Zobrazeno 1 - 10 of 104 pro vyhledávání: '"N. Ramalakshmi"'
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Akademický článek
Synthesis and Anti-inflammatory Activity of Some Novel Pyrazole Derivatives of Gallic Acid
Autor: S. Arunkumar, K. Ilango, R. S. Manikandan, N. Ramalakshmi
Publikováno v: E-Journal of Chemistry, Vol 6, Iss S1, Pp S123-S128 (2009)
In the present study, a new series of [5-substituted-3-(phenylamino)-1H-pyrazol-1yl] (3,4,5-trihydroxyphenyl)-methanone (4a-j) have been synthesized. 3, 4, 5-Trihydroxy benzohydrazide (1) was synthesized from propyl gallate and hydrazine hydrate in p
Externí odkaz: https://doaj.org/article/0eb9adbc64a8412f88e64ab9ad2cbebc
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2
COMPUTATIONAL STUDY OF Acetylcholine esterase INHIBITION BY AZAPHENOTHIAZINE ANALOGUES
Autor: null K. Premavathi, null P. Valentina, null N. Ramalakshmi
Publikováno v: RASAYAN Journal of Chemistry. 16:227-232
The present research is focused on new findings of azaphenothiazine analogs which is the promising lead moiety as the phenothiazine ring modified with azine ring as the basic nucleus reported from the literature survey that it has a wide spread of bi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6223b7b560a14478625612483153b360
https://doi.org/10.31788/rjc.2023.1616995
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4
DESIGN, SYNTHESIS, AND IN VITRO EVALUATION OF NOVEL ACRIDINE DERIVATIVES AS MONOAMINE OXIDASE INHIBITORS
Autor: R. S. Remya, null N. Ramalakshmi, C. N. Nalini, null S.Amuthalakshmi
Publikováno v: RASAYAN Journal of Chemistry. 15:2318-2325
Alzheimer's disease (AD) is a complex neurodegenerative ailment, which demands the use of multifunctional agents for its therapy. Currently, FDA-approved drugs for AD are only palliative. The current research focused on adding a flavone nucleus to th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::761af5ed1461ded96448f3d6c6206e98
https://doi.org/10.31788/rjc.2022.1547080
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5
Design Synthesis and in vitro Evaluation of Tacrine-flavone Hybrids as Multifunctional Cholinesterase Inhibitors for Alzheimer’s Disease
Autor: R. S. Remya, N. Ramalakshmi, C.N. Nalini, V. Niraimathi, S. Amuthalakshmi
Publikováno v: Current Computer-Aided Drug Design. 18:271-292
Background: Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder. The multifactorial etiology of AD has led to the design of multitarget directed ligands (MTDL) for AD. Tacrine an acetylcholinesterase (AChE) inhibitor was the fir
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::553e7d0c54b704a64d8ef09c278e4f6f
https://doi.org/10.2174/1573409918666220804153754
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6
MOLECULAR DOCKING OF NOVEL BENZOPYRAN ANALOGUES AND INHIBITION PROPERTIES OF ANTIDIABETIC AGENTS AGAINST α-AMYLASE AND αGLUCOSIDASE
Autor: null D.Bharathi, null P. Valentina, null N. Ramalakshmi
Publikováno v: RASAYAN Journal of Chemistry. 15:2873-2878
Alpha amylase and alpha-glucosidase inhibitors play a key role in treating diabetes mellitus. Based on this idea the present study aimed in designing different benzopyran analogs and investigate the binding interaction with protein PDB: 1HNY and PDB:
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c0dd45e7bcca8668a275aedb213ab2c
https://doi.org/10.31788/rjc.2022.1547075
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