Zobrazeno 1 - 10
of 76
pro vyhledávání: '"N. V. Medunitsyn"'
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 20, Iss 1, Pp 21-29 (2020)
The review is devoted to specific aspects of the development of post-vaccination immunity following immunisation with different types of antiviral vaccines, as well as to ways of increasing immunogenicity of vaccines and effectiveness of preventive v
Externí odkaz:
https://doaj.org/article/868460d801524885a171b14115589023
Autor:
Zh. I. Avdeeva, N. A. Alpatova, V. P. Bondarev, R. A. Volkova, N. I. Lonskaya, E. V. Lebedinskaya, N. V. Medunitsyn, A. N. Mironov, N. A. Ozeretskovsky, A. A. Soldatov, V. A. Shevtsov
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 0, Iss 1, Pp 15-20 (2018)
The paper presents the data on safety and efficacy assessment of adjuvants and vaccines with adjuvants at the stages of development and preclinical studies based on international recommendations. The presence of an adjuvant in vaccine content ensures
Externí odkaz:
https://doaj.org/article/1f738af181434314a0806ec47f8d64dc
Autor:
Zh. I. Avdeeva, A. A. Soldatov, N. A. Alpatova, M. V. Kiselevsky, S. L. Lysikova, V. P. Bondarev, N. V. Medunitsyn, V. D. Mosyagin, V. A. Merkulov, A. N. Mironov
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 0, Iss 1, Pp 4-14 (2018)
The article describes general principles of evidence-based quality assessment research of a recombinant granulocyte colony stimulating factor preparation (G-CSF) under development as well as a confirmation of its similarity to reference preparation (
Externí odkaz:
https://doaj.org/article/32d1b22672a74dfc8c9d6bb84302f9fe
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 0, Iss 3, Pp 4-16 (2018)
One of the most complicated issues of modern medicine is diagnosis, treatment and prevention of rare diseases. In the structure of rare diseases the vast majority accounts for genetically determined disorders. The introduction of genetic testing meth
Externí odkaz:
https://doaj.org/article/529672b09bd64b58911646911672a181
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 16, Iss 4, Pp 195-207 (2018)
The present article adduces the evidence in support of the need in the development of personalized vaccines and provides with case studies, substantiating the possibility of the mentioned approach. In order to personalize vaccines one should perform
Externí odkaz:
https://doaj.org/article/ab21f28c6044456bba5e3ccfd417ff7c
Autor:
Yu. V. Olefir, N. V. Medunitsyn, Zh. I. Avdeeva, A. A. Soldatov, A. A. Movsesyants, V. A. Merkulov, V. P. Bondarev
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 16, Iss 2, Pp 67-77 (2018)
The review provides with the information, related to the development, research and registration of new biological preparations, including the issues of terminology and classification. It also highlights the issues of and prospects for genetically eng
Externí odkaz:
https://doaj.org/article/8b8911179d864f67ba55d80a4379a8f2
Autor:
Zh. I. Avdeeva, A. A. Soldatov, N. A. Alpatova, N. V. Medunitsyn, V. P. Bondarev, A. N. Mironov, V. A. Merkulov, I. V. Sakaeva
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 0, Iss 1, Pp 21-35 (2018)
The article provides the information on issues related to the clinical use of preparations of monoclonal antibodies (MAb), and the prospects for developing preparations based on modified MAbs. MAb preparations based on recombinant proteins show the c
Externí odkaz:
https://doaj.org/article/ad276db43143489189576435c079b981
Autor:
Zh. I. Avdeeva, A. A. Soldatov, N. A. Alpatova, V. P. Bondarev, Yu. V. Olefir, V. A. Merkulov, V. D. Mosyagin, N. V. Medunitsyn
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 16, Iss 4, Pp 208-218 (2018)
The review deals with the issues related to the special aspects of the development of the first available similar biopharmaceuticals/biological analogues («biosimilars») based on monoclonal antibodies. In June 2013 the Committee for Medicinal Produ
Externí odkaz:
https://doaj.org/article/bdbd06b93d8e4aa596031bd8c0837f50
Autor:
A. A. Soldatov, Zh. I. Avdeeva, N. A. Alpatova, N. V. Medunitsyn, S. L. Lysikova, V. A. Merkulov
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 0, Iss 2, Pp 24-35 (2018)
Biological preparations differ substantially from low molecular weight chemicals in molecular weight, multidimensional structure of an active substance, presence of post-translational modifications, composition of impurities and excipients, drug manu
Externí odkaz:
https://doaj.org/article/d0ea2a65db944e148348e59e32ca767f
Publikováno v:
Pharmaceutical Chemistry Journal. 53:991-996
Vaccinal prophylaxis is the most effective way to reduce incidence rates. However, the immune response developing after injection of most inactivated vaccines is insufficient when used without adjuvants. Special attention should be paid to the issue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39c89c20ac6b697a5047b7ef54668785
https://doi.org/10.1007/s11094-020-02111-3
https://doi.org/10.1007/s11094-020-02111-3