Zobrazeno 1 - 10
of 18
pro vyhledávání: '"N. V. Dozmorova"'
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 12, Iss 4, Pp 151-155 (2023)
Introduction. The hemostasis system is a set of functional, morphological and biochemical mechanisms of a living organism that ensure the preservation of the liquid state of the blood, the prevention and stopping of bleeding, as well as the integrity
Externí odkaz:
https://doaj.org/article/313f552c06964e1d8ce5484c394e17a3
Autor:
N. A. Buzmakova, K. V. Аndryukov, T. M. Zamaraeva, I. P. Rudakova, K. V. Podchezertseva, A. S. Goman, E. V. Avdeeva, N. V. Slepova, N. V. Dozmorova
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 12, Iss 4, Pp 13-18 (2023)
Introduction. Molecular modeling methods are very popular in the scientific community at the present time. The value of the pharmacological action depends on the affinity of the substance to the biological target. Molecular docking makes it possible
Externí odkaz:
https://doaj.org/article/662070420d4a4d309e728bdbc9ed3005
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 12, Iss 4, Pp 78-83 (2023)
Introduction. Vascular pathologies associated with thromboembolism are common complications and the leading cause of morbidity and mortality among patients of various nosological groups. Previously, we obtained water-soluble 2-hydroxy-4-oxo-4-R-2-but
Externí odkaz:
https://doaj.org/article/8fc1525a2d174d089e7127f4370d0c76
Autor:
E. Yu. Avdeeva, N. M. Igidov, V. L. Gein, S. V. Krivoshchekov, I. A. Khlusov, M. V. Belousov, N. V. Dozmorova, V. G. Luzhanin
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 12, Iss 4, Pp 47-52 (2023)
Introduction. Osteogenic agents are used for pathologies associated with impaired bone formation, complications of bone fractures, the use of implants and endoprostheses, and tumor lesions of bone tissue. High osteogenic activity in vivo on the model
Externí odkaz:
https://doaj.org/article/9cdb4ed9e98343f0b8d8bb5b874f8536
Autor:
N. A. Buzmakova, T. M. Zamaraeva, D. Yu. Ivkin, D. Yu. Apushkin, N. V. Slepova, N. V. Dozmorova
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 12, Iss 4, Pp 112-118 (2023)
Introduction. Antioxydant activity, membrane stabilizing and cytoprotective effect of dihydropyrimidin analoges are widely described in various literary sources. One of the importantant mechanisms of action of antioxidants is their antihypoxic activi
Externí odkaz:
https://doaj.org/article/e4702b157193460c8645fbbb72e937e5
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 11, Iss 4, Pp 64-67 (2022)
Introduction. COVID-19 is recognized as the most significant pandemic of the modern era. Studies have shown the potential benefits of taking ascorbic acid in the complex treatment of this disease, especially in people with vitamin C deficiency. One o
Externí odkaz:
https://doaj.org/article/2a3fae9364e64751bb968f37274cb8ef
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 11, Iss 4, Pp 38-42 (2022)
Introduction. New potential biologically active compounds with different pharmacological activities were found among pyrimidine derivatives. Simple and available synthesis of tetrahydropyrimidine-5-carboxamides was developed in Perm State Pharmaceuti
Externí odkaz:
https://doaj.org/article/25dc06f70f7449558f1c4311420a790b
Autor:
O. A. Eliseeva, M. A. Kolganova, I. E. Shokhin, S. P. Dementyev, A. M. Vlasov, A. A. Zamyatnin, N. S. Dubovik, A. Yu. Savchenko, N. V. Dozmorova, V. G. Luzhanin
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 11, Iss 4, Pp 120-127 (2022)
Introduction. One of the widely used specific anti-HER2 (human epidermal growth factor receptor 2) MAb drugs is trastuzumab. Trastuzumab is highly effective for malignant HER2 hyperexpression reduction, which results in HER2 oncogenicity decrease. As
Externí odkaz:
https://doaj.org/article/85fbef26ae0b43768284bd0f5f5380bc
Publikováno v:
Russian Journal of General Chemistry. 90:2225-2229
5-Aryl-4-aroyl-3-hydroxy-1-cyanomethyl-3-pyrrolin-2-ones were synthesized by a three-component reaction of aroylpyruvic acid methyl ester with a mixture of aromatic aldehyde and 2-aminoacetonitrile sulfate in glacial acetic acid in the presence of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fd1edbee2bc106edc482299054d4028
https://doi.org/10.1134/s1070363220120026
https://doi.org/10.1134/s1070363220120026
Publikováno v:
RUDN Journal of Medicine, Vol 0, Iss 4, Pp 199-202 (2010)
Tests by method «speed test to stabilities» were installed with the aim of study of expiration date of new biologically active substance (ВAS) - N-2 (2'-methylphenoxy)-ethylmorpholine hydrochloride, which are shown high antihypertensive activity.
Externí odkaz:
https://doaj.org/article/f1508d2017d642be841391572ee381de