Zobrazeno 1 - 10
of 60
pro vyhledávání: '"N. Sumru Bayin"'
Autor:
Reeti Mayur Sanghrajka, Richard Koche, Hector Medrano, Salsabiel El Nagar, Daniel N. Stephen, Zhimin Lao, N. Sumru Bayin, Kai Ge, Alexandra L. Joyner
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107831- (2023)
Summary: The major cause of treatment failure and mortality among medulloblastoma patients is metastasis intracranially or along the spinal cord. The molecular mechanisms driving tumor metastasis in Sonic hedgehog-driven medulloblastoma (SHH-MB) pati
Externí odkaz:
https://doaj.org/article/0ff602ca0cc44d9cb6da3c5af8918d2e
Autor:
Harikrishna Rallapalli, N. Sumru Bayin, Hannah Goldman, Dragan Maric, Brian J. Nieman, Alan P. Koretsky, Alexandra L. Joyner, Daniel H. Turnbull
Publikováno v:
NeuroImage, Vol 276, Iss , Pp 120198- (2023)
Magnetic Resonance Imaging (MRI) resolution continues to improve, making it important to understand the cellular basis for different MRI contrast mechanisms. Manganese-enhanced MRI (MEMRI) produces layer-specific contrast throughout the brain enablin
Externí odkaz:
https://doaj.org/article/f5291e0394464c1ea3b1b8d620ae031f
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Externí odkaz:
https://doaj.org/article/1ebffb0792824d1eb749fc0a120b7c42
Autor:
Aram S. Modrek, Danielle Golub, Themasap Khan, Devin Bready, Jod Prado, Christopher Bowman, Jingjing Deng, Guoan Zhang, Pedro P. Rocha, Ramya Raviram, Charalampos Lazaris, James M. Stafford, Gary LeRoy, Michael Kader, Joravar Dhaliwal, N. Sumru Bayin, Joshua D. Frenster, Jonathan Serrano, Luis Chiriboga, Rabaa Baitalmal, Gouri Nanjangud, Andrew S. Chi, John G. Golfinos, Jing Wang, Matthias A. Karajannis, Richard A. Bonneau, Danny Reinberg, Aristotelis Tsirigos, David Zagzag, Matija Snuderl, Jane A. Skok, Thomas A. Neubert, Dimitris G. Placantonakis
Publikováno v:
Cell Reports, Vol 21, Iss 5, Pp 1267-1280 (2017)
Summary: Low-grade astrocytomas (LGAs) carry neomorphic mutations in isocitrate dehydrogenase (IDH) concurrently with P53 and ATRX loss. To model LGA formation, we introduced R132H IDH1, P53 shRNA, and ATRX shRNA into human neural stem cells (NSCs).
Externí odkaz:
https://doaj.org/article/6c38719ab387499d9cbeaef12ccef89b
Autor:
Mark Bustoros, Cheddhi Thomas, Joshua Frenster, Aram S. Modrek, N. Sumru Bayin, Matija Snuderl, Gerald Rosen, Peter B. Schiff, Dimitris G. Placantonakis
Publikováno v:
Case Reports in Neurological Medicine, Vol 2016 (2016)
Background. Extraosseous Ewing’s sarcoma in the spinal epidural space is a rare malignancy, especially in adults. Case Presentation. A 40-year-old male presented with back pain and urinary hesitancy. MRI revealed a thoracic extradural mass with no
Externí odkaz:
https://doaj.org/article/3450145069b94bc48408eb31a5e18e61
Publikováno v:
Cell. 186:1295-1299
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7c21ddef7f393801effdb8f41892ebb
https://doi.org/10.1016/j.cell.2023.03.002
https://doi.org/10.1016/j.cell.2023.03.002
Autor:
Alexandra L. Joyner, N. Sumru Bayin
Publikováno v:
Development (Cambridge, England). 149(18)
ABSRACT The cerebellum has a simple cytoarchitecture consisting of a folded cortex with three cell layers that surrounds a nuclear structure housing the output neurons. The excitatory neurons are generated from a unique progenitor zone, the rhombic l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f083b6b7578e003afa0960ae37c8d44e
https://pubmed.ncbi.nlm.nih.gov/36172987
https://pubmed.ncbi.nlm.nih.gov/36172987
Autor:
Ross Keller, Makiko Yamada, Daniel Cameron, Hiromichi Suzuki, Reeti Sanghrajka, Jake Vaynshteyn, Jeffrey Gerwin, Francesco Maura, William Hooper, Minita Shah, Nicolas Robine, Philip Demarest, N. Sumru Bayin, Luz Jubierre, Casie Reed, Michael D. Taylor, Alexandra L. Joyner, G. Praveen Raju, Alex Kentsis
Genomic rearrangements are a hallmark of most solid tumors, including medulloblastoma, one of the most common brain tumors in children. Childhood cancers involve dysregulated cell development, but their mutational causes remain largely unknown. One o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5f402393cd72cef69bf54a7c55ad609
https://doi.org/10.1101/2022.07.05.498128
https://doi.org/10.1101/2022.07.05.498128
Akademický článek
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Autor:
Andrey Korshunov, Alexandra L. Joyner, Reeti Mayur Sanghrajka, Antoine Tanne, Juan J. Lafaille, N. Sumru Bayin, Raquel Duque Nascimento Arifa, Veronika Kana, Zhimin Lao, Harikrishna Rallapalli, Nina Bhardwaj, Alexandre Wojcinski, Daniel H. Turnbull, Miriam Merad, I-Li Tan
Publikováno v:
Oncogene
The immune microenvironment of tumors can play a critical role in promoting or inhibiting tumor progression depending on the context. We present evidence that tumor-associated macrophages/microglia (TAMs) can promote tumor progression in the sonic he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fb59da0407e8fb823c67896327b54a
https://doi.org/10.1038/s41388-020-01536-0
https://doi.org/10.1038/s41388-020-01536-0