Zobrazeno 1 - 10
of 20
pro vyhledávání: '"N. R. Battulin"'
Autor:
A. M. Yunusova, A. V. Smirnov, T. A. Shnaider, I. E. Pristyazhnuk, S. Y. Korableva, N. R. Battulin
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 28, Iss 5, Pp 487-494 (2024)
Chromatin is not randomly distributed within the nucleus, but organized in a three-dimensional structure that plays a critical role in genome functions. Сohesin and condensins are conserved multi-subunit protein complexes that participate in mammali
Externí odkaz:
https://doaj.org/article/e79b03123ed844f8a7f415e53718885c
Autor:
A. M. Yunusova, A. V. Smirnov, I. E. Pristyazhnuk, T. A. Shnaider, E. K. Maltseva, S. D. Afonnikova, O. A. Gusev, N. R. Battulin
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 28, Iss 2, Pp 138-147 (2024)
One of the most productive strategies for finding the functions of proteins is to study the consequences of loss of protein function. For this purpose, cells or organisms with a knockout of the gene encoding the protein of interest are obtained. Howe
Externí odkaz:
https://doaj.org/article/51c110c75d4b4411afee0e400636d258
Autor:
N. R. Battulin, O. L. Serov
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 26, Iss 4, Pp 402-408 (2022)
Over the past 20 years, coronaviruses have caused three epidemics: SARS-CoV, MERS-CoV, and SARS-CoV2, with the first two having a very high lethality of about 10 and 26 %, respectively. The last outbreak of coronavirus infection caused by SARS-CoV2 i
Externí odkaz:
https://doaj.org/article/8091b1fc73f044948dcf74ab142e020b
Autor:
A. V. Smirnov, G. V. Kontsevaya, T. A. Shnaider, A. M. Yunusova, N. A. Feofanova, L. A. Gerlinskaya, I. A. Serova, O. L. Serov, N. R. Battulin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Transgenic animals are an important tool in biotechnology, including the production of recombinant proteins in the milk. Traditionally, expression constructs are based on hybrid vectors bearing mammary gland specific regulatory elements from
Externí odkaz:
https://doaj.org/article/902604134ebe42d6ba600999d76fa66c
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 25, Iss 3, Pp 331-336 (2021)
Caseins are major milk proteins that have an evolutionarily conserved role in nutrition. Sequence variations in the casein genes affect milk composition in livestock species. Regulatory elements of the casein genes could be used to direct the express
Externí odkaz:
https://doaj.org/article/3b879f8529834efea99c0394821d4e55
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 23, Iss 1, Pp 95-99 (2019)
A totipotent zygote has unlimited potential for differentiation into all cell types found in an adult organism. During ontogenesis proliferating and maturing cells gradually lose their differentiation potential, limiting the spectrum of possible deve
Externí odkaz:
https://doaj.org/article/453d53709e524ee3b2ede2e0b7d4f4fe
Autor:
A. M. Yunusova, N. R. Battulin
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 20, Iss 6, Pp 909-917 (2017)
A zygote, the only totipotent cell of the developing organism, transforms into a complex, multicellular entity with billions (for humans) of highly specialized cells and tissues. Most adult tissues are maintained by a combination of highly dynamic pr
Externí odkaz:
https://doaj.org/article/18d01d986ddb43818a09835a4188784e
Autor:
A. V. Smirnov, N. A. Feofanova, G. V. Kontsevaya, M. V. Anisimova, I. I. Kovrigin, I. A. Serova, M. P. Moshkin, L. A. Gerlinskaya, N. R. Battulin
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 20, Iss 6, Pp 918-924 (2017)
Transgenesis has become a routine for modern biological studies. The most popular method for producing transgenic animals–pronuclear microinjection–frequently leads to host gene disruption due to a random transgene integration. In this paper, we
Externí odkaz:
https://doaj.org/article/53836fff584c460e999babf9abbd5d32
Autor:
G. V. Kontsevaya, N. A. Feofanova, A. G. Menzorov, I. E. Pristyazhnyuk, A. V. Smirnov, N. R. Battulin, L. A. Gerlinskaya
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 20, Iss 6, Pp 925-929 (2017)
Embryonic stem cells are commonly used for generation of transgenic mice. Embryonic stem cells could participate in the development of chimeric animals after injection into a blastocyst. Injection of genetically modified embryonic stem cells could le
Externí odkaz:
https://doaj.org/article/5f348632f0fb431e888adeffbd3d7e72
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 20, Iss 4, Pp 493-510 (2016)
The CRISPR/Cas9 system was initially described as an element of archeal and bacterial immunity, but gained much attention recently for its outstanding ability to be programmed to target any genomic loci through a short 20-nucleotide sgRNA region. Her
Externí odkaz:
https://doaj.org/article/ad278f5b724d44e994395ea29e1f5068