Zobrazeno 1 - 10
of 329
pro vyhledávání: '"N. Parkinson"'
Autor:
Dilek Guneri, Effrosyni Alexandrou, Kamel El Omari, Zuzana Dvořáková, Rupesh V. Chikhale, Daniel T. S. Pike, Christopher A. Waudby, Christopher J. Morris, Shozeb Haider, Gary N. Parkinson, Zoë A. E. Waller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The insulin-linked polymorphic region is a variable number of tandem repeats region of DNA in the promoter of the insulin gene that regulates transcription of insulin. This region is known to form the alternative DNA structures, i-motifs and
Externí odkaz:
https://doaj.org/article/f3133e77e6154bdd947d113634a42cc4
Autor:
Cassandra L Stowe, Thomas A Burley, Helen Allan, Maria Vinci, Gabriela Kramer-Marek, Daniela M Ciobota, Gary N Parkinson, Tara L Southworth, Giulia Agliardi, Alastair Hotblack, Mark F Lythgoe, Bruce R Branchini, Tammy L Kalber, James C Anderson, Martin A Pule
Publikováno v:
eLife, Vol 8 (2019)
Bioluminescence imaging (BLI) is ubiquitous in scientific research for the sensitive tracking of biological processes in small animal models. However, due to the attenuation of visible light by tissue, and the limited set of near-infrared bioluminesc
Externí odkaz:
https://doaj.org/article/28633a3c3ec14220bcd7ff7a3ce49ce3
Akademický článek
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Publikováno v:
Journal of Nucleic Acids, Vol 2018 (2018)
Externí odkaz:
https://doaj.org/article/7fab370a99ff4a2ca3a9b037566131b8
Autor:
Suzana Almoosawi, Angela R Jones, Kathryn N Parkinson, Mark S Pearce, Heather Collins, Ashley J Adamson
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0144931 (2016)
OBJECTIVE:Recognising overweight and obesity is critical to prompting action, and consequently preventing and treating obesity. The present study examined the association between parental perceptions of child weight status and child's diet. METHODS:P
Externí odkaz:
https://doaj.org/article/5f859d36d7b444cca67772ff3c5cce3f
Autor:
Gary N. Parkinson, Hany I. Mohamed, Song Zibing, Chao Gao, Zhu Liu, Dengguo Wei, Mingqian Feng, Zhe Hu, Jieqin Ding, Haitao Hou, Shengzhen Xu, Shozeb Haider, Congbao Xie, Xin Chen
Publikováno v:
Nucleic Acids Research
A single G-quadruplex forming sequence from the human telomere can adopt six distinct topologies that are inter-convertible under physiological conditions. This presents challenges to design ligands that show selectivity and specificity towards a par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2567b309f656b634a3a9f673b6ae9a8
https://doi.org/10.1093/nar/gkaa870
https://doi.org/10.1093/nar/gkaa870
Autor:
Yashu Zhang, Kamel El Omari, Armin Wagner, Dengguo Wei, Gary N. Parkinson, Ramona Duman, Shozeb Haider, Sisi Liu
Publikováno v:
Nucleic Acids Research
Obtaining phase information remains a formidable challenge for nucleic acid structure determination. The introduction of an X-ray synchrotron beamline designed to be tunable to long wavelengths at Diamond Light Source has opened the possibility to na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621ae2b6906798002f6d6a776cdb000b
https://doi.org/10.1093/nar/gkaa439
https://doi.org/10.1093/nar/gkaa439
Autor:
Kay D. Mann, Laura Basterfield, Ashley J. Adamson, John J. Reilly, Gateshead Millennium Study core team, Kathryn N. Parkinson, Charlotte M Wright, Mark S. Pearce, Jessica K. Reilly
Publikováno v:
Journal of Developmental Origins of Health and Disease. 10:621-626
Birth weight and early growth have been associated with later blood pressure. However, not all studies consistently find a significant reduction in blood pressure with an increase in birth weight. In addition, the relative importance of birth weight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac07261114603beccd330f4e59121b0a
https://doi.org/10.1017/s2040174418001095
https://doi.org/10.1017/s2040174418001095
Autor:
Gary N, Parkinson, Helen, Berman
Publikováno v:
Bioorganic & Medicinal Chemistry. 69:116887
As scientists who have worked with Stephen Neidle over many years and stages of his career, we present our perspective of his contributions to nucleic acid structural science. We trace some of the highlights of his research on nucleic acid drug inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9d799f8e4bb43f4994dc198b47202b
https://doi.org/10.1016/j.bmc.2022.116887
https://doi.org/10.1016/j.bmc.2022.116887
Autor:
Dejan-Krešimir Bučar, Asma B. M. Buanz, Dongpeng Yan, Gareth R. Williams, Alexander E. Clout, Timothy J. Prior, Gary N. Parkinson, Yuying Pang, Simon Gaisford, Wing‐Mei Tsui
Publikováno v:
Clout, A 2020, ' Mechanistic in situ and ex situ studies of phase transformations in molecular co-crystals ', Chemistry – A European Journal . https://doi.org/10.1002/chem.202002267
Chemistry (Weinheim an Der Bergstrasse, Germany)
Chemistry (Weinheim an Der Bergstrasse, Germany)
Co‐crystallisation is widely explored as a route to improve the physical properties of pharmaceutical active ingredients, but little is known about the fundamental mechanisms of the process. Herein, we apply a hyphenated differential scanning calor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4591f6d65471dc3b719b28f800bd827a
https://www.research.manchester.ac.uk/portal/en/publications/mechanistic-in-situ-and-ex-situ-studies-of-phase-transformations-in-molecular-cocrystals(7e837bf2-ff92-4cd3-842d-11b39543e25d).html
https://www.research.manchester.ac.uk/portal/en/publications/mechanistic-in-situ-and-ex-situ-studies-of-phase-transformations-in-molecular-cocrystals(7e837bf2-ff92-4cd3-842d-11b39543e25d).html
