Zobrazeno 1 - 10
of 39
pro vyhledávání: '"N. V. Maluchenko"'
Autor:
T. V. Andreeva, O. V. Chertkov, M. E. Valieva, Elena Kotova, Mikhail P. Kirpichnikov, Vasily M. Studitsky, Anastasiia Sivkina, N. V. Maluchenko, Alexey V. Feofanov
Publikováno v:
Microscopy and Microanalysis. 28:243-253
Inorganic ions are essential factors stabilizing nucleosome structure; however, many aspects of their effects on DNA transactions in chromatin remain unknown. Here, differential effects of K+ and Na+ on the nucleosome structure, stability, and intera
Autor:
Darya O. Koshkina, Mikhail P. Kirpichnikov, N. V. Maluchenko, Alexey V. Feofanov, Vasily M. Studitsky
Publikováno v:
Acta Naturae
Poly(ADP-ribosyl)ation plays a key role in cellular metabolism. Covalent poly(ADP-ribosyl)ation affects the activity of the proteins engaged in DNA repair, chromatin structure regulation, gene expression, RNA processing, ribosome biogenesis, and prot
Autor:
Sohail Akhtar, John M. Pascal, N. S. Gerasimova, Elena Kotova, Mikhail P. Kirpichnikov, D. K. Nilov, Marie-France Langelier, Sergey Pushkarev, N. V. Maluchenko, Alexey V. Feofanov, Vasily M. Studitsky
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12127, p 12127 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences
Volume 22
Issue 22
Poly(ADP-ribose) polymerase 1 (PARP1) is an enzyme involved in DNA repair, chromatin organization and transcription. During transcription initiation, PARP1 interacts with gene promoters where it binds to nucleosomes, replaces linker histone H1 and pa
Autor:
Vasily M. Studitsky, Tatiana Andreeva, Alexey V. Feofanov, O. V. Chertkov, Mikhail P. Kirpichnikov, N. V. Maluchenko
Publikováno v:
Microscopy and Microanalysis. 26:1390-1392
Abstract P-24: Microscopic Analyses of Liquid-Liquid Phase Separation Induced by Linker Histone H1.0
Autor:
Daria Koshkina, Vasily M. Studitsky, N. S. Gerasimova, N. V. Maluchenko, Olga Geraskina, Alexey V. Feofanov
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss Suppl_1, Pp 21-22 (2021)
Background: Liquid-liquid phase separation (LLPS) that leads to the formation of temporary functional domains in cells plays an important role in the processes of chromatin condensation and gene regulation. Earlier, it was demonstrated that histone H
Autor:
Tatyana A. Kurgina, N. S. Gerasimova, Mikhail A. Kutuzov, N. V. Maluchenko, Vasily M. Studitsky, Alexandra Lys, Olga I. Lavrik, Sergey Pushkarev, Alexey V. Feofanov, Vytas K. Švedas, D. K. Nilov
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2159 (2020)
International Journal of Molecular Sciences; Volume 21; Issue 6; Pages: 2159
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2159 (2020)
International Journal of Molecular Sciences; Volume 21; Issue 6; Pages: 2159
7-Methylguanine (7-MG), a natural compound that inhibits DNA repair enzyme poly(ADP-ribose) polymerase 1 (PARP-1), can be considered as a potential anticancer drug candidate. Here we describe a study of 7-MG inhibition mechanism using molecular dynam
Publikováno v:
Molecular Biology. 52:637-647
Publikováno v:
Молекулярная биология. 52:737-749
HMGB proteins are involved in structural rearrangements caused by regulatory chromatin remodeling factors. Particular interest is attracted to a DNA chaperone mechanism, suggesting that the HMGB proteins introduce bends into the double helix, thus re
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 11441, p 11441 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 11441, p 11441 (2021)
Poly (ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme involved in processes of cell cycle regulation, DNA repair, transcription, and replication. Hyperactivity of PARP-1 induced by changes in cell homeostasis promotes development of chronic pat
Autor:
Igor I. Agapov, N. V. Maluchenko, A. Y. Arkhipova, Sergei A. Nedospasov, M. S. Drutskaya, M. A. Nosenko, Mikhail M. Moisenovich
Publikováno v:
Acta Naturae. 9:89-93
Culturing of allogeneic or autologous cells in three-dimensional bioresorbable scaffolds is an important step in the engineering of constructs for regenerative medicine, as well as for experimental systems to study the mechanisms of cell differentiat