Zobrazeno 1 - 4
of 4
pro vyhledávání: '"N. M. de Wit"'
Autor:
D. Vacondio, H. Nogueira Pinto, L. Coenen, I. A. Mulder, R. Fontijn, B. van het Hof, W. K. Fung, A. Jongejan, G. Kooij, N. Zelcer, A. J. Rozemuller, H. E. de Vries, N. M. de Wit
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-14 (2023)
Abstract In Alzheimer’s disease (AD) more than 50% of the patients are affected by capillary cerebral amyloid-angiopathy (capCAA), which is characterized by localized hypoxia, neuro-inflammation and loss of blood-brain barrier (BBB) function. Moreo
Externí odkaz:
https://doaj.org/article/32d8b02e24794774aae5c3921f638265
Autor:
L, van Olst, L, Coenen, J M, Nieuwland, C, Rodriguez-Mogeda, N M, de Wit, A, Kamermans, J, Middeldorp, H E, de Vries
Publikováno v:
van Olst, L, Coenen, L, Nieuwland, J M, Rodriguez-Mogeda, C, de Wit, N M, Kamermans, A, Middeldorp, J & de Vries, H E 2022, ' Crossing borders in Alzheimer's disease : A T cell's perspective ', Advanced Drug Delivery Reviews, vol. 188, 114398, pp. 114398 . https://doi.org/10.1016/j.addr.2022.114398
Alzheimer's disease (AD) is the most common form of dementia affecting millions of people worldwide. While different immunotherapies are imminent, currently only disease-modifying medications are available and a cure is lacking. Over the past decade,
Publikováno v:
Chakraborty, A, de Wit, N M, van der Flier, W M & de Vries, E 2017, ' The blood brain barrier in Alzheimer's disease ', Vascular Pharmacology, vol. 89, pp. 12-18 . https://doi.org/10.1016/j.vph.2016.11.008
Alzheimer's disease (AD) is the most common form of dementia, affecting millions of people worldwide. One of the prominent causative factors of AD pathogenesis is cerebral vascular dysfunction, which results in diminished cerebral perfusion. Moreover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1acca20c53e9ff7694829c86c2f0c49a
https://research.vumc.nl/en/publications/8df45d6b-646b-46f3-b2d6-6584b43cab27
https://research.vumc.nl/en/publications/8df45d6b-646b-46f3-b2d6-6584b43cab27
Publikováno v:
de Wit, N M, Vanmol, J, Kamermans, A, Hendriks, J J A & de Vries, H E 2017, ' Inflammation at the blood-brain barrier : The role of liver X receptors ', Neurobiology of Disease, vol. 107, pp. 57-65 . https://doi.org/10.1016/j.nbd.2016.09.015
Neurobiology of Disease, Vol 107, Iss, Pp 57-65 (2017)
Neurobiology of Disease, Vol 107, Iss, Pp 57-65 (2017)
The blood-brain barrier (BBB) is indispensable for the maintenance of brain homeostasis and proper neuronal functioning. Dysfunction of the BBB significantly contributes to the pathogenesis of neuroinflammatory and neurodegenerative diseases like str