Výsledky vyhledávání - "N. P. D. Nanayakkara"

Isolation and characterization of 2-pyridone alkaloids and alloxazines from Beauveria bassiana

Autor: W. J. Andrioli, A. A. Lopes, B. C. Cavalcanti, C. Pessoa, N. P. D. Nanayakkara, J. K. Bastos

Two novel compounds bearing heterocyclic nitrogen, 2-pyridone alkaloid (1) and alloxazine derivative (2), along with the known pretenellin B (3), pyridovericin (4) and lumichrome (5) were isolated from a culture of the entomopathogenic fungal strain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd8a75a806989125327c0f60ac8156e

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GC-MS Analysis of the 8-Aminoquinoline Antimalarial [NPC1161] and its Carboxy Metabolite in Plasma and Red Blood Cells of Primates

Autor: Waseem Gul, N. P. D. Nanayakkara, Alice M. Clark, S. Feng, Larry A. Walker, Shabana I. Khan, F. B. Cogswell, Mahmoud A. ElSohly

Publikováno v: Chromatographia. 64:199-205

This study describes a novel and simple GC-MS procedure developed for the determination of the concentration of the 8-aminoquinoline antimalarial agent NPC1161 and its carboxy metabolite in plasma and red blood cells. Preliminary pharmacokinetic data

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94041c26a312eba5b6e2fb55d80511f5
https://doi.org/10.1365/s10337-006-0015-7

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Determination of saponins and alkaloids inCaulophyllum thalictroides (blue cohosh) by high-performance liquid chromatography and evaporative light scattering detection

Autor: Markus Ganzera, H. R. W. Dharmaratne, Ikhlas A. Khan, N. P. D. Nanayakkara

Publikováno v: Phytochemical Analysis. 14:1-7

The roots of Caulophyllum thalictroides, traditionally used for the treatment of menstrual difficulties and as an aid in childbirth, contain saponins, which are considered to be responsible for the uterine stimulant effects, together with teratogenic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980643531dfc4cff624f19064ded7cb7
https://doi.org/10.1002/pca.666

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Mass spectral analysis of some derivatives andin vitro metabolites of steviol, the aglycone of the natural sweeteners, stevioside, rebaudioside a, and rubusoside

Autor: Cesar M. Compadre, A. D. Kinghorn, John M. Pezzuto, N. P. D. Nanayakkara, Raouf A. Hussain

Publikováno v: Biological Mass Spectrometry. 15:211-222

Steviol (ent-13-hydroxykaur-16-en-19-oic acid), the aglycone of various plant-derived glycoside sweeteners consumed by human populations, is known to be mutagenic toward Salmonella tymphimurium strain TM677 when metabolically activated using a 9000 x

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5327e4240482baa26c3fceb9062e8b45
https://doi.org/10.1002/bms.1200150405

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A phytochemical screening procedure for sweet ent-kaurene glycosides in the genus Stevia

Autor: Djaja D. Soejarto, Cesar M. Compadre, P. J. Medon, S. K. Kamath, A. D. Kinghorn, N. P. D. Nanayakkara, Helena C. Makapugay, J. M. Hovanec-Brown

Publikováno v: Journal of natural products. 47(3)

Altogether, 110 species of the genus Stevia, comprising both herbarium and fresh leaf samples, were screened for the presence of sweet ent-kaurene glycosides, using a combination of tlc and hplc, followed by gc/ms. Stevioside and rebaudiosides A and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697ceb150ecc2f76497b56a163769b45
https://pubmed.ncbi.nlm.nih.gov/6481357

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Characterization and feeding deterrent effects on the aphid, Schizaphis graminum, of some derivatives of the sweet compounds, stevioside and rebaudioside A

Autor: J. A. Klocke, A. D. Kinghorn, Cesar M. Compadre, Raouf A. Hussain, John M. Pezzuto, N. P. D. Nanayakkara

Publikováno v: Journal of natural products. 50(3)

The intensely sweet compounds, stevioside [1] and rebaudioside A [2], and 15 of their derivatives, were tested for feeding deterrent activity against the aphid, Schizaphis graminum. Included with these compounds was steviol [4], the aglycone of stevi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429b0ec3e909c08dba6e4a2c1519b467
https://pubmed.ncbi.nlm.nih.gov/3668559

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Plant Anticancer Agents XXXVII. Constituents ofAmanoa oblongifolia

Autor: Norman R. Farnsworth, Charles H. Phoebe, A. D. Kinghorn, Xinde Fang, N. P. D. Nanayakkara, John M. Pezzuto

Publikováno v: Planta Medica. 51:346-347

4'-Demethyldeoxypodophyllotoxin was isolated as the sole cytotoxic constituent of a chloroform-soluble extract of the stem bark of AMANOA OBLONGIFOLIA. Also identified from this extract were a number of noncytotoxic isolates that comprised the lignan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a576f6b63c65a8dae3721133d1c09b5f
https://doi.org/10.1055/s-2007-969511

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