Zobrazeno 1 - 10
of 46
pro vyhledávání: '"N. N. Nikolsky"'
Autor:
L. L. Alekseenko, M. A. Shilina, O. G. Lyublinskaya, J. S. Kornienko, O. V. Anatskaya, A. E. Vinogradov, T. M. Grinchuk, I. I. Fridlyanskaya, N. N. Nikolsky
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Quiescence is the prevailing state of many cell types under homeostatic conditions. Yet, surprisingly, little is known about how quiescent cells respond to environmental challenges. The aim of the present study is to compare stress responses of cycli
Externí odkaz:
https://doaj.org/article/9dcbfdd48290421c9ea4a41bfc1279c3
Autor:
A. E. Vinogradov, M. A. Shilina, O. V. Anatskaya, L. L. Alekseenko, I. I. Fridlyanskaya, A. Krasnenko, A. Kim, D. Korostin, V. Ilynsky, A. Elmuratov, O. Tsyganov, T. M. Grinchuk, N. N. Nikolsky
Publikováno v:
Stem Cells International, Vol 2017 (2017)
High temperature is a critical environmental and personal factor. Although heat shock is a well-studied biological phenomenon, hyperthermia response of stem cells is poorly understood. Previously, we demonstrated that sublethal heat shock induced pre
Externí odkaz:
https://doaj.org/article/728a02e5621f424d9b5862bcf1c5c3f8
Autor:
K. V. Gorunov, I. V. Kozhukharova, Olga G. Lyublinskaya, Yu. S. Ivanova, N. A. Pugovkina, Tatyana M. Grinchuk, M. A. Shilina, N. N. Nikolsky, D. N. Silachev
Publikováno v:
Cell and Tissue Biology. 14:196-201
Chorion is the outer fetal membrane around embryo that develops from the trophoblast and the underlying mesenchyme. The objective of this work was to characterize cell lines obtained from chorion of different donors. The expression profile of surface
Autor:
I. I. Marakhova, A. P. Domnina, V. I. Zemelko, N. A. Pugovkina, Alla N. Shatrova, N. N. Nikolsky, T. A. Vinogradova
Publikováno v:
Cell and Tissue Biology. 13:170-175
Ionic homeostasis of human mesenchymal stem cells (MSCs) during their long-term cultivation was studied. It was found that, at early passages (second to fourth), the intracellular K+ content calculated for total cellular protein was almost 40% higher
Autor:
N. A. Pugovkina, N. N. Nikolsky, Alla N. Shatrova, T. A. Vinogradova, I. I. Marakhova, A. P. Domnina, V. I. Zemelko
Publikováno v:
Cell and Tissue Biology. 13:93-99
In this study, we reported proliferation-related changes in cell K+ and Na+ content and K+ influxes in cultivated human mesenchymal stem cells (MSCs). The intracellular K+ content calculated per cell protein amount was found to decrease in the growin
Publikováno v:
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 12:223-233
“Our oldness is a disease that has to be treated like any other one,”—this statement formulated about a hundred years ago seems to be of current interest in the context of modern investigations. Recently, it has been established that accumulati
Autor:
V. I. Chubinskiy-Nadezhdin, Valeria Y. Vasileva, Olga G. Lyublinskaya, Anastasia V. Sudarikova, N. N. Nikolsky, M. A. Shilina, Yuri A. Negulyaev, Tatiana Grinchuk
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
The study of ion channels in stem cells provides important information about their role in stem cell fate. Previously we have identified the activity of calcium-activated potassium channels of big conductance (BK channels) in human endometrium-derive
Autor:
Olga G. Lyublinskaya, N. A. Pugovkina, Tatyana M. Grinchuk, Ju. S. Kornienko, N. N. Nikolsky, N. D. Aksenov, M. A. Shilina, Alla N. Shatrova, V. V. Zenin, Irina Smirnova, Ju. S. Ivanova
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Stress-induced premature senescence program is known to be activated in cells by various genotoxic stressors, and oxidative stress is considered to be the main of those. To this end, many studies discover antioxidants as protective anti-aging agents.
Publikováno v:
Cell and Tissue Biology. 10:365-371
Our recent findings demonstrate that human endometrium-derived mesenchymal stem cells (hMESCs) respond to sublethal oxidative stress by stress-induced premature senescence via the АТМ/Chk2/p53/p21/Rb pathway. Application of SB203580 (SB) inhibitor
Autor:
A. P. Domnina, Polina V. Novikova, I. I. Fridlyanskaya, M. A. Shilina, N. N. Nikolsky, V. V. Zenin
Publikováno v:
Cell and Tissue Biology. 10:95-99
In this study, we compared the ability of human mesenchymal stem cells derived from menstrual blood (eMSCs) and mesenchymal stem cells (MSCs) from other tissues to differentiate into decidual cells in vitro. It was demonstrated that during differenti