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pro vyhledávání: '"N. Nagasundaram"'
Autor:
Nguyen Quoc Khanh Le, Edward Kien Yee Yapp, N. Nagasundaram, Matthew Chin Heng Chua, Hui-Yuan Yeh
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 1245-1254 (2019)
Protein function prediction is one of the most well-studied topics, attracting attention from countless researchers in the field of computational biology. Implementing deep neural networks that help improve the prediction of protein function, however
Externí odkaz:
https://doaj.org/article/9646c28df7d84d548ffd12b2bf8a33d0
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
A promoter is a short region of DNA (100–1,000 bp) where transcription of a gene by RNA polymerase begins. It is typically located directly upstream or at the 5′ end of the transcription initiation site. DNA promoter has been proven to be the pri
Externí odkaz:
https://doaj.org/article/56a25f8e086c440d8c55f5ce11689bdb
Publikováno v:
Materials Today: Proceedings. 27:565-570
However, over the past fifty years the rapid growth in the development of harder, tougher and stronger work piece materials. The 4340 steel is a medium carbon, low alloy steel (Heat-treatable). It has excellent toughness, superior strength in the hea
Publikováno v:
Materials Today: Proceedings. 45:2286-2288
In recent days, moulding of thermoplastic is difficult process. Injection moulding is one of the most imperative plastic processing technologies. The melted plastics were passed to the closed die unit through thrust of the screw or plunger. In this e
Autor:
Chandrasekhar Gopalakrishnan, N. Nagasundaram, Abeer M. Al-Subaie, Balu Kamaraj, Hui-Yuan Yeh, Iftikhar Alam Tayubi
Publikováno v:
Journal of Cellular Biochemistry. 120:18496-18508
Lysinuric protein intolerance (LPI) is a rare, yet inimical, genetic disorder characterized by the paucity of essential dibasic amino acids in the cells. Amino acid transporter y+LAT-1 interacts with 4F2 cell-surface antigen heavy chain to transport
Autor:
Nguyen Quoc Khanh Le, Yu-Yen Ou, Quang-Thai Ho, N. Nagasundaram, Edward Kien Yee Yapp, Hui-Yuan Yeh
Publikováno v:
Analytical Biochemistry. 571:53-61
An enhancer is a short (50–1500bp) region of DNA that plays an important role in gene expression and the production of RNA and proteins. Genetic variation in enhancers has been linked to many human diseases, such as cancer, disorder or inflammatory
Autor:
Ramamoorthy Siva, Iftikhar Aslam Tayubi, N. Nagasundaram, Aisha Saleem, Karthick Vasudevan, D. Thirumal Kumar, S. Udhaya Kumar, Hatem Zayed, C. George Priya Doss
Publikováno v:
Current opinion in pharmacology. 61
The World Health Organization declared Ebola virus disease (EVD) as the major outbreak in the 20th century. EVD was first identified in 1976 in South Sudan and the Democratic Republic of the Congo. EVD was transmitted from infected fruit bats to huma
Autor:
C George Priya Doss, N Nagasundaram
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31677 (2012)
BackgroundElucidating the molecular dynamic behavior of Protein-DNA complex upon mutation is crucial in current genomics. Molecular dynamics approach reveals the changes on incorporation of variants that dictate the structure and function of Protein-
Externí odkaz:
https://doaj.org/article/c7d0743bc3d840ad9340024731ceb224
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Autor:
N. Nagasundaram, Rajesh Kannan Rajaretinam, Carlton Ranjith Wilson Alphonse, Prakash Vincent Samuel Gnana
Publikováno v:
Journal of Cellular Biochemistry. 118:3462-3471
Anaplastic lymphoma kinase (ALK) positive non-small cell lung cancer (NSCLC) patients are mostly treated with ALK tyrosine kinase inhibitors (TKIs). Crizotinib is the first generation ALK inhibitor practiced as a primary chemo to combat cancer cells