhendra
Publikováno v:
Journal of Crohn's and Colitis. 15:S333-S335
Background MORF-057 is an orally administered small molecule designed to inhibit the α 4β 7 receptor, addressing an unmet medical need in inflammatory bowel disease (IBD) patients, and avoiding the need for periodic therapeutic infusions and the ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd90790d0257a60bdbdcfb1773d64c69
https://doi.org/10.1093/ecco-jcc/jjab076.430
https://doi.org/10.1093/ecco-jcc/jjab076.430
Autor:
W J Sandborn, N. Vande Casteele, Geert D'Haens, Reena Khanna, Brian G. Feagan, Rish K. Pai, Christopher Ma, Vipul Jairath, Leonardo Guizzetti, Remo Panaccione, Claire E Parker, Richard N. Fedorak, Tran M Nguyen
Publikováno v:
Alimentary Pharmacology & Therapeutics. 47:1578-1596
Background: Regulatory requirements for claims of mucosal healing in ulcerative colitis (UC) will require demonstration of both endoscopic and histologic healing. Quantifying these rates is essential for future drug development. Aims: To meta-analyse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adee36a3f5fcc324005323a0fe42a02d
https://doi.org/10.1111/apt.14672
https://doi.org/10.1111/apt.14672
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Divine Tanyingoh, Cynthia H. Seow, Gurmeet K. Bindra, M J Stewart, Subrata Ghosh, Remo Panaccione, N. Vande Casteele, Paul L. Beck, Gilaad G. Kaplan, E. Ehteshami Afshar, Yvette Leung
Publikováno v:
Alimentary Pharmacology & Therapeutics. 45:1329-1338
Background Transplacental transfer of infliximab and adalimumab results in detectable drug levels in the cord blood and infant. Aim To determine if pregnancy influenced the pharmacokinetics of anti-TNF agents in women with inflammatory bowel disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856ad80d9a349283fc903d453f024b6f
https://doi.org/10.1111/apt.14040
https://doi.org/10.1111/apt.14040
Autor:
Akshay Buch, Michael Allen Flynn, Debbie Slee, C Van Biene, Jinshan Shen, Kevin Peters, K Taylor Meadows, Allan Olson, Richard Aranda, Gregory J. Opiteck, Barrett G. Levesque, N. Vande Casteele
Publikováno v:
Journal of Crohn's and Colitis. 14:S461-S462
Background GB004 is a small-molecule prolyl hydroxylase inhibitor that stabilises hypoxia-inducible factors (HIF-1α), key transcription factors involved in the protective cellular responses at the intersection of hypoxia and inflammation. GB004 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::729ef44e2056a0d902f8bb4377060d8f
https://doi.org/10.1093/ecco-jcc/jjz203.668
https://doi.org/10.1093/ecco-jcc/jjz203.668
Autor:
Neeraj Narula, Vipul Jairath, Christopher Ma, Severine Vermeire, W J Sandborn, Brian G. Feagan, S Singh, G. D'Haens, L Peyrin-Biroulet, N. Vande Casteele, Parambir S. Dulai
Publikováno v:
Journal of Crohn's and Colitis. 14:S196-S196
Background We aimed to quantify the prevalence of endoscopic improvement (EI) and remission (ER) amongst ulcerative colitis patients with various permutations of patient reported outcomes (PRO) following treatment with biologic agents or tofacitinib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d74e6230ad2a91d6e17b849d393f5c12
https://doi.org/10.1093/ecco-jcc/jjz203.249
https://doi.org/10.1093/ecco-jcc/jjz203.249
Autor:
N. Vande Casteele, S Singh, W J Sandborn, Eduardo Grunvald, Amir Zarrinpar, Elisabeth Evans, Parambir S. Dulai, Soumya Kurnool, James A. Proudfoot, Nghia Nguyen, Brigid S. Boland
Publikováno v:
Alimentary pharmacology & therapeutics, vol 47, iss 11
Background Though pharmacokinetic studies suggest accelerated biologic drug clearance with increasing body weight, evidence of obesity's impact on clinical outcomes in biologic-treated patients with ulcerative colitis (UC) is inconsistent. Aim To eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a634628bc2ce8e8658de650a8c58ee96
https://escholarship.org/uc/item/96j114qc
https://escholarship.org/uc/item/96j114qc
