Zobrazeno 1 - 10
of 48
pro vyhledávání: '"N. Obermayer"'
Autor:
Alyssa N. Obermayer, Darwin Chang, Gabrielle Nobles, Mingxiang Teng, Aik-Choon Tan, Xuefeng Wang, Y. Ann Chen, Steven Eschrich, Paulo C. Rodriguez, G. Daniel Grass, Soheil Meshinchi, Ahmad Tarhini, Dung-tsa Chen, Timothy I. Shaw
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Pathway-level survival analysis offers the opportunity to examine molecular pathways and immune signatures that influence patient outcomes. However, available survival analysis algorithms are limited in pathway-level function and lack a stre
Externí odkaz:
https://doaj.org/article/a8a184167ea846a0a4bc7b36d14d1a13
Autor:
Eric Y. Helm, Tomas Zelenka, Valeriu B. Cismasiu, Shamima Islam, Leonardo Silvane, Beatrice Zitti, Tim D. Holmes, Theodore T. Drashansky, Alexander J. Kwiatkowski, Christine Tao, Joseph Dean, Alyssa N. Obermayer, Xianghong Chen, Benjamin G. Keselowsky, Weizhou Zhang, Zhiguang Huo, Liang Zhou, Brian S. Sheridan, Jose R. Conejo-Garcia, Timothy I. Shaw, Yenan T. Bryceson, Dorina Avram
Publikováno v:
Sci Immunol
The networks of transcription factors (TFs) that control intestinal-resident memory CD8 + T (T RM ) cells, including multipotency and effector programs, are poorly understood. In this work, we investigated the role of the TF Bcl11b in T RM cells duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e2efde8429ae177eeee0aca7aa9716
https://europepmc.org/articles/PMC10231135/
https://europepmc.org/articles/PMC10231135/
Autor:
Tanja A. Gruber, Jinghui Zhang, Chunliang Li, Alberto Pappo, Joy Nakitandwe, Susana Raimondi, Teresa Santiago, Vasiliki Leventaki, Gang Wu, Yang Zhang, Jing Ma, Sarah Aldridge, Alyssa N. Obermayer, Amelia M.R. Smith, Kohei Hagiwara, Scott Newman, Alexander M. Gout, Timothy I. Shaw, Jinjun Dang, Jennifer L. Kamens
Supplementary Methods and FiguresSupplementary Figure 1. A newborn with isolated myeloid sarcoma.Supplementary Figure 2. Myeloid Sarcoma Histology.Supplementary Figure 3. Bone Marrow.Supplementary Figure 4. Genes Upregulated in CIC-NUTM2A.Supplementa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23670cd213589435a04c8fc64695de62
https://doi.org/10.1158/1541-7786.22495345.v1
https://doi.org/10.1158/1541-7786.22495345.v1
Autor:
Tanja A. Gruber, Jinghui Zhang, Chunliang Li, Alberto Pappo, Joy Nakitandwe, Susana Raimondi, Teresa Santiago, Vasiliki Leventaki, Gang Wu, Yang Zhang, Jing Ma, Sarah Aldridge, Alyssa N. Obermayer, Amelia M.R. Smith, Kohei Hagiwara, Scott Newman, Alexander M. Gout, Timothy I. Shaw, Jinjun Dang, Jennifer L. Kamens
Myeloid sarcoma is a rare condition consisting of extramedullary myeloid blasts found in association with acute myeloid leukemia or, in the absence of bone marrow involvement. We identified an infant with isolated myeloid sarcoma whose bone marrow wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc64f8f2492e4398d6986bb804922672
https://doi.org/10.1158/1541-7786.c.6534832.v1
https://doi.org/10.1158/1541-7786.c.6534832.v1
Autor:
Tanja A. Gruber, Jinghui Zhang, Chunliang Li, Alberto Pappo, Joy Nakitandwe, Susana Raimondi, Teresa Santiago, Vasiliki Leventaki, Gang Wu, Yang Zhang, Jing Ma, Sarah Aldridge, Alyssa N. Obermayer, Amelia M.R. Smith, Kohei Hagiwara, Scott Newman, Alexander M. Gout, Timothy I. Shaw, Jinjun Dang, Jennifer L. Kamens
Supplementary Table 1. Validated Tier 1-3 Mutation CallsSupplementary Table 2. Genes Upregulated in CIC-NUTM2ASupplementary Table 3. CIC-NUTM2A Gene Set Enrichment Analysis in Pediatric Hematologic MalignanciesSupplementary Table 4. ssGSEA for Top Sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f132a3df9d78380038efd4c3b320cb
https://doi.org/10.1158/1541-7786.22495342
https://doi.org/10.1158/1541-7786.22495342
Autor:
Jessica K. Mandula, Shiun Chang, Eslam Mohamed, Rachel Jimenez, Rosa A. Sierra-Mondragon, Darwin C. Chang, Alyssa N. Obermayer, Carlos M. Moran-Segura, Satyajit Das, Julio A. Vazquez-Martinez, Karol Prieto, Ann Chen, Keiran S.M. Smalley, Brian Czerniecki, Peter Forsyth, Richard C. Koya, Brian Ruffell, Juan R. Cubillos-Ruiz, David H. Munn, Timothy I. Shaw, Jose R. Conejo-Garcia, Paulo C. Rodriguez
Publikováno v:
Cancer cell. 40(10)
Activation of unfolded protein responses (UPRs) in cancer cells undergoing endoplasmic reticulum (ER) stress promotes survival. However, how UPR in tumor cells impacts anti-tumor immune responses remains poorly described. Here, we investigate the rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af984ec1f98ddfd3c289264834a756c
https://pubmed.ncbi.nlm.nih.gov/36150390
https://pubmed.ncbi.nlm.nih.gov/36150390
Autor:
Alyssa N. Obermayer, Timothy I. Shaw, Sandra J. Lee, F. Stephen Hodi, William A. LaFramboise, Walter Storkus, Arivarasan D. Karunamurthy, Patrick Hwu, Howard Streicher, Dung-Tsa Chen, John M. Kirkwood, Ahmad A. Tarhini
Publikováno v:
Cancer Research. 83:5704-5704
Introduction CTLA4 blockade with ipilimumab was more favorable than interferon-α2b (IFN) in high-risk melanoma in phase adjuvant III trial E1609. Characterization of the pretreatment tumor immune biomarkers and clinical covariates may inform the lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b390e35eb9ddf29200ab0c57b2d7baaa
https://doi.org/10.1158/1538-7445.am2023-5704
https://doi.org/10.1158/1538-7445.am2023-5704
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