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Akademický článek

Markers of chronic low-grade inflammation and serum cytokine levels in patients with type 1 diabetes: associations with time in ranges and glucose variability

Autor: K. R. Mavlianova, Ju. F. Semenova, N. B. Orlov, V. V. Klimontov

Publikováno v: Сахарный диабет, Vol 27, Iss 3, Pp 214-223 (2024)

BACKGROUND: Increased glucose variability is recognized as a risk factor for vascular diabetic complications. It is assumed that deteriorating effect of GV on blood vessels can be realized through the activation of inflammatory signaling pathways.AIM

Externí odkaz: https://doaj.org/article/110fcc2539d14c378228bfdac332200a

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Akademický článek

Association of polymorphic variants of cytokines genes, endothelial growth factor and matrix metalloproteinases with the development of uterine fibroids among russian women

Autor: Е. G. Koroleva, V. I. Konenkov, A. V. Shevchenko, V. F. Prokofiev, N. В. Orlov, Yu. S. Timofeeva, S. V. Aidagulova, I. О. Marinkin

Publikováno v: Сибирский научный медицинский журнал, Vol 44, Iss 2, Pp 113-122 (2024)

One of the factors in the development of uterine fibroids is a genetic predisposition to its occurrence in some women, but the real molecular genetic mechanisms of this phenomenon remain unknown. Aim of the study was the distribution analysis of gene

Externí odkaz: https://doaj.org/article/3837dccf7c9843ea967910b77f022eee

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Akademický článek

Features of the level of matrix metalloproteinase-2, -3, -9 and tissue inhibitors of metalloproteinases-1, -2, -3, -4 in the aqueous humor of patients with primary open-angle glaucoma

Autor: V. V. Chernykh, V. I. Konenkov, O. V. Ermakova, N. B. Orlov, A. N. Trunov

Publikováno v: Бюллетень сибирской медицины, Vol 20, Iss 4, Pp 86-92 (2022)

Aim. To study the content of matrix metalloproteinase (MMP)-2, -3, -9 and tissue inhibitors of metalloproteinases (TIMPs) -1, -2, -3, -4 in the aqueous humor of patients with moderate primary open-angle glaucoma (POAG).Materials and methods. The expe

Externí odkaz: https://doaj.org/article/b84c7c6a83f64a34a4a1085d9fe04009

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Akademický článek

Content of matrix metalloproteinases in the intraocular fluid of patients with primary open-angle glaucoma

Autor: V. V. Chernykh, V. I. Konenkov, O. V. Ermakova, N. B. Orlov, А. N. Trunov

Publikováno v: Сибирский научный медицинский журнал, Vol 40, Iss 5, Pp 73-78 (2020)

Aim of the study was to investigate the content of matrix metalloproteinases 2, 3, 9, in the intraocular fluid of patients with a developed stage of primary open-angle glaucoma. Material and methods. The study included 47 patients with advanced stage

Externí odkaz: https://doaj.org/article/bc9d9765fef949119dfb2818c206721c

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Akademický článek

CORRELATION BETWEEN CYTOKINE CONTENT IN LYMPH OF THORACIC LYMPH DUCT AND MESENTERIC LYMPH NODE STRUCTURAL TRANSFORMATIONS IN EXPERIMENTAL MAMMARY TUMOR AND CHEMOTHERAPY

Autor: O. V. Kazakov, T. V. Rayter, A. F. Poveshchenko, N. B. Orlov, O. V. Poveshchenko, A. V. Kabakov, A. P. Lykov, I. I. Kim, N. A. Bondarenko, D. N. Strunkin, V. I. Konenkov

Publikováno v: Сибирский научный медицинский журнал, Vol 39, Iss 5, Pp 84-91 (2019)

The aim of the study was to fulfill correlation analysis of morphometry of the mesenteric lymph nodes and the concentration of cytokines in the lymph of the thoracic duct in breast cancer induced by intramammary administration of N-methyl-N-nitrosour

Externí odkaz: https://doaj.org/article/9e155aad580c47b29a10dc3fcbf32fed

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Akademický článek

Ghrelin deficiency in patients with type 2 diabetes: the relationships with obesity, adipose tissue dysfunction and glucose variability

Autor: V V Klimontov, D M Bulumbaeva, O N Fazullina, N B Orlov, V I Konenkov

Publikováno v: Терапевтический архив, Vol 91, Iss 10, Pp 28-33 (2019)

Aim. Ghrelin, a peptide hormone mostly produced by stomach, plays an important role in regulation of feeding behavior, energy balance and glucose homeostasis. The aim: to determine the relationships between fasting serum levels of ghrelin, body compo

Externí odkaz: https://doaj.org/article/0e5fc151be284563b5860cda22083ce9

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Akademický článek

Features of the content of transforming growth factors – beta 1,2,3 (TGF-β1, TGF-β2, TGF-β3) in intraocular fluid in primary open-angle glaucoma

Autor: V. V. Chernykh, V. I. Konenkov, N. B. Orlov, O. V. Ermakova, N. S. Khodzhaev, A. N. Trunov

Publikováno v: Офтальмохирургия, Vol 0, Iss 2, Pp 13-17 (2019)

Purpose. To study transforming growth factors – beta 1,2,3 (TGF-β1, TGF-β2, TGF-β3) in intraocular aqueous humor (AH) of patients with the advanced stage of primary open angle glaucoma (POAG).Material and methods. The study included an examinati

Externí odkaz: https://doaj.org/article/5f3a83ff26614a418af3b39ee31734f5

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Akademický článek

Сontent of cytokines and growth factors in the intraocular fluid of patients with primary open-angle glaucoma

Autor: V. V. Chernykh, V. I. Konenkov, O. V. Ermakova, N. B. Orlov, O. O. Obukhova, A. V. Eremina, A. N. Trunov

Publikováno v: Бюллетень сибирской медицины, Vol 18, Iss 1, Pp 257-265 (2019)

Purpose. To study the content of cytokines and growth factors in the intraocular fluid of patients with developed stage of primary open-angle glaucoma (POAG).Materials and methods. 56 patients with a verified diagnosis developed stage of primary open

Externí odkaz: https://doaj.org/article/a53f083538f3441481103ac97fc899f9

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Akademický článek

FEATURES OF THE CONTENT OF PROINFLAMMATORY CYTOKINES IN LACRIMAL AND INTRAOCULAR FLUID IN PATIENTS WITH PRIMARY OPEN-ANGLE GLAUCOMA

Autor: V. V. Chernykh, O. V. Ermakova, N. B. Orlov, O. O. Obukhova, O. M. Gorbenko, A. P. Shvayuk, A. V. Eremina, A. N. Trunov

Publikováno v: Сибирский научный медицинский журнал, Vol 38, Iss 5, Pp 5-10 (2019)

Purpose: to study the content of proinflammatory cytokines IL-6, IL-8 and IL-17 in lacrimal and intraocular fluid in patients with advanced stage of primary open-angle glaucoma. Material and methods. The study included 56 patients with advanced stage

Externí odkaz: https://doaj.org/article/d25f813b49544c76b9974ab387328656

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