Zobrazeno 1 - 10
of 25
pro vyhledávání: '"N. Takenouchi-Ohkubo"'
Autor:
Akihito Sawada, N. Takenouchi-Ohkubo, Itaru Moro, Masatake Asano, Tomohiko Ishigami, Shigeki Endo, Daisuke Omagari, Kazuo Komiyama
Publikováno v:
Clinical and Experimental Immunology. 165:85-93
Summary Intestinal epithelial cells (IECs) play an important role in protecting the intestinal surface from invading pathogens by producing effector molecules. IECs are one of the major sources of human beta-defensin 2 (hBD-2), and can produce it in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564c22952beaab3f5ecf7e319f481ece
https://doi.org/10.1111/j.1365-2249.2011.04404.x
https://doi.org/10.1111/j.1365-2249.2011.04404.x
Autor:
Itaru Moro, Jean-Pierre Vaerman, N. Takenouchi-Ohkubo, Kunihiko Kobayashi, Kenji Ishikawa, Yoshitaka Ogura, W. U. Chung-Hsing, Masatake Asano, Hirotsugu Chihaya
Publikováno v:
DNA and Cell Biology. 23:403-411
We established a transient human joining (J)-chain gene expression system in the baby hamster kidney (BHK) cell. The J-chain was detected as a 29-kDa single band on Western blotting. Immunofluorescent staining of the transfectant revealed an exclusiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e2b427eb4b2adeffd2acccdd7155cb0
https://doi.org/10.1089/1044549041474779
https://doi.org/10.1089/1044549041474779
Autor:
Tomihisa Takahashi, Itaru Moro, S. Nagafuchi, Y. Nakamura, S. Nosaka, N. Takenouchi-Ohkubo, M. Suzuki, T. Iwase, T. Yajima
Publikováno v:
Clinical and Experimental Immunology. 137:52-58
SUMMARYWe examined whether or not dietary fructooligosaccharides (FOS) in infancy can have a beneficial effect on the mucosal immune system. Newborn BALB/c mice, accompanied by their dams until 21 days of age, were fed either a control diet based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f28d63a1472ce20161ac51e4f468355
https://doi.org/10.1111/j.1365-2249.2004.02487.x
https://doi.org/10.1111/j.1365-2249.2004.02487.x
Autor:
H. Chihaya, Yoshitaka Ogura, K. Ishikawa, Masatake Asano, W. U. Chung-Hsing, N. Takenouchi-Ohkubo, L. Zhu, Naoyuki Matsumoto, Itaru Moro
Publikováno v:
Scandinavian Journal of Immunology. 58:471-476
Using a recombinant vaccinia virus containing the T7 RNA polymerase, we have established a system for the transient expression of human polymeric immunoglobulin receptor (pIgR) in baby hamster kidney cells, a baby hamster-derived fibroblastic cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41916f9eb79c25632a44e9b7e331fad2
https://doi.org/10.1046/j.1365-3083.2003.01325.x
https://doi.org/10.1046/j.1365-3083.2003.01325.x
Publikováno v:
Immunology. 123(4)
Human polymeric immunoglobulin receptor (pIgR) is present on the surface of glandular epithelium, and it plays a crucial role in the mucosal immune defence. pIgR expression in HT-29 cells is up-regulated by one of the proinflammatory cytokines, tumou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2e48ec235605d728f37eaeb3ca70e3
https://pubmed.ncbi.nlm.nih.gov/17971154
https://pubmed.ncbi.nlm.nih.gov/17971154
Autor:
Yoshitaka Ogura, N. Takenouchi-Ohkubo, Naoyuki Matsumoto, Itaru Moro, Hisashi Suguro, Masatake Asano, Hirofumi Nomura
Human polymeric immunoglobulin receptor (pIgR) was expressed in baby hamster kidney (BHK) cells using a recombinant vaccinia virus transfection system. Cleavage of pIgR on the cell surface was partially inhibited by the proteinase inhibitor, leupepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b451bc067397b4dce3f0068bc9c5013c
https://europepmc.org/articles/PMC1782529/
https://europepmc.org/articles/PMC1782529/
SUMMARYIn this study, the detailed mechanisms for the effects of vitamin A on the expression of polymeric immunoglobulin receptor (pIgR) were examined. Expression of the pIgR by tumour necrosis factor (TNF-α) was enhanced by the addition of all-tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7ced852d3e0e726662b6c56164a990
https://europepmc.org/articles/PMC1808977/
https://europepmc.org/articles/PMC1808977/
Autor:
N. Takenouchi-Ohkubo, Itaru Moro, M. Tsuchiya, Tomihisa Takahashi, Zina Moldoveanu, Jiri Mestecky
Publikováno v:
Immunogenetics. 51(4-5)
We analyzed the mechanism of human polymeric immunoglobulin receptor (pIgR) gene upregulation by tumor necrosis factor (TNF)-alpha. Northern blot analysis showed that the expression of pIgR mRNA was enhanced by TNF-alpha stimulation. This activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041e80379ce85724e174c44c711defdc
https://pubmed.ncbi.nlm.nih.gov/10803841
https://pubmed.ncbi.nlm.nih.gov/10803841
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