Zobrazeno 1 - 10
of 59
pro vyhledávání: '"N. Ostendorf"'
Autor:
Benjamin N. Ostendorf, Mira A. Patel, Jana Bilanovic, H.-Heinrich Hoffmann, Sebastian E. Carrasco, Charles M. Rice, Sohail F. Tavazoie
Publikováno v:
Nature. 611:346-351
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197823 (2018)
Recent reports have revealed myelodysplastic syndromes (MDS) to arise from cancer stem cells phenotypically similar to physiological hematopoietic stem cells. Myelodysplastic hematopoiesis maintains a hierarchical organization, but the proportion of
Externí odkaz:
https://doaj.org/article/1482f05217ff4f87884595b1311abb76
Publikováno v:
Biomarker Insights, Vol 2015, Iss Suppl. 3, Pp 25-28 (2015)
Externí odkaz:
https://doaj.org/article/6a04c61f05644e5ba63a7590219f31ca
The secreted lipid transporter apolipoprotein E (APOE) plays important roles in atherosclerosis and Alzheimer’s disease and has been implicated as a suppressor of melanoma progression. APOE germline genotype predicts human melanoma outcomes, as APO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::decf514209454232d16b4cc8987e91c1
https://doi.org/10.1101/2022.10.03.510632
https://doi.org/10.1101/2022.10.03.510632
Autor:
Benjamin N, Ostendorf, Mira A, Patel, Jana, Bilanovic, H-Heinrich, Hoffmann, Sebastian E, Carrasco, Charles M, Rice, Sohail F, Tavazoie
Publikováno v:
Nature. 611(7935)
Clinical outcomes of severe acute respiratory syndrome 2 (SARS-CoV-2) infection are highly heterogeneous, ranging from asymptomatic infection to lethal coronavirus disease 2019 (COVID-19). The factors underlying this heterogeneity remain insufficient
Publikováno v:
Biomarker Insights, Vol 10s3 (2015)
The management of patients with chronic myeloid leukemia (CML) in advanced phases is challenging and requires the consideration of different treatment approaches, including targeted therapy with tyrosine kinase inhibitors, cytotoxic chemotherapy, and
Externí odkaz:
https://doaj.org/article/c1ee343bd2c1493e9642025e6773c67c
Publikováno v:
Developmental Cell. 52:542-544
Cancer cells need to acquire specific molecular traits in order to spread to distant organs. In this issue of Developmental Cell, Marsh et al. show that autophagy restricts the outgrowth of breast cancer metastases in contrast to its impact on primar
Autor:
Ryan H. Moy, Alexander Nguyen, Jia Min Loo, Norihiro Yamaguchi, Christina M. Kajba, Balaji Santhanam, Benjamin N. Ostendorf, Y. Gloria Wu, Saeed Tavazoie, Sohail F. Tavazoie
Publikováno v:
Dev Cell
Developmental cell, vol 57, iss 9
Developmental cell, vol 57, iss 9
Metastatic colonization is the primary cause of death from colorectal cancer (CRC). We employed genome-scale invivo short hairpin RNA (shRNA) screening and validation to identify 26 promoters of CRC liver colonization. Among these genes, we identifie
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57078 (2013)
Mutations in the gene NPHS2 are the most common cause of hereditary steroid-resistant nephrotic syndrome. Its gene product, the stomatin family member protein podocin represents a core component of the slit diaphragm, a unique structure that bridges
Externí odkaz:
https://doaj.org/article/e18a32c59dae40cd82b70ff6da8b3328
Autor:
Alana L. Welm, Bernardo Tavora, Olav Olsen, Mahan Sadjadi, Ji-Young Kim, Kai J. Wessel, Xuhang Liu, Marc Missmahl, Sohail F. Tavazoie, Simon Ruffing, Tobias Mederer, Hani Goodarzi, Benjamin N. Ostendorf
Publikováno v:
Nature, vol 586, iss 7828
Nature
Nature
Blood vessels support tumours by providing nutrients and oxygen, while also acting as conduits for the dissemination of cancer(1). Here we use mouse models of breast and lung cancer to investigate whether endothelial cells also have active ‘instruc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85dabf1b15c20e3c62371a57549e6b11
https://escholarship.org/uc/item/2kj236dm
https://escholarship.org/uc/item/2kj236dm