Zobrazeno 1 - 10
of 31
pro vyhledávání: '"N. P. Bailey"'
Autor:
Wendy W. Liu, Tyler G. Kinzy, Jessica N. Cooke Bailey, Zihe Xu, Pirro Hysi, Janey L. Wiggs, NEIGHBORHOOD Consortium
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Although glaucoma is a disease modulated by eye pressure, the mechanisms of pressure sensing in the eye are not well understood. Here, we investigated associations between mechanosensitive ion channel gene variants and primary open-angle gla
Externí odkaz:
https://doaj.org/article/71e99a7591124c8bbe41fc3b922d5713
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract A series of gallium arsenide bismide device layers covering a range of growth conditions are thoroughly probed by low-temperature, power-dependent photoluminescence measurements. The photoluminescence data is modelled using a localised state
Externí odkaz:
https://doaj.org/article/917286504a3e4248a838c9b0747cef65
Autor:
Puya Gharahkhani, Eric Jorgenson, Pirro Hysi, Anthony P. Khawaja, Sarah Pendergrass, Xikun Han, Jue Sheng Ong, Alex W. Hewitt, Ayellet V. Segrè, John M. Rouhana, Andrew R. Hamel, Robert P. Igo, Helene Choquet, Ayub Qassim, Navya S. Josyula, Jessica N. Cooke Bailey, Pieter W. M. Bonnemaijer, Adriana Iglesias, Owen M. Siggs, Terri L. Young, Veronique Vitart, Alberta A. H. J. Thiadens, Juha Karjalainen, Steffen Uebe, Ronald B. Melles, K. Saidas Nair, Robert Luben, Mark Simcoe, Nishani Amersinghe, Angela J. Cree, Rene Hohn, Alicia Poplawski, Li Jia Chen, Shi-Song Rong, Tin Aung, Eranga Nishanthie Vithana, NEIGHBORHOOD consortium, ANZRAG consortium, Biobank Japan project, FinnGen study, UK Biobank Eye and Vision Consortium, GIGA study group, and Me Research Team, Gen Tamiya, Yukihiro Shiga, Masayuki Yamamoto, Toru Nakazawa, Hannah Currant, Ewan Birney, Xin Wang, Adam Auton, Michelle K. Lupton, Nicholas G. Martin, Adeyinka Ashaye, Olusola Olawoye, Susan E. Williams, Stephen Akafo, Michele Ramsay, Kazuki Hashimoto, Yoichiro Kamatani, Masato Akiyama, Yukihide Momozawa, Paul J. Foster, Peng T. Khaw, James E. Morgan, Nicholas G. Strouthidis, Peter Kraft, Jae H. Kang, Chi Pui Pang, Francesca Pasutto, Paul Mitchell, Andrew J. Lotery, Aarno Palotie, Cornelia van Duijn, Jonathan L. Haines, Chris Hammond, Louis R. Pasquale, Caroline C. W. Klaver, Michael Hauser, Chiea Chuen Khor, David A. Mackey, Michiaki Kubo, Ching-Yu Cheng, Jamie E. Craig, Stuart MacGregor, Janey L. Wiggs
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Primary open-angle glaucoma (POAG) is highly heritable, yet not well understood from a genetic perspective. Here, the authors perform a meta-analysis of genome-wide association studies in 34,179 POAG cases, identifying 44 previously unreported risk l
Externí odkaz:
https://doaj.org/article/ea46188f0f2c4f0cae58f959caf971a2
Autor:
Andrea R. Waksmunski, Michelle Grunin, Tyler G. Kinzy, Robert P. Igo, Jonathan L. Haines, Jessica N. Cooke Bailey
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-10 (2020)
Abstract Background Age-related macular degeneration (AMD) is a progressive retinal disease contributing to blindness worldwide. Multiple estimates for AMD heritability (h 2 ) exist; however, a substantial proportion of h 2 is not attributable to kno
Externí odkaz:
https://doaj.org/article/9564c35dac1847cea8b85695c2973ae7
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/9e615eb48bdf4717a539be0b41777070
Autor:
Adriana I. Iglesias, Aniket Mishra, Veronique Vitart, Yelena Bykhovskaya, René Höhn, Henriët Springelkamp, Gabriel Cuellar-Partida, Puya Gharahkhani, Jessica N. Cooke Bailey, Colin E. Willoughby, Xiaohui Li, Seyhan Yazar, Abhishek Nag, Anthony P. Khawaja, Ozren Polašek, David Siscovick, Paul Mitchell, Yih Chung Tham, Jonathan L. Haines, Lisa S. Kearns, Caroline Hayward, Yuan Shi, Elisabeth M. van Leeuwen, Kent D. Taylor, Blue Mountains Eye Study—GWAS group, Pieter Bonnemaijer, Jerome I. Rotter, Nicholas G. Martin, Tanja Zeller, Richard A. Mills, Emmanuelle Souzeau, Sandra E. Staffieri, Jost B. Jonas, Irene Schmidtmann, Thibaud Boutin, Jae H. Kang, Sionne E. M. Lucas, Tien Yin Wong, Manfred E. Beutel, James F. Wilson, NEIGHBORHOOD Consortium, Wellcome Trust Case Control Consortium 2 (WTCCC2), André G. Uitterlinden, Eranga N. Vithana, Paul J. Foster, Pirro G. Hysi, Alex W. Hewitt, Chiea Chuen Khor, Louis R. Pasquale, Grant W. Montgomery, Caroline C. W. Klaver, Tin Aung, Norbert Pfeiffer, David A. Mackey, Christopher J. Hammond, Ching-Yu Cheng, Jamie E. Craig, Yaron S. Rabinowitz, Janey L. Wiggs, Kathryn P. Burdon, Cornelia M. van Duijn, Stuart MacGregor
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Reduced central corneal thickness (CCT) is observed in common eye diseases as well as in rare Mendelian disorders. Here, in a cross-ancestry GWAS, the authors identify 19 novel genetic loci associated with CCT, a subset of which is involved in rare c
Externí odkaz:
https://doaj.org/article/f7334f0a8f8b42b18a3180c2a6650fb9
Autor:
Adriana I. Iglesias, Aniket Mishra, Veronique Vitart, Yelena Bykhovskaya, René Höhn, Henriët Springelkamp, Gabriel Cuellar-Partida, Puya Gharahkhani, Jessica N. Cooke Bailey, Colin E. Willoughby, Xiaohui Li, Seyhan Yazar, Abhishek Nag, Anthony P. Khawaja, Ozren Polašek, David Siscovick, Paul Mitchell, Yih Chung Tham, Jonathan L. Haines, Lisa S. Kearns, Caroline Hayward, Yuan Shi, Elisabeth M. van Leeuwen, Kent D. Taylor, Blue Mountains Eye Study - GWAS group, Pieter Bonnemaijer, Jerome I. Rotter, Nicholas G. Martin, Tanja Zeller, Richard A. Mills, Emmanuelle Souzeau, Sandra E. Staffieri, Jost B. Jonas, Irene Schmidtmann, Thibaud Boutin, Jae H. Kang, Sionne E. M. Lucas, Tien Yin Wong, Manfred E. Beutel, James F. Wilson, Wellcome Trust Case Control Consortium 2 (WTCCC2), NEIGHBORHOOD consortium, André G. Uitterlinden, Eranga N. Vithana, Paul J. Foster, Pirro G. Hysi, Alex W. Hewitt, Chiea Chuen Khor, Louis R. Pasquale, Grant W. Montgomery, Caroline C. W. Klaver, Tin Aung, Norbert Pfeiffer, David A. Mackey, Christopher J. Hammond, Ching-Yu Cheng, Jamie E. Craig, Yaron S. Rabinowitz, Janey L. Wiggs, Kathryn P. Burdon, Cornelia M. van Duijn, Stuart MacGregor
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-3 (2019)
Emmanuelle Souzeau, who contributed to analysis of data, was inadvertently omitted from the author list in the originally published version of this Article. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/c5c4046a0a194197ab40ff766def90b1
Autor:
Sumana R. Chintalapudi, Doaa Maria, Xiang Di Wang, Jessica N. Cooke Bailey, NEIGHBORHOOD consortium, International Glaucoma Genetics consortium, Pirro G. Hysi, Janey L. Wiggs, Robert W. Williams, Monica M. Jablonski
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Elevated intraocular pressure (IOP) is a heritable risk factor for primary open angle glaucoma. Using forward mouse genetics, cell biology, pharmacology and human genetic data, the authors identify CACNA2D1 as an IOP risk gene that can be therapeutic
Externí odkaz:
https://doaj.org/article/af4437df6004461cb8840a6beeadf9f9
Autor:
Rebecca King, Felix L Struebing, Ying Li, Jiaxing Wang, Allison Ashley Koch, Jessica N Cooke Bailey, Puya Gharahkhani, International Glaucoma Genetics Consortium, NEIGHBORHOOD Consortium, Stuart MacGregor, R Rand Allingham, Michael A Hauser, Janey L Wiggs, Eldon E Geisert
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007145 (2018)
Central corneal thickness (CCT) is one of the most heritable ocular traits and it is also a phenotypic risk factor for primary open angle glaucoma (POAG). The present study uses the BXD Recombinant Inbred (RI) strains to identify novel quantitative t
Externí odkaz:
https://doaj.org/article/52e401834a3e43f093af65653621c5f4
Autor:
Shefali Setia Verma, Jessica N Cooke Bailey, Anastasia Lucas, Yuki Bradford, James G Linneman, Michael A Hauser, Louis R Pasquale, Peggy L Peissig, Murray H Brilliant, Catherine A McCarty, Jonathan L Haines, Janey L Wiggs, Tamara R Vrabec, Gerard Tromp, Marylyn D Ritchie, eMERGE Network, NEIGHBOR Consortium
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006186 (2016)
Primary open angle glaucoma (POAG) is a complex disease and is one of the major leading causes of blindness worldwide. Genome-wide association studies have successfully identified several common variants associated with glaucoma; however, most of the
Externí odkaz:
https://doaj.org/article/f6a7103c753645719af3ca9f64a5c094