Zobrazeno 1 - 10
of 82
pro vyhledávání: '"N. Seneca"'
Autor:
Phong Truong, Jan Andersson, Christer Halldin, N. Seneca, Lars Farde, David Wensbo, Patrick Raboisson
Publikováno v:
Nuclear Medicine and Biology. 40:547-553
Introduction The aims of the present positron emission tomography (PET) study were to set up a system for 11 C-cyanation labeling of the selective mGluR5-antagonist [ 11 C]AZD9272 and to perform the first in vivo characterization of [ 11 C]AZD9272 bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::772ebc63ba9bf3a1ac444408c8c1fbbf
https://doi.org/10.1016/j.nucmedbio.2012.12.012
https://doi.org/10.1016/j.nucmedbio.2012.12.012
Autor:
Anton Forsberg, Niels Andreasen, Ryuji Nakao, Stephane Nave, Per Stenkrona, Patrik Fazio, Benedicte Ricci, Candice Jamois, Christer Halldin, Zbigniew Ejduk, Andrea Varrone, Ulrika Akenine, N. Seneca, Stefan Sturm, Robert A. Comley, Nabil Al-Tawil
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Purpose In Alzheimer’s disease (AD), increased metabolism of monoamines by monoamine oxidase type B (MAO-B) leads to the production of toxic reactive oxygen species (ROS), which are thought to contribute to disease pathogenesis. Inhibition of the M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe46027f6a5b94465c0367307de9e891
https://pubmed.ncbi.nlm.nih.gov/27633250
https://pubmed.ncbi.nlm.nih.gov/27633250
Autor:
Melinda S. Merchant, N. Seneca, Lorraine Jones, Paul Lyne, Alan J. Cross, J. Mason, Janet L. Karlix, Lars Farde, Katarina Varnäs, Patricia McCoon, Manish R. Patel, Miles Congreve, Pablo Morentin Gutierrez, Jeffrey R. Infante, James D. Clarke, Ganesh Mugundu, Akihiro Takano, Peter Johnström, Gerald S. Falchook, Fiona H. Marshall, Magnus Schou
Publikováno v:
Cancer Research. 77:2641-2641
Introduction AZD4635 is an A2A receptor antagonist currently being tested as monotherapy and in combination with durvalumab in patients with advanced solid cancers. High adenosine levels found in tumors are immune suppressive and therefore AZD4635 co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::582e9299be74ee86c4a6609d6c434524
https://doi.org/10.1158/1538-7445.am2017-2641
https://doi.org/10.1158/1538-7445.am2017-2641
Autor:
Christer Halldin, Sjoerd J. Finnema, Balázs Gulyás, N. Seneca, Robert B. Innis, Håkan Wikström, Lars Farde
Publikováno v:
Synapse, 59(5), 260-269. WILEY-LISS
PET measurements of stimulant-induced dopamine (DA) release are typically performed with antagonist radioligands that bind to both the high- and low-affinity state of the receptor. In contrast, an agonist radioligand binds preferentially to the high-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d61f0291da9846647f1ec842010440
https://research.rug.nl/en/publications/8106424e-bd74-4f50-a729-4b3e391ffd2f
https://research.rug.nl/en/publications/8106424e-bd74-4f50-a729-4b3e391ffd2f
Autor:
Robert B. Innis, Magnus Schou, Bengt Andrée, Balázs Gulyás, Judit Sovago, N. Seneca, Nils Sjoholm, Stefan Pauli, Jeih-San Liow, James B. Stubbs, Christer Halldin, P. David Mozley
Publikováno v:
Nuclear medicine communications. 26(8)
(S,S)-[F]FMeNER-D2 is a recently developed norepinephrine transporter ligand which is a potentially useful radiotracer for mapping the brain and heart norepinephrine transporter in vivo using positron emission tomography. In this work, we quantified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c16dc81e2c466300cf36cb54466a2be
https://pubmed.ncbi.nlm.nih.gov/16000987
https://pubmed.ncbi.nlm.nih.gov/16000987
Autor:
N Seneca
Publikováno v:
Drugs of the Future. 36:601
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79c745721a563e4cdea38cecf4344d55
https://doi.org/10.1358/dof.2011.36.8.1633941
https://doi.org/10.1358/dof.2011.36.8.1633941
Autor:
Christer Halldin, Patrick Raboisson, Jan Andersson, Phong Truong, Donald McLeod, N. Seneca, David Wensbo, Lars Farde
Publikováno v:
NeuroImage. 52:S122
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2718a8d37eebd46906bf91bc7bd32597
https://doi.org/10.1016/j.neuroimage.2010.04.100
https://doi.org/10.1016/j.neuroimage.2010.04.100
Autor:
B. Kiss, I. Gyertyan, Margit Kapás, N. Seneca, Katalin Saghy, G. Pasztor Meszaros, E. Schmidt, G.Y. Nemeth, Z.S. Szombathelyi, István Laszlovszky, Z.S. Nemethy, Judit Laszy, G.Y. Bugovics
Publikováno v:
European Psychiatry. 23:S163
Objectives:RGH-188 is an orally active, potent dopamine D3/D2 receptor antagonist/partial agonist atypical antipsychotic for the treatment of schizophrenia and bipolar mania.Results:RGH-188 displayed high affinity to human D3 receptors (Ki: 0.085 nM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2b975e4e157c72a25cf40cf13964773
https://doi.org/10.1016/j.eurpsy.2008.01.946
https://doi.org/10.1016/j.eurpsy.2008.01.946
Autor:
Amy Medd, Lars Farde, M.E. Pierson, Jan Andersson, Mark E. Powell, Svante Nyberg, N. Seneca, C. Halldin, R. Heys, Balasz Gulyas, Dennis McCarthy, Ladislav Mrzljak, William Potts, Sjoerd J. Finnema
Publikováno v:
NeuroImage. 41:T19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a4f2cb55bd11b640eca3fcb26a0243d
https://doi.org/10.1016/j.neuroimage.2008.04.193
https://doi.org/10.1016/j.neuroimage.2008.04.193
Autor:
Christer Halldin, François Vandenhende, William Kielbasa, Andrea Varrone, Magnus Schou, Johannes Tauscher, Lars Farde, N. Seneca, Robert B. Innis, Balasz Gulyas
Publikováno v:
NeuroImage. 31:T28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eb57cdbdb4ee12a29aaa78df14c8047
https://doi.org/10.1016/j.neuroimage.2006.04.018
https://doi.org/10.1016/j.neuroimage.2006.04.018