Zobrazeno 1 - 10 of 14 pro vyhledávání: '"N. R. Labiris"'
1
Pulmonary drug delivery. Part II: The role of inhalant delivery devices and drug formulations in therapeutic effectiveness of aerosolized medications
Autor: N. R. Labiris, Myrna Dolovich
Publikováno v: British Journal of Clinical Pharmacology. 56:600-612
Research in the area of pulmonary drug delivery has gathered momentum in the last several years, with increased interest in using the lung as a means of delivering drugs systemically. Advances in device technology have led to the development of more
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d8f7e95b08f89dcd3b23c69612be16b
https://doi.org/10.1046/j.1365-2125.2003.01893.x
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2
Pulmonary drug delivery. Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications
Autor: N. R. Labiris, Myrna Dolovich
Publikováno v: British Journal of Clinical Pharmacology. 56:588-599
As the end organ for the treatment of local diseases or as the route of administration for systemic therapies, the lung is a very attractive target for drug delivery. It provides direct access to disease in the treatment of respiratory diseases, whil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e6bbe9ec4552816ee90b0881eda5c0ed
https://doi.org/10.1046/j.1365-2125.2003.01892.x
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3
Persistence of pulmonary tertiary lymphoid tissues and anti-nuclear antibodies following cessation of cigarette smoke exposure
Autor: Martin R. Stämpfli, Danya Thayaparan, Pamela Shen, Jake K. Nikota, N R. Labiris, Alison A. Humbles, Parameswaran Nair, Mathieu C. Morissette, Roland Kolbeck, Brian N. Jobse
Publikováno v: Respiratory Research
Formation of pulmonary tertiary immune structures is a characteristic feature of advanced COPD. In the current study, we investigated the mechanisms of tertiary lymphoid tissue (TLT) formation in the lungs of cigarette smoke-exposed mice. We found th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5b9d9dfe959090cf7b9ec1fc7a0ba6
https://doi.org/10.1186/1465-9921-15-49
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4
Impact of inflammation, emphysema, and smoking cessation on V/Q in mouse models of lung obstruction
Autor: N R. Labiris, Brian N. Jobse, Cory A. J. R. McCurry, Martin R. Stämpfli, Mathieu C. Morissette, Rod G. Rhem
Publikováno v: Respiratory Research
Background Chronic obstructive pulmonary disease (COPD) is known to greatly affect ventilation (V) and perfusion (Q) of the lung through pathologies such as inflammation and emphysema. However, there is little direct evidence regarding how these path
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5de8c51c01b2b89066db0746b4c7852
https://doi.org/10.1186/1465-9921-15-42
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5
Airway and pulmonary vascular measurements using contrast-enhanced micro-CT in rodents
Autor: Iris Q. Wang, N. R. Labiris, Troy Farncombe, William B. Counter
Publikováno v: American journal of physiology. Lung cellular and molecular physiology. 304(12)
Preclinical imaging allows pulmonary researchers to study lung disease and pulmonary drug delivery noninvasively and longitudinally in small animals. However, anatomically localizing a pathology or drug deposition to a particular lung region is not e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2138c1061e7a18a35f35ad976cddac78
https://pubmed.ncbi.nlm.nih.gov/23564512
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10
The effects of inhaled house dust mite on airway barrier function and sensitivity to inhaled methacholine in mice
Autor: G. J. Turi, Jennifer Wattie, N. R. Labiris, Mark D. Inman, Russ Ellis
Publikováno v: American journal of physiology. Lung cellular and molecular physiology. 300(2)
Asthma is functionally characterized by increased airway sensitivity and reactivity. Multiple mechanisms are believed to underlie these functional disorders, including impairment of airway wall barrier function. One proposed mechanism of impaired bar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f986180c8456f1f5401530e658f9bc88
https://pubmed.ncbi.nlm.nih.gov/21056959
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