Zobrazeno 1 - 10
of 71
pro vyhledávání: '"N. V. Kandalintseva"'
Publikováno v:
Сибирский научный медицинский журнал, Vol 43, Iss 5, Pp 127-134 (2023)
TS-13 (sodium 3-(3’-tert-butyl-4’-hydroxyphenyl)propylthiosulfonate) is a synthetic antioxidant that has demonstrated biological effectiveness in numerous studies in modeling pathological conditions in vivo, in particular, in the model of Parkins
Externí odkaz:
https://doaj.org/article/ac9214d960014da384b5aac1afa2b216
Autor:
E. B. Menshchikova, R. A. Knyazev, N. V. Trifonova, N. A. Deeva, A. R. Kolpakov, L. P. Lidia P. Romakh, N. V. Kandalintseva
Publikováno v:
Сибирский научный медицинский журнал, Vol 43, Iss 5, Pp 108-117 (2023)
The antitumor antibiotic doxorubicin, a representative of a large group of anthriacyclines, is widely and quite effectively used to treat patients with malignant neoplasms. The aim of this study was to study the effect of TS-13, a synthetic phenolic
Externí odkaz:
https://doaj.org/article/c5229a4af04b43fb9232eac5a11fa178
Autor:
P. M. Kozhin, A. S. Sementsov, S. E. Khrapov, M. V. Khrapova, L. P. Romakh, N. V. Kandalintseva, E. B. Menshchikova
Publikováno v:
Сибирский научный медицинский журнал, Vol 42, Iss 6, Pp 35-44 (2022)
Oxidative stress is an important mechanism of myocardial damage during ischemia/reperfusion. To investigate the possibility of restoring the redox balance using “indirect” antioxidant effects, the cardioprotective effect Keap1/Nrf2/ ARE system in
Externí odkaz:
https://doaj.org/article/35454f24c9b044708ecf9413609656c3
Autor:
M. V. Khrapova, S. E. Khrapov, A. V. Chechushkov, P. M. Kozhin, L. P. Romakh, A. E. Serykh, S. V. Kholshin, N. V. Kandalintseva, E. B. Menshchikova
Publikováno v:
Сибирский научный медицинский журнал, Vol 42, Iss 5, Pp 11-18 (2022)
One of the promising areas of modern pharmacology is the development of «indirect antioxidants» capable of activating redox-sensitive signaling systems, primarily the Keap1/Nrf2/ARE system. Among its chemical inductors is the hydrophilic monosubsti
Externí odkaz:
https://doaj.org/article/64f0c7ef199e4899abed2cc09b3ca94e
Autor:
T. G. Shinko, S. V. Terentyeva, S. Ye. Yagunov, N. V. Kandalintseva, O. I. Prosenko, Ye. A. Ivanovskaya, P. I. Pinko
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 11, Iss 1, Pp 106-112 (2022)
Introduction. Dodecyl(3,5-dimethyl-4-hydroxybenzyl)sulfide (T1) and bis-[3-(3,5-di-tert-butyl-4-hydroxyphenyl)propyl]sulfide (T2) are the collaborative development of Novosibirsk State Pedagogical University and Novosibirsk Research Institute of Anti
Externí odkaz:
https://doaj.org/article/d32ee689228d489dac84c98fce00cb67
Autor:
E. B. Menshchikova, N. K. Zenkov, P. M. Kozhin, A. V. Chechushkov, V. S. Pavlov, L. P. Romakh, M. V. Khrapova, A. E. Serykh, O. B. Gritsyk, N. V. Kandalintseva
Publikováno v:
Сибирский научный медицинский журнал, Vol 40, Iss 6, Pp 58-69 (2020)
Understanding the role of reactive oxygen and nitrogen species in eustress (redox balance) and distress (oxidative stress) development poses new challenges for biomedical scientists and pharmacologists in the search for compounds that can not only ha
Externí odkaz:
https://doaj.org/article/d474da70577948f88ecfc58d526ab64c
Autor:
N. K. Zenkov, A. V. Chehushkov, P. M. Kozhin, G. G. Martinovich, N. V. Kandalintseva, E. B. Menshchikova
Publikováno v:
Бюллетень сибирской медицины, Vol 18, Iss 2, Pp 195-214 (2019)
Autophagy is the main catabolic process required for the removal of damaged organelles, aggregated proteins and intracellular pathogens from cells. Oxidative stress is accompanied by an increase in autophagy, which has a protective effect by maintain
Externí odkaz:
https://doaj.org/article/3dd073a9e9164a6eaa1e66ede1017681
Autor:
N. K. Zenkov, P. M. Kozhin, A. V. Vcherashnyaya, G. G. Martinovich, N. V. Kandalintseva, E. B. Menshchikova
Publikováno v:
Сибирский научный медицинский журнал, Vol 39, Iss 2, Pp 11-26 (2019)
Endogenous mechanisms of reactive oxygen (ROS) and nitrogen species production and of antioxidant defense systems in tumor cells are analyzed. Increased ROS production is an important regulator of metabolic changes in these cells: enhanced proliferat
Externí odkaz:
https://doaj.org/article/57059c42a168468798b406cd20866ae2
Autor:
P. I. Gaynutdinov, P. M. Kozhin, A. V. Chechushkov, G. G. Martinovich, S. V. Kholshin, N. V. Kandalintseva, N. K. Zenkov, E. B. Menshchikova
Publikováno v:
Сибирский научный медицинский журнал, Vol 38, Iss 1, Pp 22-31 (2019)
The aim of the study was to study investigate the relationship between the antioxidant activity of new synthetic structurally related water-soluble monophenols and their effect on the tumor cell viability in vitro. Material and methods. Five original
Externí odkaz:
https://doaj.org/article/9aee845f3df24acb8dba91409904e7aa
Autor:
P. M. Kozhin, A. V. Kovner, N. K. Zenkov, T. I. Petrenko, N. V. Kandalintseva, E. B. Menshchikova
Publikováno v:
Сибирский научный медицинский журнал, Vol 38, Iss 1, Pp 5-11 (2019)
The aim of the study was to determine the dose of a virulent strain of Mycobacterium tuberculosis H37Rv that is optimal for modeling experimental tuberculosis granulomatosis in mice and to investigate the effect of the original inductor of the Keap1/
Externí odkaz:
https://doaj.org/article/fb15bafe3f554f38b02d0fdfff4dddff