Zobrazeno 1 - 10
of 31
pro vyhledávání: '"N. V. LATYSHKO"'
Publikováno v:
Biotechnologia Acta, Vol 16, Iss 2, Pp 42-43 (2023)
The aim of the present study was to find out the role of Ruk/CIN85 in modulation of activities/content of key enzymes/components of glycolysis and hydrogen peroxide using as a model human NSCLC MOR wild type and resistant to drugs MOR/0.2R cells. M
Externí odkaz:
https://doaj.org/article/dba8ed4a9a914cd1867fcd368692457b
Publikováno v:
The Ukrainian Biochemical Journal, Vol 93, Iss 5, Pp 72-81 (2021)
The pathogenesis of pulmonary fibrosis (PF) is accompanied by extracellular matrix (ECM) deposition, oxidative stress, and inflammation progression, as well as hyperactivation of amine oxidases (AOs), which contribute to disease manifestation. The pr
Externí odkaz:
https://doaj.org/article/621ee24ca556462c8eb2757b2cc2b331
Autor:
I. R. Horak, N. V. Latyshko, O. O. Hudkova, T. O. Kishko, O. V. Khudiakova, D. S. Gerashchenko, T. D. Skaterna, I. P. Krysiuk, S. G. Shandrenko, L. B. Drobot
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 4, Pp 24-34 (2020)
Excessive reactive oxygen species (ROS) production may lead to damage of cellular proteins, lipids and DNA, and cause cell death. Our previous findings demonstrated that increased level of adaptor protein Ruk/CIN85 contributes to breast cancer cells
Externí odkaz:
https://doaj.org/article/d39bb56abc58455395cdfd914ea7e1d2
ADAPTOR PROTEIN RUK/CIN85 IS INVOLVED IN THE GLUCOSE METABOLISM REPROGRAMMING IN BREAST CANCER CELLS
Autor:
M. I. Bekala, I. R. Horak, O. O. Gudkova, N. V. Latyshko, K. O. Tokarchuk, D. S. Geraschenko, M. O. Shkoda, L. B. Drobot
Publikováno v:
Biotechnologia Acta, Vol 15, Iss 2, Pp 47-48 (2022)
Aim. This study aimed to investigate the changes in glucose metabolism in mouse 4T1 breast adenocarcinoma cells with different levels of Ruk/CIN85 expression. Methods. We used 4T1 cells with stable overexpression (subline RukUp) or knockdown (subl
Externí odkaz:
https://doaj.org/article/9a3994bba538451a9199281fa347f1b0
Publikováno v:
Biotechnologia Acta, Vol 15, Iss 2, Pp 58-59 (2022)
Aim. To determine the role of Ruk/CIN85 in the control of breast adenocarcinoma cells metabolism, we performed systemic analysis of the activity levels/content of key enzymes/components of glycolysis and oxidative phosphorylation using as a model the
Externí odkaz:
https://doaj.org/article/327ddc41ed3940568b80109047e59afa
Publikováno v:
The Ukrainian Biochemical Journal, Vol 90, Iss 5, Pp 98-105 (2018)
The goal of the present study was to extract and purify lysyl oxidase from rodent’s tissues by a fast, simple, effective and inexpensive method and to develop a sensitive, time-saving lysyl oxidase specific activity assay for routine in vitro exper
Externí odkaz:
https://doaj.org/article/f205908d03ed425f8a0a6590c69bc313
Publikováno v:
The Ukrainian Biochemical Journal, Vol 88, Iss 1, Pp 79-87 (2016)
In this study we have tested an idea on the important role of amine oxidases (semicarbazide-sensitive amine oxidase, diamine oxidase, polyamine oxidase) as an additional source of oxidative/carbonyl stress under glycerol-induced rhabdomyolysis, since
Externí odkaz:
https://doaj.org/article/646a45288813436184edd3bee9d0e2f0
Publikováno v:
The Ukrainian Biochemical Journal, Vol 87, Iss 3, Pp 75-90 (2015)
This work is devoted to the study of the features of oxidative metabolism of hepatocytes in diabetic mice and those under the vitamin D3 action. We found out that a 2.5-fold decrease of 25OHD3 content in the serum was caused by chronic hyperglycemia
Externí odkaz:
https://doaj.org/article/e8fcf399157e4fc590d7c9b97596db3e
Publikováno v:
Ukrainian Biochemical Journal, Vol 93, Iss 5, Pp 72-81 (2021)
The pathogenesis of pulmonary fibrosis (PF) is accompanied by extracellular matrix (ECM) deposition, oxidative stress, and inflammation progression, as well as hyperactivation of amine oxidases (AOs), which contribute to disease manifestation. The pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13af8c61773f88bb9b6319dfa931f85d
http://ukrbiochemjournal.org/wp-content/uploads/2021/10/Hudkova_5_21.pdf
http://ukrbiochemjournal.org/wp-content/uploads/2021/10/Hudkova_5_21.pdf
Autor:
I R, Horak, N V, Latyshko, O O, Hudkova, K O, Tokarchuk, T O, Kishko, O I, Yusova, L B, Drobot, A A, Tykhomyrov
Publikováno v:
Experimental oncology. 44(1)
Cell surface plasmin is involved in tumor growth and metastatic dissemination by regulating cancer cells adhesion, migration and invasion. Plasmin-induced cell detachment is accompanied by an increased rate of reactive oxygen species (ROS) generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2950ed062a4890cee1a10f421e56ea41
https://pubmed.ncbi.nlm.nih.gov/35548969
https://pubmed.ncbi.nlm.nih.gov/35548969