Zobrazeno 1 - 10 of 184 pro vyhledávání: '"N. R. Stokes"'
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Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 1
Autor: A. Ratcliffe, A. Smith, A-M. Salisbury, C. Charrier, N. R. Stokes, P. Schofield, G. Noonan, J. Cheung, E. Moyo, M. Uosis-Martin, S. Mohmed, J. Massam, M. Craighead, R. Metzger, A. Huxley, O. Bardell-Cox, D. R. Jones, R. Armer, S. Hindley, J. Maclean, N. Chalam-Judge, V. Savage, R. Kirk, S. Best, D. Lyth
Publikováno v: RSC Med Chem
The alarming reduction in drug effectiveness against bacterial infections has created an urgent need for the development of new antibacterial agents that circumvent bacterial resistance mechanisms. We report here a series of DNA gyrase and topoisomer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e555943ef527fbbe3d583623ccd140a
https://doi.org/10.1039/d0md00174k
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2
Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 2
Autor: N. R. Stokes, C. Charrier, V. Savage, R. Armer, N. Ooi, A. Ratcliffe, O. Bardell-Cox, E. Moyo, G. Noonan, J. Cheung, A. Huxley, A. Smith, D. Clare, A-M. Salisbury, J. Massam, J. Maclean, N. Chalam-Judge, M. Craighead, S. Mohmed, S. Best, R. Kirk, A. Lyons, D. Lyth, M. Uosis-Martin, P. Schofield
Publikováno v: RSC Med Chem
Building on our previously-reported novel tricyclic topoisomerase inhibitors (NTTIs), we disclose the discovery of REDX07965, which has an MIC(90) of 0.5 μg mL(−1) against Staphylococcus aureus, favourable in vitro pharmacokinetic properties, sele
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbabb6bae25b15c2e77273e6b19a0a08
https://pubmed.ncbi.nlm.nih.gov/34095845
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3
Akademický článek
Terpene-Functionalized Fluoroquinolones as Potential Antimicrobials: Synthesis and Properties.
Autor: Izmest'ev ES; Institute of Chemistry, FRC Komi Science Center Ural Branch of the Russian Academy of Sciences, 48, Pervomaiskaya St., 167000, Syktyvkar, Russian Federation., Pestova SV; Institute of Chemistry, FRC Komi Science Center Ural Branch of the Russian Academy of Sciences, 48, Pervomaiskaya St., 167000, Syktyvkar, Russian Federation., Kolesnikova AI; Institute of Fundamental Medicine and Biology, Kazan Federal University, 18, Kremlevskaya St., 420008, Kazan, Russian Federation., Baidamshina DR; Institute of Fundamental Medicine and Biology, Kazan Federal University, 18, Kremlevskaya St., 420008, Kazan, Russian Federation., Kayumov AR; Institute of Fundamental Medicine and Biology, Kazan Federal University, 18, Kremlevskaya St., 420008, Kazan, Russian Federation., Rubtsova SA; Institute of Chemistry, FRC Komi Science Center Ural Branch of the Russian Academy of Sciences, 48, Pervomaiskaya St., 167000, Syktyvkar, Russian Federation.
Publikováno v: ChemMedChem [ChemMedChem] 2023 Dec 14; Vol. 18 (24), pp. e202300358. Date of Electronic Publication: 2023 Nov 10.
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5
The Occultation of BD -17° 4388 by Neptune: II. Photo-electric observations
Autor: Kenneth C. Freeman, G. LyngÅ, M. J. Miller, K. Serkowski, N. R. Stokes
Publikováno v: Publications of the Astronomical Society of Australia. 1:201-203
Photo-electric observations of the occultation of BD —17°4388 by Neptune on 1968 April 7 were made with instruments and techniques as listed in Table I. A preliminary report of these observations has been given in IAU Circular No. 2067.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fb97e17c9943462069eef7a3af53c13
https://doi.org/10.1017/s1323358000011474
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6
Akademický článek
Simulating the Transport and Rupture of Pollen in the Atmosphere.
Autor: Subba, Tamanna1,2 (AUTHOR) tsubba@umich.edu, Zhang, Yingxiao1 (AUTHOR), Steiner, Allison L.1 (AUTHOR)
Publikováno v: Journal of Advances in Modeling Earth Systems. Mar2023, Vol. 15 Issue 3, p1-25. 25p.
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7
Akademický článek
Effect of monolayer spontaneous curvature on constant tension-induced pore formation in lipid bilayers.
Autor: Tazawa, Kanta, Yamazaki, Masahito
Publikováno v: Journal of Chemical Physics; 2/28/2023, Vol. 158 Issue 8, p1-7, 7p
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8
Akademický článek
Dynamic Interactions Between Brilliant Green and MscL Investigated by Solid‐State NMR Spectroscopy and Molecular Dynamics Simulations.
Autor: Ma, Shaojie1,2,3 (AUTHOR), Zhang, Yan1,4 (AUTHOR), Zhang, Xuning1,3 (AUTHOR), Xie, Huayong1 (AUTHOR), Tong, Qiong1 (AUTHOR) tongqiong@wipm.ac.cn, Yu, Kunqian2 (AUTHOR) yukunqian@simm.ac.cn, Yang, Jun1,3,4,5 (AUTHOR) yangjun@wipm.ac.cn
Publikováno v: Chemistry - A European Journal. Jan2023, Vol. 29 Issue 3, p1-11. 11p.
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9
Akademický článek
Efficient Synthesis of 4‐Bromo‐N‐(1‐phenylethyl)benzamide, Arylation by Pd(0) Catalyst, Characterization and DFT Study.
Autor: Raza Shah, Alı1 (AUTHOR), Rasool, Nasır1 (AUTHOR) nasirrasool@gcuf.edu.pk, Bılal, Muhammad1 (AUTHOR), Mubarık, Adeel1 (AUTHOR), Alı Hashmı, Muhammad2 (AUTHOR), Nadeem Akhtar, Muhammad3 (AUTHOR), Imran, Muhammad4,5 (AUTHOR) imranchemist@gmail.com, Ahmad, Gulraız1 (AUTHOR), Siddiqa, Ayesha1 (AUTHOR), Adnan Alı Shah, Syed6,7 (AUTHOR)
Publikováno v: ChemistrySelect. 8/5/2022, Vol. 7 Issue 29, p1-9. 9p.
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