Výsledky vyhledávání

A genome screen of maximum number of drinks as an alcoholism phenotype

Autor: N L, Saccone, J M, Kwon, J, Corbett, A, Goate, N, Rochberg, H J, Edenberg, T, Foroud, T K, Li, H, Begleiter, T, Reich, J P, Rice

Publikováno v: American journal of medical genetics. 96(5)

The Collaborative Study on the Genetics of Alcoholism (COGA) is a multicenter research program to detect and map susceptibility genes for alcohol dependence and related phenotypes. The measure M of "maximum number of drinks consumed in a 24-hour peri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fa8f62129e92156015ad56d0a22c62e5
https://pubmed.ncbi.nlm.nih.gov/11054770

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Covariates in linkage analysis

Autor: J P, Rice, N, Rochberg, R J, Neuman, N L, Saccone, K Y, Liu, X, Zhang, R, Culverhouse

Publikováno v: Genetic epidemiology. 17

We apply a novel technique to detect significant covariates in linkage analysis using a logistic regression approach. An overall test of linkage is first performed to determine whether there is significant perturbation from the expected 50% sharing u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bd2daa9d98d9e8853ccd2237ae919b7f
https://pubmed.ncbi.nlm.nih.gov/10597515

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Genome screen for platelet monoamine oxidase (MAO) activity

Autor: N L, Saccone, J P, Rice, N, Rochberg, A, Goate, T, Reich, S, Shears, W, Wu, J I, Nurnberger, T, Foroud, H J, Edenberg, T K, Li

Publikováno v: American journal of medical genetics. 88(5)

To identify loci involved in the control of platelet monoamine oxidase B (MAO-B) activity, a genomewide linkage screen was performed using 291 markers in 148 nuclear families containing a total of 1,008 nonindependent sib-pairs. Participants were gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::96dbf21cec93689bc94e81b39961b206
https://pubmed.ncbi.nlm.nih.gov/10490709

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The utility of deviant sib pairs in the detection of linkage

Autor: D R, Rochberg, N, Rochberg, C L, Hampe, B K, Suarez

Publikováno v: Genetic epidemiology. 14(6)

A tripartite sampling design was used to help deduce the genetic structure of a complex biological system. Univariate and multivariate population parameters were estimated from an age/sex stratified sample of unrelated individuals. Estimates of famil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a459934c47a9b64496e88e06fcfd88dd
https://pubmed.ncbi.nlm.nih.gov/9433593

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Schizo-affective disorders: bipolar-unipolar subtyping

Autor: P. Van Eerdewegh, N. Rochberg, M. M. Van Eerdewegh, Paula J. Clayton, J. Koepke, Jean Endicott, William Coryell

Publikováno v: Journal of Affective Disorders. 12:223-232

In view of tackling the problem of heterogeneity among the schizo-affectives, methods of univariate and multivariate statistical analysis (canonical discriminant analysis) were applied to the sociodemographic and natural history variables of four gro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::543a09d61971eea84777dbb44f837ac6
https://doi.org/10.1016/0165-0327(87)90031-0

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