Zobrazeno 1 - 10
of 27
pro vyhledávání: '"N. V. S. Ramakrishna"'
Publikováno v:
Chromatographia. 63:135-141
A simple, rapid, sensitive and selective liquid chromatography / tandem mass spectrometry method was developed and validated for the quantification of pentoxifylline, a haemorheological agent. The analyte and internal standard, tamsulosin were extrac
Autor:
N. V. S. RamaKrishna, Eleanor G. Rogan, Prabhakar D. Devanesan, Patrick P.J. Mulder, Ercole L. Cavalieri
Publikováno v:
Polycyclic Aromatic Compounds. 7:129-136
Benzo[a]pyrene (BP) is a good model for elucidating the mechanism of oxygen transfer for substrates that are considered good electron donors. Fluoro substitution of BP represents a suitable probe for studying mechanisms of oxygen transfer in the meta
Autor:
N. V. S. RamaKrishna, Eleanor G. Rogan, Rosa Todorovic, George P. Casale, Ercole L. Cavalieri
Publikováno v:
Polycyclic Aromatic Compounds. 6:53-61
Nearly 80% of benzo[a]pyrene (BP)-DNA adducts are lost by depurination and excreted in the urine. These adducts offer a unique opportunity for biomonitoring BP exposure, although their hydrophobic nature poses challenges for methods development. We h
Autor:
Paolo Cremonesi, Ercole L. Cavalieri, N. V. S. RamaKrishna, Eleanor G. Rogan, Patrick P.J. Mulder
Publikováno v:
Chemical Research in Toxicology. 6:657-661
Fluoro-substituted aromatic hydrocarbons are useful probes for studying mechanistic details of oxygen transfer in metabolism catalyzed by cytochrome P450. Benzo[a]pyrene (BP) is a particularly suitable substrate for investigating this mechanism. Beca
Autor:
Ercole L. Cavalieri, Eleanor G. Rogan, Sheila Higginbotham, N. V S RamaKrishna, Sonny L. Johansson
Publikováno v:
Carcinogenesis. 14:875-878
Dibenzo[a,l]pyrene (DB[a,l]P) is an extremely potent carcinogen that may be present in environmental samples. Dose-response studies were conducted at low doses in mouse skin by initiation-promotion and repeated application to compare its activity to
Autor:
Shashidhar V. Karpurmath, P. Rojaramani, K.V. Santosh, N. V. S. Ramakrishna, Manjunath Nandennavar
Publikováno v:
Indian Journal of Medical and Paediatric Oncology : Official Journal of Indian Society of Medical & Paediatric Oncology
Autor:
N. V. S. RamaKrishna, Eleanor G. Rogan, Ercole L. Cavalieri, Michael L. Gross, Ryszard Jankowiak, Ronald L. Cerny, H. Jeong, G. Dolnikowski, Gerald J. Small
Publikováno v:
ChemInform. 23
Anodic oxidation of 7,12-dimethylbenz[a]anthracene (7,12-DMBA) in the presence of dG yields four adducts and one oxygenated derivative of 7,12-DMBA: 7-methylbenz[a]anthracene (MBA)-12-CH 2 -C8dG (13%), 7-MBA-12-CH 2 -N7Gua (55%), 12-MBA-7-CH 2 -N7Gua
Publikováno v:
ChemInform. 30
Autor:
N V S Ramakrishna, R. V. S. V. Vadlamudi, Tulsidas Sitaram More, Yatendra Dr. Khandelwal, Ramchandra Ganapati Dr Naik, Bansi Lal, R. D. Gupte
Publikováno v:
ChemInform. 31
Autor:
N. V S RamaKrishna, Ercole L. Cavalieri, Terence Lawson, Carol Kolar, Eleanor G. Rogan, Luis Eduardo Soares Netto, Ohara Augusto
Publikováno v:
Journal of Biological Chemistry. 267:21524-21527
C8-Methylguanine was identified in the neutral hydrolysates of DNA isolated from the liver or colon tissue of rats administered 1,2-dimethylhydrazine. In all the samples examined, the biologically isolated adducts were characterized by co-elution wit