Zobrazeno 1 - 10
of 476
pro vyhledávání: '"N. Talaty"'
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1180 (2022)
(1) Imaging of pharmaceutical compounds in tissue is an increasingly important subsection of Mass Spectrometry Imaging (MSI). Identifying proper target engagement requires MS platforms with high sensitivity and spatial resolution. Three prominent cat
Externí odkaz:
https://doaj.org/article/79ce490f354548acbe8d3e4dea6c435d
Autor:
Darren C. Phillips, Joel D. Leverson, Erwin R. Boghaert, Larry R. Solomon, Yu Xiao, Nari N. Talaty, Relja Popovic, Julie J. Purkal, Dan Cojocari, Sha Jin
Purpose:Patients with acute myeloid leukemia (AML) frequently do not respond to conventional therapies. Leukemic cell survival and treatment resistance have been attributed to the overexpression of B-cell lymphoma 2 (BCL-2) and aberrant DNA hypermeth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abb3f6d9db0b2002b58fae9f47efdb5
https://doi.org/10.1158/1078-0432.c.6529499
https://doi.org/10.1158/1078-0432.c.6529499
Autor:
Darren C. Phillips, Joel D. Leverson, Erwin R. Boghaert, Larry R. Solomon, Yu Xiao, Nari N. Talaty, Relja Popovic, Julie J. Purkal, Dan Cojocari, Sha Jin
Supplementary Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10fc50e2274bad63d06c5fce8194c767
https://doi.org/10.1158/1078-0432.22476848
https://doi.org/10.1158/1078-0432.22476848
Autor:
Darren C. Phillips, Joel D. Leverson, Erwin R. Boghaert, Larry R. Solomon, Yu Xiao, Nari N. Talaty, Relja Popovic, Julie J. Purkal, Dan Cojocari, Sha Jin
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee575ae04102b81e40e82cbd5c2e592
https://doi.org/10.1158/1078-0432.22476851
https://doi.org/10.1158/1078-0432.22476851
Autor:
Fan Pu, Scott A. Ugrin, Andrew J. Radosevich, David Chang-Yen, James W. Sawicki, Nari N. Talaty, Nathaniel L. Elsen, Jon D. Williams
Publikováno v:
Analytical chemistry. 94(39)
Mass spectrometry (MS) is the primary analytical tool used to characterize proteins within the biopharmaceutical industry. Electrospray ionization (ESI) coupled to liquid chromatography (LC) is the current gold standard for intact protein analysis. H
Autor:
Yevgeniya E. Koshman, Aimee L. Bielinski, Brandan M. Bird, Jonathon R. Green, Kenneth L. Kowalkowski, Jie Lai-Zhang, Prathap Kumar Mahalingaiah, James W. Sawicki, Nari N. Talaty, Amanda S. Wilsey, Mark T. Zafiratos, Terry R. Van Vleet
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 120:107251
Publikováno v:
F1000Research, Vol 5 (2016)
This review covers recent advances in the implementation of enabling chemistry technologies into the drug discovery process. Areas covered include parallel synthesis chemistry, high-throughput experimentation, automated synthesis and purification met
Externí odkaz:
https://doaj.org/article/bb1446431bde426eaa45879386fdbf34
Publikováno v:
Toxicology and Applied Pharmacology. 415:115439
Non-genotoxic carcinogens (NGCs) are known to cause perturbations in DNA methylation, which can be an early event leading to changes in gene expression and the onset of carcinogenicity. Phenobarbital (PB) has been shown to alter liver DNA methylation
Autor:
Nari N. Talaty, Dean M. Giolando
Publikováno v:
Zeitschrift für anorganische und allgemeine Chemie. 642:231-238
Atmospheric pressure chemical vapor deposition (APCVD) employing the precursor system of tin tetrachloride, ethyl formate, and 2,2,2-trifluoroethyl trifluoroacetate vapors that were transported to hot glass substrates to deposit fluorine doped tin di
Publikováno v:
Poultry Science. 88:1963-1974
The variability of bone traits was assessed in purebred lines of meat-type chickens using dual-energy x-ray absorptiometry. Experiment 1 evaluated changes in bone mineralization and size traits of the tibia and humerus in 4 purebred lines from 6 to 2