Zobrazeno 1 - 10
of 60
pro vyhledávání: '"N. R. Morris"'
Autor:
G. C. M. Bruschi, N. R. Morris, C. C. de Souza, M. A C Dani, Marcia Regina von Zeska Kress Fagundes, Gustavo H. Goldman, Maria Helena S. Goldman, Leroy-Fong Liu
Publikováno v:
Molecular Genetics and Genomics. 265:264-275
The anti-cancer drug camptothecin targets eukaryotic DNA topoisomerase I by trapping the covalent complex formed between the catalytically active enzyme and DNA. We are interested in identifying factors, other than topoisomerase I, that are involved
Publikováno v:
Current Genetics. 35:626-630
In the filamentous fungus Aspergillus nidulans, nuclear migration in the germ tube is mediated by cytoplasmic dynein. We have previously reported the characterization of four nud (nuclear distribution) genes, nudA, nudC, nudF and nudG, involved in th
Autor:
V P Efimov, N R Morris
Publikováno v:
Genetics. 149:101-116
Cytoplasmic dynein is a ubiquitously expressed microtubule motor involved in vesicle transport, mitosis, nuclear migration, and spindle orientation. In the filamentous fungus Aspergillus nidulans, inactivation of cytoplasmic dynein, although not leth
Publikováno v:
Molecular Biology of the Cell. 8:1735-1749
Nuclear migration is required for normal development in both higher and lower eukaryotes. In fungi this process is mediated by cytoplasmic dynein. It is believed that this motor protein is anchored to the cell membrane and moves nuclei by capturing a
Autor:
N R Morris, Ya-Hui Chiu
Publikováno v:
Genetics. 145:707-714
NudC encodes a protein of unknown biochemical function that is required for nuclear migration. In an attempt to define its function by identifying interacting proteins, a screen for extragenic suppressors of the temperature-sensitive nudC3 mutation w
Publikováno v:
Genetics. 141:1287-1298
Microtubules and cytoplasmic dynein, a microtubule-dependent motor, are required for nuclei to move along the hyphae of filamentous fungi. Nuclear migration in Aspergillus nidulans is blocked by heat-sensitive (hs-) mutations in the nudA gene, which
Publikováno v:
Journal of Cell Science. 108:3485-3499
The bimE (blocked-in-mitosis) gene appears to function as a negative mitotic regulator because the recessive bimE7 mutation can override certain interphase-arresting treatments and mutations, causing abnormal induction of mitosis. We have further inv
Autor:
K E, Kirk, N R, Morris
Publikováno v:
Molecular and Cellular Biology. 13:4465-4476
The filamentous fungus Aspergillus nidulans has two genes encoding alpha-tubulin, tubA and tubB, which are differentially required at distinct stages during the life cycle. The tubA gene is required during vegetative growth for mitosis and nuclear mi
Autor:
K E Kirk, N R Morris
Publikováno v:
Molecular and Cellular Biology. 13:4465-4476
The filamentous fungus Aspergillus nidulans has two genes encoding alpha-tubulin, tubA and tubB, which are differentially required at distinct stages during the life cycle. The tubA gene is required during vegetative growth for mitosis and nuclear mi
Publikováno v:
The Journal of Cell Biology
To investigate the relationship between structure and function of kinesin-like proteins, we have identified by polymerase chain reaction (PCR) a new kinesin-like protein in the filamentous fungus Aspergillus nidulans, which we have designated KLPA. D