Výsledky vyhledávání - "N. S. Melik-Nubarov"

Reversible Deactivation Radical Polymerization Mediated by Nitroxides and Green Chemistry

Autor: M. Yu. Zaremski, N. S. Melik-Nubarov

Publikováno v: Polymer Science, Series C

This review is the first attempt to consider application of some principles of green chemistry to reversible-deactivation radical polymerization mediated by nitroxides. The results of controlled synthesis of easily degradable polymers and polymers sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e81ff106a6ac70b810cd3b79a33982
https://doi.org/10.1134/s1811238221020120

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Interaction of Glutathione-Stabilized Gold Nanoclusters with Doxorubicin and Polycation

Autor: P. A. Sharanov, Victor N. Orlov, Nikolai P. Iakimov, Nikolai V. Alov, N. S. Melik-Nubarov, Va. R. Abdullina, I. D. Grozdova

Publikováno v: Russian Journal of General Chemistry. 89:2097-2102

Glutathione-capped gold nanoclusters display polyanionic properties that are manifested in the interaction with cationic species. The nanoclusters form complexes with doxorubicin with effective dissociation constant about 10 µM that increased by an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5045945f6a61ae71ef6e187e352bc59b
https://doi.org/10.1134/s1070363219100177

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Magneto-Sensitive Multiliposomal Containers for Immobilization and Controlled Delivery of Bioactive Substances

Autor: Mikhail I. Afanasov, I. G. Panova, Alexander A. Yaroslavov, V. V. Spiridonov, N. S. Melik-Nubarov, V. V. Kuznetsov, Yu. A. Alekhina, Andrey V. Sybachin

Publikováno v: Polymer Science, Series A. 61:296-307

Multiliposomal containers obtained by the successive adsorption of cationic polypeptide poly(L-lysine) and anionic liposomes on the surface of anionic magnetic microgels—the products of γ-Fe2O3 (maghemite) synthesis in the matrix of natural anioni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::621689f85afcad6820905f004912ab39
https://doi.org/10.1134/s0965545x19030167

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Biodegradable Electrostatic Complexes of Chitosan Cationic Microparticles and Anionic Liposomes

Autor: Fedor D. Mulashkin, Victor N. Orlov, Evgeniy G. Evtushenko, Galina N. Rudenskaya, A. A. Efimova, N. S. Melik-Nubarov, Alexander A. Yaroslavov, G. G. Krivtsov

Publikováno v: Polymer Science, Series B. 60:84-90

Using the electrostatic adsorption of anionic liposomes on the surface of cationic microparticles of ion-crosslinked chitosan, complexes in which each microparticle can bind up to 110 intact (undestroyed) liposomes are prepared. The saturated complex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04c30c54461e4992d23344531da0517c
https://doi.org/10.1134/s1560090418010037

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PEGylated recombinant L-asparaginase from Erwinia carotovora: Production, properties, and potential applications

Autor: G. Yu. Lomakina, S. S. Aleksandrova, O. V. Podobed, D. V. Grishin, N. S. Melik-Nubarov, I. D. Grozdova, O. Yu. Abakumova, M. V. Pokrovskaya, Nikolay N. Sokolov, V. S. Pokrovski

Publikováno v: Applied Biochemistry and Microbiology. 53:165-172

N-hydroxysuccinimide ester of monomethoxy polyethylene glycol hemisuccinate was synthesized. It acylated amino groups in a molecule of recombinant L-asparaginase from Erwinia carotovora. A method of L-asparaginase modification by the obtained activat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d8924a54c80efd41db628e81f9a5c42
https://doi.org/10.1134/s0003683817020119

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Molecular Targets of the Hydrophobic Block of Pluronics in Cells: a Photo Affinity Labelling Approach

Autor: A. E. Zhirnov, Andrey V. Romanyuk, I. D. Grozdova, Gennadii A. Badun, N. S. Melik-Nubarov, Alexander A. Ezhov, E. Nam

Publikováno v: Zhirnov, A, Nam, E, Badun, G, Romanyuk, A, Ezhov, A, Melik-Nubarov, N & Grozdova, I 2018, ' Molecular Targets of the Hydrophobic Block of Pluronics in Cells : a Photo Affinity Labelling Approach ', Pharmaceutical Research, vol. 35, no. 11, 205 . https://doi.org/10.1007/s11095-018-2484-4

Purpose: Pluronics are known as inhibitors of multidrug resistance thus making tumor cells sensitive to therapeutic doses of drugs. The purpose of our study consists in revealing molecular targets of the hydrophobic poly(propylene oxide) block of plu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8783ed9f7433465f65896696a0301104
https://pubmed.ncbi.nlm.nih.gov/30191400

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[PEGylated recombinant L-asparaginase from Erwinia carotovora: Production, properties, and potential applications]

Autor: N S, Melik-Nubarov, I D, Grozdova, G Yu, Lomakina, M V, Pokrovskaya, V S, Pokrovski, S S, Aleksandrova, O Yu, Abakumova, O V, Podobed, D V, Grishin, N N, Sokolov

Publikováno v: Prikladnaia biokhimiia i mikrobiologiia. 53(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::443b609dfcfdad27ee24fb572d2aee01
https://pubmed.ncbi.nlm.nih.gov/29508977

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Bacterial recombinant L-asparaginases: Properties, structure, and anti-proliferative activity

Autor: O. V. Podobed, Alexander I. Archakov, M. V. Pokrovskaya, N. S. Melik-Nubarov, Michael A. Eldarov, S. S. Aleksandrova, Nikolay N. Sokolov, Elena V. Kudryashova, D. V. Grishin, O. Yu. Abakumova

Publikováno v: Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 9:325-338

For more than 40 years L-asparaginases are used in combined therapy of acute lymphoblastic leukemia in children and the range of tumors sensitive to these enzymes constantly extends. This review summarizes results of studies aimed at creation of new

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b85e089aeea31667105176253c15366
https://doi.org/10.1134/s199075081504006x

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Physicochemical and biological properties of polyampholytes: Quaternized derivatives of poly(4-vinylpyridine)

Autor: E.G. Yaroslavova, N. S. Melik-Nubarov, Alexander A. Yaroslavov, T. A. Sitnikova, A. A. Rakhnyanskaya

Publikováno v: Polymer Science Series A. 55:163-170

The modification of poly(4-vinylpyridine) with ω-bromocarboxylic acids and alkyl bromides yields three types of polyampholytes: polyampholytes containing both cationic and anionic groups in each monomer unit (polybetaines), polyampholytes containing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd4bfcd8758b6701c2bfb28c881a7a0f
https://doi.org/10.1134/s0965545x13030061

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